Patents by Inventor Hisashi Shibata
Hisashi Shibata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220294442Abstract: A drive circuit is provided. When the switching element is in turn-on state and a collector-emitter voltage of the switching element is equal to or higher than a first predetermined voltage value, the first diode is turned on; the first transistor and the second transistor are turned on; and, after a mask time in which a first capacitor is started to be charged with a current from a current source and a voltage value at two ends becomes equal to or higher than a second predetermined voltage value higher than the first predetermined voltage value, an abnormality detection signal is output to the control unit. The control unit stops an output of the pulse signal to the switching element in response to the abnormality detection signal.Type: ApplicationFiled: February 17, 2022Publication date: September 15, 2022Applicant: TAMURA CORPORATIONInventors: Hisashi Shibata, Tomohiko Yoshino, Hiroo Ogawa
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Patent number: 8431603Abstract: A compound represented by the following formula (I), or salt thereof exhibits excellent CRF receptor antagonism, and sufficient pharmacological activity, safety and pharmacokinetic properties as a drug. wherein R1 represents the formula -A11-A12; R2 represents tetrahydrofurylmethyl, tetrahydropyranylmethyl or tetrahydropyranyl; A11 represents a single bond, methylene or 1,2-ethylene; A12 represents C1-6 alkyl, C3-6 cycloalkyl or C3-6 cycloalkyl having methyl; R3 represents methoxy, cyano, cyclobutyloxymethyl, methoxymethyl or ethoxymethyl; and R4 represents methoxy or chlorine.Type: GrantFiled: April 9, 2009Date of Patent: April 30, 2013Assignee: Eisai R&D Management Co., Ltd.Inventors: Hisashi Shibata, Kodo Shikata, Akira Inomata, Kogyoku Shin, Taro Terauchi, Yoshinori Takahashi, Minako Hashizume, Kunitoshi Takeda
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Patent number: 7772249Abstract: The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula or a salt thereof. Wherein R1 denotes a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group and the like; R2 denotes a halogen atom, a cyano group, a nitro group, a C1-10 alkyl group, a C2-10 alkenyl group, C2-10 alkynyl group and the like; R3 denotes a C6-14 aromatic hydrocarbon cyclic group or a 5- to 14-membered aromatic heterocyclic group, each of which may have a substituent; and X, Y and X are independent of each other and each denotes N or CR4 (wherein R4 denotes a hydrogen atom, a halogen atom, a cyano group, a nitro group, an optionally halogenated C1-6 alkyl group and the like) and, in this case, at least two of X, Y and Z denote CR4.Type: GrantFiled: March 3, 2009Date of Patent: August 10, 2010Assignee: Eisai R&D Management Co., Ltd.Inventors: Shigeki Hibi, Yoshinori Takahashi, Yorihisa Hoshino, Koichi Kikuchi, Motohiro Soejima, Tatsuya Yoshiuchi, Kogyoku Shin, Mutsuko Ono, Hisashi Shibata, Mitsuhiro Ino, Tetsuya Hirakawa
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Patent number: 7625925Abstract: Compounds represented by the general formula: [wherein R1 represents methoxy, ethyl, methylthio, etc., R2, R3 and R4 each represent hydrogen, a halogen, etc., R5 and R6 each represent —X5—X6—X7 (wherein X5 represents a single bond or —CO—, X6 represents a single bond, —NR3a, etc. and X7 and R3a each represent hydrogen, C1-10 alkyl, etc.), and Ar represents phenyl, pyridyl, etc.], salts thereof and hydrates of the foregoing.Type: GrantFiled: June 4, 2007Date of Patent: December 1, 2009Assignee: Eisai R&D Management Co., LtdInventors: Shigeki Hibi, Koichi Kikuchi, Yorihisa Hoshino, Motohiro Soejima, Tatsuya Yoshiuchi, Kogyoku Shin, Mutsuko Ono, Yoshinori Takahashi, Hisashi Shibata, Mitsuhiro Ino, Tetsuya Hirakawa
