Abstract: An arousal state estimation apparatus includes: a feature value acquisition unit acquiring a plurality of types of feature values regarding an arousal state of a human body from physiological data obtained by measuring the human body; and an estimation unit estimating the arousal state of the human body by using a principal feature value that is some type among the plurality of types of feature values. In a case where the principal feature value is unacquirable due to a defect of the physiological data, the estimation unit estimates the arousal state of the human body by using a different type of feature value than the principal feature value among the plurality of types of feature values acquired by the feature value acquisition unit instead of the unacquirable principal feature value.

Abstract: [Problem] The present invention pertains to a safer and more effective respiratory infection treating agent. [Solution] A respiratory infection treating agent containing, as an active ingredient, 7-[(3S,4S)-3-{(cyclopropylamino)methyl}-4-fluoropyrrolidine-1-yl]-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquin oline-3-carboxylic acid or a pharmaceutically acceptable salt thereof.

Abstract: [Problem] The present invention pertains to a safer and more effective respiratory infection treating agent. [Solution] A respiratory infection treating agent containing, as an active ingredient, 7-[(3S,4S)-3-{(cyclopropylamino)methyl}-4-fluoropyrrolidine-1-yl]-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof.

Abstract: An arousal state estimation apparatus includes: a feature value acquisition unit acquiring a plurality of types of feature values regarding an arousal state of a human body from physiological data obtained by measuring the human body; and an estimation unit estimating the arousal state of the human body by using a principal feature value that is some type among the plurality of types of feature values. In a case where the principal feature value is unacquirable due to a defect of the physiological data, the estimation unit estimates the arousal state of the human body by using a different type of feature value than the principal feature value among the plurality of types of feature values acquired by the feature value acquisition unit instead of the unacquirable principal feature value.

Abstract: [Problem] The present invention pertains to a safer and more effective respiratory infection treating agent. [Solution] A respiratory infection treating agent containing, as an active ingredient, 7-[(3S,4S)-3-{(cyclopropylamino)methyl}-4-fluoropyrrolidine-1-yl]-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof.

Abstract: [Problem] The present invention pertains to a safer and more effective respiratory infection treating agent. [Solution] A respiratory infection treating agent containing, as an active ingredient, 7-[(3S,4S)-3-{(cyclopropylamino)methyl}-4-fluoropyrrolidine-1-yl]-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof.

Abstract: An integrated circuit device includes a barrier layer as an underlying layer for a wiring conductor layer. The barrier layer is formed of titanium oxide-titanium nitride or titanium nitride or composite layers of titanium, 2-titanium nitride and titanium nitride. The barrier layer may contain oxygen or carbon. A method of manufacturing an integrated circuit device includes steps of introducing a gas to the vicinity of a substrate disposed within a vacuum chamber, and forming a titanium oxide-titanium nitride thin film or titanium nitride film or the composite film by depositing titanium in vapor phase by using a cluster-type ion source while irradiating the substrate with nitrogen ions. A thin film forming apparatus comprises a cluster type ion source and a gas ion source.