Patents by Inventor Hisashi Tamaoka

Hisashi Tamaoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for inhibiting cytokine secretion
    Patent number: 6034100
    Abstract: A method for the prophylaxis and treatment of diseases induced by acceleration of secretion of cytokines (e.g. TNF-.alpha., IL-1, IL-6, IL-8, and IFN-.gamma.) which comprises administering a benzoheterocyclic compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are lower alkyl and X.sup.1 is halogen, R.sup.3 is lower alkyl, R.sup.4 is hydroxy, and X.sup.2 is halogen, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 5, 1995
    Date of Patent: March 7, 2000
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Masakazu Adachi, Hisashi Tamaoka, Yukihisa Ono, Kazunori Omori
  • Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
    Patent number: 5376686
    Abstract: The invention presents a biguanide derivative or its salt expressed by a formula: ##STR1## (where R.sup.1 and R.sup.2 are as defined in Specification), or formula: ##STR2## (where A and R.sup.3 is as defined in specification). This biguanide derivative or its salt is preferably used as the effective amount of a disinfectant for humans, animals, medical appliances, etc.
    Type: Grant
    Filed: April 3, 1992
    Date of Patent: December 27, 1994
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Ishikawa, Koichi Yasumura, Hidetsugu Tsubouchi, Yukio Higuchi, Hisashi Tamaoka