Patents by Inventor Hisashi Hagiwara
Hisashi Hagiwara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170106369Abstract: A microchip comprises a plurality of laminated elastic sheets, wherein the elastic sheets are partially inadhesive each other so that at least 3 middle layers are formed; as a first middle layer, first flow path and second flow path through which liquid flows are formed; as a second middle layer, a first flow path opening/closing section for opening and closing the first flow path is formed; and as a third middle layer, a second flow path opening/closing section for opening and closing the second flow path is formed.Type: ApplicationFiled: March 19, 2015Publication date: April 20, 2017Applicant: NEC CorporationInventors: Minoru ASOGAWA, Yoshinori MISHINA, Hisashi HAGIWARA, Yasuo IIMURA
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Publication number: 20170106370Abstract: An amplification apparatus comprises an amplification unit, monitoring unit and control unit. The amplification unit is a means for amplifying desired nucleic acid sequence by heating and cooling sample solution. The monitoring unit is a means for monitoring amount of amplicon as nucleic acid sequence amplified by the amplification unit. The control unit is a means for terminating amplification process by the amplification unit based on the amount of amplicon monitored by the monitoring unit.Type: ApplicationFiled: March 31, 2014Publication date: April 20, 2017Applicant: NEC CorporationInventors: Minoru ASOGAWA, Yoshinori MISHINA, Yasuo IIMURA, Hisashi HAGIWARA, Ryou YAMAZAKI
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Patent number: 9586205Abstract: An analysis chip device according to an exemplary embodiment of the present invention includes a placing board (17) on which a microchip (14) is placed, and a coupling (20) attached to a cover (11) of the microchip (14). The coupling (20) includes a linear electrode (25), a sleeve (22) including an attach part (28) that is attached to the cover (11) and an air core part (23) in which the electrode (25) is provided, the sleeve (22) having a side surface in which an inlet port (26) is provided, the inlet port (26) communicating with the air core part (23); and a holder (21) including a pipe connection part (27) to which a pipe (32) is connected, the pipe (32) supplying gas to the inlet port (26), the holder (21) holding the sleeve (22) so as to surround the inlet port (26).Type: GrantFiled: July 8, 2013Date of Patent: March 7, 2017Assignee: NEC CORPORATIONInventors: Minoru Asogawa, Yoshinori Mishina, Yasuo Iimura, Hisashi Hagiwara
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Publication number: 20170022539Abstract: The present invention provides a chip for analysis of a target substance that is compact and allows analysis of a target substance with less time and effort. The chip for analysis of a target substance includes a first flexible substrate 1, a second flexible substrate 2, and a third substrate 3. A flow channel-forming non-bonded area 11 is formed on a bonding surface of the first flexible substrate 1 and the second flexible substrate 2 in a band-like manner and an extraction chamber-forming non-bonded area 5 having a wider band width than the flow channel-forming non-bonded area 11 is formed at a part of the flow channel-forming non-bonded area 11.Type: ApplicationFiled: April 15, 2016Publication date: January 26, 2017Inventors: Minoru ASOGAWA, Hisashi HAGIWARA, Yoshinori MISHINA, Yasuo IIMURA
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Publication number: 20160288119Abstract: A microchip comprises a PCR section, a denaturing section, and an electrophoresis section. In the PCR section, a desired region in DNA is amplified. In the denaturing section, PCR amplicon of double-strand DNA is denatured into single-strand DNA. In the electrophoresis section, the PCR amplicon is separated based on the length of sequence.Type: ApplicationFiled: March 6, 2014Publication date: October 6, 2016Inventors: Minoru ASOGAWA, Hisashi HAGIWARA, Yoshinori MISHINA, Yasuo IIMURA
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Publication number: 20160290962Abstract: An electrophoresis apparatus includes a membrane heater and controller. The membrane heater is supplied with power from a power supply and has a self-temperature control function. At the time of electrophoresis using a capillary extending inside of a microchip in a first direction, the controller controls supply of power from the power supply to the membrane heater arranged so as to supply heat to a capillary to keep the capillary at an even temperature.Type: ApplicationFiled: February 20, 2014Publication date: October 6, 2016Inventors: Minoru ASOGAWA, Hisashi HAGIWARA, Yoshinori MISHINA, Yasuo IIMURA
