Abstract: By using a medium containing an ingredient for activating brewer's yeast, a brewer's yeast cell body is immersed in the medium in the presence of an added inorganic salt; and the immersion is stirred at a predetermined temperature to concurrently carry out an aerobic activation treatment, resulting in the formation of a brewer's yeast cell body containing a high ribonucleic acid content comprising 10% by weight or more of ribonucleic acid based on the weight of the cell body.

Abstract: By using a medium containing an ingredient for activating brewer's yeast, a brewer's yeast cell body is immersed in the medium in the presence of an added inorganic salt; and the immersion is stirred at a predetermined temperature to concurrently carry out an aerobic activation treatment, resulting in the formation of a brewer's yeast cell body containing a high ribonucleic acid content comprising 10% by weight or more of ribonucleic acid based on the weight of the cell body.

Abstract: A method for producing a nucleic acid-rich yeast extract from a yeast cell suspension by an enzyme addition method, wherein the pH of the yeast cell suspension is first adjusted to neutral or alkaline (6.5-11.0), and the suspension is heated to a prescribed temperature (70-95° C.) to produce a nucleic acid-rich yeast extract.

Abstract: By using a medium containing an ingredient for activating brewer's yeast, a brewer's yeast cell body is immersed in the medium in the presence of an added inorganic salt; and the immersion is stirred at a predetermined temperature to concurrently carry out an aerobic activation treatment, resulting in the formation of a brewer's yeast cell body containing a high ribonucleic acid content comprising 10% by weight or more of ribonucleic acid based on the weight of the cell body.

Abstract: A method for preparing a solid fermentation-promoting substance, the method including the steps of: subjecting a residue obtainable from the process of production of a fermented liquor to acid treatment and separating supernatant from the acid treatment to obtain a liquid fermentation-promoting substance; and subjecting the resulting liquid fermentation-promoting substance to neutralization treatment to obtain the solid fermentation-promoting substance.

Abstract: The present invention has for its object to provide a method for obtaining a barley malt oil abundantly containing ceramide derivatives of plant origin which is highly safe and gives a good image as a material in an efficient, simple and easy manner as well as to provide a barley malt oil which is obtained by such method above and is enriched in highly safe ceramide derivatives. The present invention provides a method for producing barley malt oil containing ceramide derivatives, comprising the steps of: dipping spent grains obtained in a process of beer production in a polar organic solvent as a dipping solution, separating an extract liquid from the dipping solution, and concentrating the extract liquid and also provides a barley malt oil containing ceramide derivatives obtainable by dipping spent grains obtained in a process of beer production in a polar organic solvent, separating an extract liquid from the resulting solution, and concentrating the extract liquid.

Abstract: In accordance with the present invention, it is provided a method for producing a yeast extract with the improvement in the color and odor characteristic to yeast extract and with no modification of the useful substances such as amino acid, etc. compared with conventional yeast extract.By a simple method in accordance with the present invention, color and characteristic odor can be removed, with almost no loss of the contents of useful substances such as amino acid, etc. from the yeast extract solution produced in a conventional manner. Because the resulting yeast extract can be mixed with other materials for use, the yeast extract is applicable to various fields, for example for cosmetic products and healthy foods other than seasonings, which expectantly enlarges the applicable range of the yeast extract.

Abstract: A polysaccharide RON substance which has antitumor activity can be produced by fermenting sucrose with a synthetase. The synthetase can be isolated from Leuconostoc strains. Preferred strains of the microorganism are Leuconostoc mesenteroides FERM BP-2242, 2711, 2712, 2713, 2714, and 2670. The substance exhibits antitumor activity against syngenic tumor Meth A, a transplantable tumor in mice.

Abstract: A method is provided for preparing an antitumor dextran by contacting a culture broth containing sucrose with an antitumor dextran obtained from Lactobacillus confusus and collecting the antitumor dextran from the culture broth. The enzyme can be used as a crude enzyme solution or may be further purified by conventional means. The Lactobacillus confusus is preferably one of the following: 40-1 strain (FERM BP-2865) , 40-3 strain (FERM BP-2866) , 77-1 strain (FERM BP-2867), 78-1 strain (FERM BP-2868) or 80-1 strain (FERM BP-2869).

Abstract: Lactobacillus confusus strains capable of producing a dextran which has biological activities such as an excellent antitumor activity, etc. are disclosed. Also disclosed is a method for producing said dextran using said microorganism or dextran synthetase prepared by said microorganism.

Abstract: A biologically active polysaccharide RON substance which is excellent in such biological activities as antitumor activities, is produced by using a microorganism belonging to the genus Leuconostoc, which has an activity of producing the RON substance.

Abstract: A polysaccharide RDP substance having the ultraviolet absorption spectrum depicted in FIG. 1, the infrared absorption spectrum depicted in FIG. 2 and the .sup.13 C-NMR spectrum depicted in FIG. 3 is obtained from rice bran by extraction.

Abstract: A polysaccharide RON substance having the ultraviolet absorption spectrum depicted in FIG. 1, the infrared absorption spectrum depicted in FIG. 2 and the .sup.13 C-NMR spectrum depicted in FIG. 3 is obtained from rice bran by extraction and purification; and pharmacological composition containing said RON substance.