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Publication number: 20090259049Abstract: A compound represented by the following formula (I), or salt thereof exhibits excellent CRF receptor antagonism, and sufficient pharmacological activity, safety and pharmacokinetic properties as a drug. wherein R1 represents the formula -A11-A12; R2 represents tetrahydrofurylmethyl, tetrahydropyranylmethyl or tetrahydropyranyl; A11 represents a single bond, methylene or 1,2-ethylene; A12 represents C1-6 alkyl, C3-6 cycloalkyl or C3-6 cycloalkyl having methyl; R3 represents methoxy, cyano, cyclobutyloxymethyl, methoxymethyl or ethoxymethyl; and R4 represents methoxy or chlorine.Type: ApplicationFiled: April 9, 2009Publication date: October 15, 2009Applicant: Eisai R & D Management Co., Ltd.Inventors: Hisashi Shibata, Kodo Shikata, Akira Inomata, Kogyoku Shin, Taro Terauchi, Yoshinori Takahashi, Minako Hashizume, Kunitoshi Takeda
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Publication number: 20090181985Abstract: The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula or a salt thereof. Wherein R1 denotes a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group and the like; R2 denotes a halogen atom, a cyano group, a nitro group, a C1-10 alkyl group, a C2-10 alkenyl group, C2-10 alkynyl group and the like; R3 denotes a C6-14 aromatic hydrocarbon cyclic group or a 5- to 14-membered aromatic heterocyclic group, each of which may have a substituent; and X, Y and X are independent of each other and each denotes N or CR4 (wherein R4 denotes a hydrogen atom, a halogen atom, a cyano group, a nitro group, an optionally halogenated C1-6 alkyl group and the like) and, in this case, at least two of X, Y and Z denote CR4.Type: ApplicationFiled: March 3, 2009Publication date: July 16, 2009Applicant: Eisai R&D Management Co., Ltd.Inventors: Shigeki Hibi, Yoshinori Takahashi, Yorihisa Hoshino, Koichi Kikuchi, Motohiro Soejima, Tatsuya Yoshiuchi, Kogyoku Shin, Matsuko Ono, Hisashi Shibata, Mitsuhiro Ino, Tetsuya Hirakawa
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Patent number: 7530748Abstract: A camera module is composed from a lens unit including at least one lens, a barrel provided with the lens and having a barrel opening, and a lens holder for holding the barrel; and an image pickup device portion provided under the lens unit and having an image pickup device housing space in which an image pickup device is hermetically provided. The barrel opening of the barrel has an annular edge which serves as a diaphragm, and the annular edge of the barrel opening has a lower annular corner portion which is located on the side of the lens, wherein the lower annular corner portion of the annular edge is formed so as to have a rounded cross-sectional shape and staining is formed on the lower annular corner portion.Type: GrantFiled: July 28, 2006Date of Patent: May 12, 2009Assignee: Mitsumi Electric Co., Ltd.Inventors: Hisashi Shibata, Toshihiko Sato
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Patent number: 7428111Abstract: A camera module has a lens unit and an image pickup portion. The lens unit has at least one lens and a lens holder for holding the lens. The image pickup portion, which is provided below the lens unit, has a substrate, an image pickup device mounted on the substrate, a housing space for housing the image pickup device therein in a hermetically sealed state, and a base provided above the substrate. The base has an opening for introducing light passing through the lens to the image pickup device, a support portion located around the opening, and a recessed groove located around the support portion for holding a resin adhesive for bonding. The image pickup portion also has a filter having a peripheral portion bonded to an upper surface of the support portion so as to cover the opening.Type: GrantFiled: July 28, 2006Date of Patent: September 23, 2008Assignee: Mitsumi Electric Co., Ltd.Inventors: Hisashi Shibata, Toshihiko Sato