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Patent number: 9380994Abstract: An ultrasonic diagnostic apparatus according to the present invention includes: a transmitting section, which drives a probe that transmits an ultrasonic wave toward a subject; a receiving section, which receives an ultrasonic echo, produced by getting the ultrasonic wave reflected by the subject, through the probe, thereby generating a received signal; a property value calculating section for calculating property values of the subject based on the received signal over a period of time; a stability estimating section for sequentially estimating the degrees of stability of the property values that have been calculated over the period of time; and a presenting section for presenting the degrees of stability thereon.Type: GrantFiled: December 19, 2005Date of Patent: July 5, 2016Assignee: KONICA MINOLTA, INC.Inventors: Takao Seki, Takao Suzuki, Hisashi Hagiwara, Yoshinao Tannaka, Yoshinobu Watanabe, Makoto Kato
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Publication number: 20160158747Abstract: A sample processing device for a microchip, including: a sample vessel for packing a sample therein; and a reaction vessel which is continuous with the sample vessel through a channel, and to which the sample is sequentially delivered to be packed and mixed therein, in which the sample is repeatedly delivered between the sample vessel and the reaction vessel through the channel so that the sample is stirred and mixed.Type: ApplicationFiled: February 17, 2016Publication date: June 9, 2016Inventors: Minoru ASOGAWA, Hisashi HAGIWARA, Tohru HIRAMATSU
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Publication number: 20150298127Abstract: Disclosed is a fluidic chip or the like comprising a structure that does not leak a fluid to the exterior. This fluidic chip has at least two elastic members layered in an intermediate layer provided between a top substrate and a bottom substrate. An attached region, in which the elastic members are mutually attached, and a first non-attached region, in which the elastic members are not attached, are provided between the elastic member layers, and a recess in which a fluid can be stored is formed in the top substrate. In addition, the fluidic chip is provided with a through-hole that communicates between the bottom of the recess and one elastic member, of the at least two elastic members, that is attached to the top substrate side. A channel for the fluid is formed by mutual separation of the layers that form the first non-attached region in accordance with the pressurization by the fluid. The fluid that passes through the region is stored in the recess via the through-hole.Type: ApplicationFiled: November 19, 2013Publication date: October 22, 2015Inventors: Minoru Asogawa, Yoshinori Mishina, Yasuo Iimura, Hisashi Hagiwara
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Publication number: 20150251180Abstract: An analysis chip device according to an exemplary embodiment of the present invention includes a placing board (17) on which a microchip (14) is placed, and a coupling (20) attached to a cover (11) of the microchip (14). The coupling (20) includes a linear electrode (25), a sleeve (22) including an attach part (28) that is attached to the cover (11) and an air core part (23) in which the electrode (25) is provided, the sleeve (22) having a side surface in which an inlet port (26) is provided, the inlet port (26) communicating with the air core part (23); and a holder (21) including a pipe connection part (27) to which a pipe (32) is connected, the pipe (32) supplying gas to the inlet port (26), the holder (21) holding the sleeve (22) so as to surround the inlet port (26).Type: ApplicationFiled: July 8, 2013Publication date: September 10, 2015Applicant: NEC Corporation,Inventors: Minoru Asogawa, Yoshinori Mishina, Yasuo Iimura, Hisashi Hagiwara
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Patent number: 9126552Abstract: A passenger protection system includes: first and second sensors that detect an impact applied to a vehicle in a width direction; a determination device that determines a collision by comparing a first detection signal from the first sensor with a first determination condition, and by comparing a second detection signal from the second sensor with a second determination condition; and a boarding position detector that detects a boarding position of a passenger. The determination device sets the first determination condition and the second determination condition according to the boarding position in such a manner that the first determination condition is different from the second determination condition.Type: GrantFiled: May 28, 2014Date of Patent: September 8, 2015Assignees: DENSO CORPORATION, Toyota Jidosha Kabushiki KaishaInventors: Yuu Nakazawa, Yasuo Imamura, Yusuke Mase, Hisashi Hagiwara
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Publication number: 20150225771Abstract: An analysis chip capable of introducing a sample into a capillary without failure and an analysis device using the analysis chip are provided. An analysis chip (10) includes a first channel (64) through which a liquid sample flows together with gas; a second channel into which the sample from the first channel (64) is introduced; and a phoresis tank (69) that stores the sample between the first channel (64) and the second channel, at least a bottom surface of the phoresis tank (69) on a side of the second channel being subjected to a treatment to increase a wettability with respect to the liquid.Type: ApplicationFiled: April 5, 2013Publication date: August 13, 2015Inventors: Minoru Asogawa, Yoshinori Mishina, Yasuo IImura, Hisashi Hagiwara
