Abstract: A switch device includes a plurality of communication ports; a switch unit configured to relay a frame, which has been transmitted from a function unit and to which information including an ID of a VLAN is added, to another function unit via a communication port; and a duplication unit configured to, when the diagnosis device is connected to another switch device, duplicate the frame to be relayed via a designated communication port among the plurality of communication ports, and generate a duplicate frame for diagnosis that is a frame obtained by adding, to a duplicate frame obtained through the duplication, specific information indicating that the duplicate frame for diagnosis should be transmitted to the diagnosis device. The switch unit outputs the duplicate frame for diagnosis generated by the duplication unit from a communication port corresponding to the other switch device.

Abstract: In a writing tool 1, a front shaft 5 is detachably provided on a rear shaft 6 containing an ink absorbent body 7. A filling part 51 is provided on an outside surface of a rear part of the front shaft 5. The filling part 51 detachably fits to a fitted part 61 formed on an inside surface of an opening part of the rear shaft 6. The filling part 51 has an outward-facing pressure contact part 53 and a radially penetrating slit 54. The fitted part 61 has an inward-facing pressure contact part 63. The front shaft 5 and the rear shaft 6 are brought into a pressure contact with each other when the front shaft 5 and the rear shaft 6 are fitted to each other.

Abstract: In a writing tool 1, a front shaft 5 is detachably provided on a rear shaft 6 containing an ink absorbent body 7. A filling part 51 is provided on an outside surface of a rear part of the front shaft 5. The filling part 51 detachably fits to a fitted part 61 formed on an inside surface of an opening part of the rear shaft 6. The filling part 51 has an outward-facing pressure contact part 53 and a radially penetrating slit 54. The fitted part 61 has an inward-facing pressure contact part 63. The front shaft 5 and the rear shaft 6 are brought into a pressure contact with each other when the front shaft 5 and the rear shaft 6 are fitted to each other.

Abstract: The outer surface of an inner cap 3 is fixedly secured to the inner surface of an outer cap 4. In the opened end portion of the inner cap 3, there is formed a rear end shell portion 31 which projects backwardly. On the outer peripheral surface of the rear end shell portion 31, there is provided a ring-shaped outward facing seal portion. In the front end portion of a barrel 6, there is formed a front end shell portion 61 projecting forwardly. In the inner peripheral surface of the front end shell portion 61, there is formed a ring-shaped inward facing seal portion. When a cap 2 is mounted on the pen tip 8 side of the barrel 6, the outward facing seal portion can be closely contacted with the inward facing seal portion in the radial direction.

Abstract: The outer surface of an inner cap 3 is fixedly secured to the inner surface of an outer cap 4. In the opened end portion of the inner cap 3, there is formed a rear end shell portion 31 which projects backwardly. On the outer peripheral surface of the rear end shell portion 31, there is provided a ring-shaped outward facing seal portion. In the front end portion of a barrel 6, there is formed a front end shell portion 61 projecting forwardly. In the inner peripheral surface of the front end shell portion 61, there is formed a ring-shaped inward facing seal portion. When a cap 2 is mounted on the pen tip 8 side of the barrel 6, the outward facing seal portion can be closely contacted with the inward facing seal portion in the radial direction.

Abstract: Provided is a method of treating humans or animals suffering from a condition or disease characterized by excessive collagen destruction, which comprises administering to said human or animal an effective amount of a 12a-deoxytetracycline represented by the following general formula ##STR1## The method is effective in the treatment of various articular diseases characterized by excessive collagen destruction.

Abstract: A method for diagnosing rheumatoid arthritis, which is characterized by enzyme-immunologically measuring the amount of collagenase inhibitor present in sera, plasmas or synovial fluids by way of a sandwich assay wherein two different monoclonal antibodies which specifically bind to different antigenic determinants of the collagenase inhibitor are used, and comparing the measured amount with that for normal subjects.

Abstract: A biocompatible composite material comprising a substrate having a glass-hydroxyapatite ceramic layer disposed thereon, and optionally having an intermediate glass layer between the substrate and the layer. The glass-hydroxyapatite ceramic layer comprises a continuous glass phase having a hydroxyapatite ceramic dispersed therein, said hydroxyapatite ceramic having a calcium/phosphorous molar ratio of 1.50 to 1.75, wherein said hydroxyapatite ceramic is comprised mainly of hydroxyapatite. The surface portion of the layer is in a roughened state having voids and having the hydroxyapatite ceramic exposed. The composite material may be produced by a method comprising applying a blend of a powdery glass with a hydroxyapatite ceramic to the surface of a substrate with or without a glass layer disposed thereon, firing the resulting coated substrate and subjecting the fired coated substrate to an etching action with an acid.