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Publication number: 20080076943Abstract: A compound represented by the formula: [wherein R1 is methoxy, methylthio, ethyl, etc.; R5 and R6 are each independently cyclopropylmethyl, (4-tetrahydropyranyl)methyl, etc.; and two of R40, R41 and R42 are C1-6 alkoxy while the remaining one is methoxymethyl, etc.], a salt thereof, or a hydrate of the foregoing. This compound has excellent antagonism against corticotropin-releasing factor receptor.Type: ApplicationFiled: September 20, 2007Publication date: March 27, 2008Inventors: Shigeki HIBI, Yorihisa HOSHINO, Koichi KIKUCHI, Kogyoku SHIN, Yoshinori TAKAHASHI, Masae FUJISSAWA, Hisashi SHIBATA, Mitsuhiro INO
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Patent number: 7323569Abstract: A compound represented by the formula: [wherein R1 is methoxy, methylthio, ethyl, etc.; R5 and R6 are each independently cyclopropylmethyl, (4-tetrahydropyranyl)methyl, etc.; and two of R40, R41 and R42 are C1-6 alkoxy while the remaining one is methoxymethyl, etc.], a salt thereof, or a hydrate of the foregoing. This compound has excellent antagonism against corticotropin-releasing factor receptor.Type: GrantFiled: October 22, 2003Date of Patent: January 29, 2008Assignee: Eisai R&D Management Co., Ltd.Inventors: Shigeki Hibi, Yorihisa Hoshino, Koichi Kikuchi, Kogyoku Shin, Yoshinori Takahashi, Masae Fujisawa, Hisashi Shibata, Mitsuhiro Ino
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Publication number: 20070249663Abstract: Compounds represented by the general formula: [wherein R1 represents methoxy, ethyl, methylthio, etc., R2, R3 and R4 each represent hydrogen, a halogen, etc., R5 and R6 each represent —X5—X6—X7 (wherein X5 represents a single bond or —CO—, X6 represents a single bond, —NR3a, etc. and X7 and R3a each represent hydrogen, C1-10 alkyl, etc.), and Ar represents phenyl, pyridyl, etc.], salts thereof and hydrates of the foregoing.Type: ApplicationFiled: June 4, 2007Publication date: October 25, 2007Inventors: Shigeki Hibi, Koichi Kikuchi, Yorihisa Hoshino, Motohiro Soejima, Tatsuya Yoshiuchi, Kogyoku Shin, Mutsuko Ono, Yoshinori Takahashi, Hisashi Shibata, Mitsuhiro Ino, Tetsuya Hirakawa
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Patent number: 7285666Abstract: Compounds represented by the general formula: [wherein R1 represents methoxy, ethyl, methylthio, etc., R2, R3 and R4 each represent hydrogen, a halogen, etc., R5 and R6 each represent —X5—X6—X7 (wherein X5 represents a single bond or —CO—, X6 represents a single bond, —NR3a, etc. and X7 and R3a each represent hydrogen, C1-10 alkyl, etc.), and Ar represents phenyl, pyridyl, etc.], salts thereof and hydrates of the foregoing.Type: GrantFiled: June 5, 2006Date of Patent: October 23, 2007Assignee: Eisai R&D Management Co., Ltd.Inventors: Shigeki Hibi, Koichi Kikuchi, Yorihisa Hoshino, Motohiro Soejima, Tatsuya Yoshiuchi, Kogyoku Shin, Mutsuko Ono, Yoshinori Takahashi, Hisashi Shibata, Mitsuhiro Ino, Tetsuya Hirakawa
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Patent number: 7189717Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2 receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.Type: GrantFiled: April 26, 2001Date of Patent: March 13, 2007Assignee: Eisai Co., Ltd.Inventors: Masahiro Yasuda, Hitoshi Harada, Shuhei Miyazawa, Seiichi Kobayashi, Kokichi Harada, Takayuki Hida, Hisashi Shibata, Nobuyuki Yasuda, Osamu Asano, Yoshihiko Kotake
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Publication number: 20070053685Abstract: A camera module is composed from a lens unit including at least one lens, a barrel provided with the lens and having a barrel opening, and a lens holder for holding the barrel; and an image pickup device portion provided under the lens unit and having an image pickup device housing space in which an image pickup device is hermetically provided. The barrel opening of the barrel has an annular edge which serves as a diaphragm, and the annular edge of the barrel opening has a lower annular corner portion which is located on the side of the lens, wherein the lower annular corner portion of the annular edge is formed so as to have a rounded cross-sectional shape and staining is formed on the lower annular corner portion.Type: ApplicationFiled: July 28, 2006Publication date: March 8, 2007Inventors: Hisashi Shibata, Toshihiko Sato