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Publication number: 20150050721Abstract: The present invention provides a chip for analysis of a target substance that is compact and allows analysis of a target substance with less time and effort. The chip for analysis of a target substance includes a first flexible substrate 1, a second flexible substrate 2, and a third substrate 3. A flow channel-forming non-bonded area 11 is formed on a bonding surface of the first flexible substrate 1 and the second flexible substrate 2 in a band-like manner and an extraction chamber-forming non-bonded area 5 having a wider band width than the flow channel-forming non-bonded area 11 is formed at a part of the flow channel-forming non-bonded area 11.Type: ApplicationFiled: January 23, 2013Publication date: February 19, 2015Inventors: Minoru Asogawa, Hisashi Hagiwara, Yoshinori Mishina, Yasuo Iimura
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Publication number: 20140358379Abstract: A passenger protection system includes: first and second sensors that detect an impact applied to a vehicle in a width direction; a determination device that determines a collision by comparing a first detection signal from the first sensor with a first determination condition, and by comparing a second detection signal from the second sensor with a second determination condition; and a boarding position detector that detects a boarding position of a passenger. The determination device sets the first determination condition and the second determination condition according to the boarding position in such a manner that the first determination condition is different from the second determination condition.Type: ApplicationFiled: May 28, 2014Publication date: December 4, 2014Applicants: DENSO CORPORATION, Toyota Jidosha Kabushiki KaishaInventors: Yuu Nakazawa, Yasuo Imamura, Yusuke Mase, Hisashi Hagiwara
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Patent number: 8845980Abstract: Provided is a sample packing device for packing a sample with respect to a microchip for performing reaction of a micro component contained in the sample, the microchip at least including: a sample reservoir; a reaction reservoir; and a channel connected between the sample reservoir and the reaction reservoir, in which a package including a sample chamber packed in advance with the sample is mounted on the microchip so as to pack the sample in the sample chamber into the sample reservoir.Type: GrantFiled: May 21, 2013Date of Patent: September 30, 2014Assignee: NEC CorporationInventors: Minoru Asogawa, Hisashi Hagiwara, Tohru Hiramatsu
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Patent number: 8741231Abstract: A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.Type: GrantFiled: November 18, 2013Date of Patent: June 3, 2014Assignee: NEC CorporationInventors: Minoru Asogawa, Hisashi Hagiwara, Tohru Hiramatsu
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Publication number: 20140079605Abstract: A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.Type: ApplicationFiled: November 18, 2013Publication date: March 20, 2014Applicant: NEC CORPORATIONInventors: Minoru ASOGAWA, Hisashi HAGIWARA, Tohru HIRAMATSU
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Patent number: 8623294Abstract: A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.Type: GrantFiled: March 18, 2009Date of Patent: January 7, 2014Assignee: NEC CorporationInventors: Minoru Asogawa, Hisashi Hagiwara, Tohru Hiramatsu
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Patent number: 8591417Abstract: There are provided a transmission unit (102) and a reception unit (103) for transmitting and receiving an ultrasonic wave with respect to a subject, a tissue tracing unit (115) for analyzing a received signal to trace the movement of a tissue of the subject, and a property detection unit (120) for detecting a property concerning the movement of the tissue of the subject. The property detection unit (120) subjects either one of the received signal, a Doppler shift, and the movement of the tissue of the subject to signal processing, detects a property concerning the movement of the tissue of the subject that is in synchronization with a heartbeat, and generates an initializing pulse based on the detected property. The tissue tracing unit (115) is initialized by the initializing pulse.Type: GrantFiled: May 19, 2004Date of Patent: November 26, 2013Assignee: Panasonic CorporationInventors: Takao Suzuki, Hisashi Hagiwara, Yoshinao Tannaka, Yoshinobu Watanabe
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Publication number: 20130273487Abstract: In a sample heating method which uses a microchip, using the microchip which includes a vessel portion (70e) in which at least a portion is configured of an elastic member and a flow channel (61b) which leads a liquid sample to the vessel portion (70e), after a liquid sample is put in the vessel portion (70e), the liquid sample is heated while pressure is applied with respect to an inner portion of the vessel portion (70e).Type: ApplicationFiled: December 19, 2011Publication date: October 17, 2013Applicant: NEC CORPORATIONInventors: Minoru Asogawa, Hisashi Hagiwara