Abstract: An exhaust heat exchanger with catalyst to be used in an exhaust system of an internal combustion engine is provided. A catalyst chamber is disposed within a water chamber which a cooling water flows through. An exhaust gas having passed through the catalyst chamber in contact with a catalyst makes an indirect heat exchange with the cooling water before it is discharged outside. The water chamber is formed surrounded by an inner trunk and an outer trunk, and the catalyst chamber is formed by a cylindrical body disposed coaxially with the inner and outer trunks and housing the catalyst. A spiral passage for the exhaust gas is formed between the inner trunk and the cylindrical body. A plurality of heat transmitting pipes are arranged within the water chamber surrounding the inner trunk circumferentially at regular intervals. The exhaust gas having passed through the catalyst flows within the spiral passage and the heat transmitting pipes in turn to make a heat exchange with the cooling water.

Abstract: An anti-amnestic agent which comprises as an active ingredient thereof at least one prolinal derivative of the general formula: ##STR1## wherein A is a protective groups for amino group in the field of amino acid chemistry and X is a residue of an amino acid, in a pharmacologically active amount together with an exipient. This agent is less toxic and can be safely administered to patients orally or intravenously for the remedy of memory disorder.

Abstract: New camptothecin derivatives possessing either or both of high anti-tumor activity and slight toxicity, represented by the general formula: ##STR1## wherein X is H, CH.sub.2 OH, COOH, an alkyl group, an aralkyl group or the grouping CH.sub.2 OR.sup.1 or COOR.sup.2 wherein R.sup.1 is an alkyl group or an acyl group and R.sup.2 is a lower alkyl group, Y is H, OH or the grouping OR.sup.3 wherein R.sup.3 is a lower alkyl group or an acyl group, and Z is H or an acyl group, with the proviso that when X is CH.sub.2 OH, an alkyl group or an aralkyl group, both Y and Z are H, that when X is the grouping CH.sub.2 OR.sup.1 or COOR.sup.2, Y is H, that when Y is OH, both X and Z are H, and that when Y is the grouping OR.sup.3, X is H, and water-soluble alkali metal salts thereof.

Abstract: New camptothecin derivatives possessing either or both of high anti-tumor activity and slight toxicity, represented by the general formula: ##STR1## wherein X is H, CH.sub.2 OH, COOH, an alkyl group, an aralkyl group or the grouping CH.sub.2 OR.sup.1 or COOR.sup.2 wherein R.sup.1 is an alkyl group or an acyl group and R.sup.2 is a lower alkyl group, Y is H, OH or the grouping OR.sup.3 wherein R.sup.3 is a lower alkyl group or an acyl group, and Z is H or an acyl group, with the proviso that when X is CH.sub.2 OH, an alkyl group or an aralkyl group, both Y and Z are H, that when X is the grouping CH.sub.2 OR.sup.1 or COOR.sup.2, Y is H, that when Y is OH, both X and Z are H, .[.and.]. that when Y is the grouping OR.sup.3, X is H, .Iadd.and that X, Y and Z are not each simultaneously hydrogen, .Iaddend.and water-soluble alkali metal salts thereof.