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Publication number: 20070054876Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2 receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.Type: ApplicationFiled: November 8, 2006Publication date: March 8, 2007Inventors: Masahiro Yasuda, Hitoshi Harada, Shuhei Miyazawa, Seiichi Kobayashi, Kokichi Harada, Takayuki Hida, Hisashi Shibata, Nobuyuki Yasuda, Osamu Asano, Yoshihiko Kotake
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Publication number: 20070047109Abstract: A camera module has a lens unit and an image pickup portion. The lens unit has at least one lens and a lens holder for holding the at least one lens. The image pickup portion is provided below the lens unit. The image pickup portion has a substrate, an image pickup device mounted on the substrate, a housing space for housing the image pickup device therein in a hermetically sealed state, and a base provided above the substrate. The base has an opening for introducing light passing through the at least one lens to the image pickup device in the housing space, a support portion located around the opening, and a recessed groove located around the support portion for holding a resin adhesive for bonding. The image pickup portion also has a filter having a peripheral portion bonded to an upper surface of the support portion so as to cover the opening of the base.Type: ApplicationFiled: July 28, 2006Publication date: March 1, 2007Inventors: Hisashi Shibata, Toshihiko Sato
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Patent number: 7176216Abstract: A compound represented by the formula: [wherein R1 is methoxy, methylthio, ethyl, etc.; R5 and R6 are each independently cyclopropylmethyl, (4-tetrahydropyranyl)methyl, etc.; and two of R40, R41 and R42 are C1-6 alkoxy while the remaining one is methoxymethyl, etc.], a salt thereof, or a hydrate of the foregoing. This compound has excellent antagonism against corticotropin-releasing factor receptor.Type: GrantFiled: October 21, 2003Date of Patent: February 13, 2007Assignee: Eisai Co., Ltd.Inventors: Shigeki Hibi, Yorihisa Hoshino, Koichi Kikuchi, Kogyoku Shin, Yoshinori Takahashi, Masae Fujisawa, Hisashi Shibata, Mitsuhiro Ino
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Publication number: 20060270674Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.Type: ApplicationFiled: August 9, 2006Publication date: November 30, 2006Inventors: Masahiro Yasuda, Hitoshi Harada, Shuhei Miyazawa, Seiichi Kobayashi, Kokichi Harada, Takayuki Hida, Hisashi Shibata, Nobuyuki Yasuda, Osamu Asano, Yoshihiko Kotake
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Publication number: 20060235011Abstract: A compound represented by the formula: [wherein R1 is methoxy, methylthio, ethyl, etc.; R5 and R6 are each independently cyclopropylmethyl, (4-tetrahydropyranyl)methyl, etc.; and two of R40, R41 and R42 are C1-6 alkoxy while the remaining one is methoxymethyl, etc.], a salt thereof, or a hydrate of the foregoing. This compound has excellent antagonism against corticotropin-releasing factor receptor.Type: ApplicationFiled: October 22, 2003Publication date: October 19, 2006Applicant: Eisai Co.Ltd.Inventors: Shigeki Hibi, Yorihisa Hoshino, Koichi Kikuchi, Kyogyoku Shin, Yoshinori Takahashi, Masae Fujisawa, Hisashi Shibata, Mitsuhiro Ino
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Publication number: 20060217348Abstract: Compounds represented by the general formula: [wherein R1 represents methoxy, ethyl, methylthio, etc., R2, R3 and R4 each represent hydrogen, a halogen, etc., R5 and R6 each represent —X5—X6—X7 (wherein X5 represents a single bond or —CO—, X6 represents a single bond, —NR3a, etc. and X7 and R3a each represent hydrogen, C1-10 alkyl, etc.), and Ar represents phenyl, pyridyl, etc.], salts thereof and hydrates of the foregoing.Type: ApplicationFiled: June 5, 2006Publication date: September 28, 2006Inventors: Shigeki Hibi, Koichi Kikuchi, Yorihisa Hoshino, Motohiro Soejima, Tatsuya Yoshiuchi, Kogyoku Shin, Mutsuko Ono, Yoshinori Takahashi, Hisashi Shibata, Mitsuhiro Ino, Tetsuya Hirakawa