Patents by Inventor Hisashi Wakita

Hisashi Wakita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11660275
    Abstract: Provided is a combination agent that combines N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide with an AMPA-type glutamate receptor antagonist such as 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one or 2-fluoro-6-(3-fluoro-8-oxo-7-(pyridin-3-yl)-7,8-dihydro-6H-pyrano[3,2-b:5,4-b?]dipyridin-9-yl)benzonitrile, and it has potential for use as a therapeutic agent for epilepsy.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: May 30, 2023
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Hiroyuki Higashiyama, Hisashi Wakita, Yoshimasa Ito, Yoshihide Osada
  • Publication number: 20210000771
    Abstract: Provided is a combination agent that combines N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide with an AMPA-type glutamate receptor antagonist such as 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one or 2-fluoro-6-(3-fluoro-8-oxo-7-(pyridin-3-yl)-7,8-dihydro-6H-pyrano[3,2-b:5,4-b?]dipyridin-9-yl)benzonitrile, and it has potential for use as a therapeutic agent for epilepsy.
    Type: Application
    Filed: March 18, 2019
    Publication date: January 7, 2021
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Hiroyuki Higashiyama, Hisashi Wakita, Yoshimasa Ito, Yoshihide OSADA
  • Publication number: 20200383959
    Abstract: A compound represented by formula (I) or a pharmaceutically acceptable salt thereof has potential use as an agent for treating essential tremor, small fiber neuropathy, dystonia, epilepsy associated with Alzheimer's disease, epilepsy associated with brain tumor, or brain tumor.
    Type: Application
    Filed: May 7, 2018
    Publication date: December 10, 2020
    Inventors: Katsutoshi Ido, Hisashi Wakita, Ken Hatanaka
  • Patent number: 7939540
    Abstract: A compound represented by the following formula (I), salt thereof, or hydrate thereof, can effectively relieve itch caused by atopic disease or the like: wherein R represents hydroxyl, C1-6 alkoxy optionally substituted with C1-6 alkoxy, or amino optionally substituted with C1-6 alkyl.
    Type: Grant
    Filed: February 20, 2007
    Date of Patent: May 10, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Kazuki Miyazaki, Kazutomi Kusano, Yasutaka Takase, Osamu Asano, Manabu Shirato, Hisashi Wakita, Naoto Ishii, Takao Saeki, Tomoko Saeki, legal representative, Mai Saeki, legal representative
  • Publication number: 20070299094
    Abstract: A compound represented by the following formula (I), salt thereof, or hydrate thereof, can effectively relieve itch caused by atopic disease or the like: wherein R represents hydroxyl, C1-6 alkoxy optionally substituted with C1-6 alkoxy, or amino optionally substituted with C1-6 alkyl.
    Type: Application
    Filed: February 20, 2007
    Publication date: December 27, 2007
    Inventors: Kazuki Miyazaki, Kazutomi Kusano, Yasutaka Takase, Osamu Asano, Manabu Shirato, Hisashi Wakita, Naoto Ishii, Takao Saeki, Tomoko Saeki, Mai Saeki
  • Patent number: 5696878
    Abstract: A speaker normalization method is described based on spectral shifts in the auditory filter domain. The method is characterized by using an estimated vocal tract length as a criterion to determine the spectral shift value. Certain constraints are found to be necessary for the shift in the auditory filter domain, and two techniques based on these constraints, the One-Bark shift and the refined Bark-scale shift, are introduced. When tested in vowel classification experiments, significant performance improvement was obtained for both techniques. The method is useful for speaker normalization in speaker-independent speech recognition.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: December 9, 1997
    Assignee: Panasonic Technologies, Inc.
    Inventors: Yoshio Ono, Yunxin Zhao, Hisashi Wakita