Patents by Inventor Hisatoshi Shinagawa

Hisatoshi Shinagawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • &bgr;-lactam compounds and process for producing the same
    Patent number: 6599895
    Abstract: Novel &bgr;-lactam compound of the formula [1]: wherein R1 is lower alkyl or hydroxy-substituted lower alkyl, R2 is H or lower alkyl, X is O or, S, R3 is H, metal or protecting group, W is a 6- or 7-membered nitrogen-containing heterocycle optionally being substituted at carbon atoms. Said &bgr;-lactam compound shows excellent antibacterial activity against Gram-positive bacteria, particularly against methicillin-resistant Staphylococcus aureus and methicillin-resistant and coagulase-negative Staphylococcus aureus.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: July 29, 2003
    Assignee: Sumitomo Pharmaceuticals Company, Limited
    Inventors: Makoto Sunagawa, Hiroshi Yamaga, Yoshihiro Sumita, Hisatoshi Shinagawa
  • &bgr;-lactam compounds and process for preparing the same
    Patent number: 6265396
    Abstract: A &bgr;-lactam compound of the formula: wherein R1 is lower alkyl or OH-substituted lower alkyl, R2 is H or lower alkyl, X is O, S or NH, n is 1 to 3, R3 is —C(Ra)═NH (Ra is H, lower alkyl or substituted lower alkyl), or a salt thereof, or an ester thereof. These compounds show excellent antibacterial activity against Gram-positive bacteria, particularly against methicillin-resistant Staphylococci and methicillin-resistant and coagulase-negative Staphylococci.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: July 24, 2001
    Assignee: Sumitomo Pharmaceuticals Co., Ltd.
    Inventors: Makoto Sunagawa, Hiroshi Yamaga, Hiroshi Nouda, Hisatoshi Shinagawa