Patents by Inventor Hiten Sharadchandra Mehta

Hiten Sharadchandra Mehta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of crystalline aprepitant having form I content
    Patent number: 8816072
    Abstract: The present invention provides a process for preparation of crystalline aprepitant having not more than 15% by weight of Form I content which comprises, a) dissolving aprepitant in a suitable solvent to obtain a solution, b) cooling the solution to 10-15° C., c) optionally seeding the solution with aprepitant Form I crystals, d) adding an anti-solvent to the solution, and e) isolating crystalline aprepitant having not more than 15% by weight of Form I content.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: August 26, 2014
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Deepak Mohanlal Jain, Maneck Khurana, Hiten Sharadchandra Mehta, Abhay Tatiya, Asok Nath, Sanjay Mahadeo Gade, Mohan Prasad, Subhash Dhar
  • PROCESS FOR THE PREPARATION OF CRYSTALLINE APREPITANT HAVING FORM I CONTENT
    Publication number: 20120277426
    Abstract: The present invention provides a process for preparation of crystalline aprepitant having not more than 15% by weight of Form I content which comprises, a) dissolving aprepitant in a suitable solvent to obtain a solution, b) cooling the solution to 10-15° C., c) optionally seeding the solution with aprepitant Form I crystals, d) adding an anti-solvent to the solution, and e) isolating crystalline aprepitant having not more than 15% by weight of Form I content.
    Type: Application
    Filed: June 2, 2010
    Publication date: November 1, 2012
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Deepak Mohanlal Jain, Maneck Khurana, Hiten Sharadchandra Mehta, Abhay Tatiya, Asok Nath, Sanjay Mahadeo Gade, Mohan Prasad, Subhash Dhar
  • POLYMORPHIC FORM OF OLMESARTAN MEDOXOMIL
    Publication number: 20120184751
    Abstract: The present invention relates to a polymorphic form of olmesartan medoxomil and a process for the preparation of crystalline olmesartan medoxomil.
    Type: Application
    Filed: July 29, 2010
    Publication date: July 19, 2012
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Ashwini Kumar Kapoor, Hiten Sharadchandra Mehta, Asok Nath, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL
    Publication number: 20120184750
    Abstract: The present invention provides an improved process for the preparation of olmesartan medoxomil, which is free of OLM-acid and has lower amount of eliminate and acetic acid impurity.
    Type: Application
    Filed: May 20, 2010
    Publication date: July 19, 2012
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Ashwini Kumar Kapoor, Hiten Sharadchandra Mehta, Asok Nath, Mohan Prasad
  • Process for the preparation of aprepitant
    Patent number: 8080656
    Abstract: The present invention relates to a highly pure (2R,3S)-4-benzyl-3-(4-fluorophenyl)morpholin-2-yl 3,5-bis(trifluoromethyl)benzoate of Formula II, and a process for its preparation. The present invention further provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof, using the highly pure compound of Formula II. The present invention also provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof which comprises of cyclising the compound of Formula VII at elevated temperature, in the absence of solvent.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: December 20, 2011
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Asok Nath, Hiten Sharadchandra Mehta, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF APREPITANT
    Publication number: 20100004242
    Abstract: The present invention relates to a highly pure (2R,3S)-4-benzyl-3-(4-fluorophenyl)morpholin-2-yl 3,5-bis(trifluoromethyl)benzoate of Formula II, and a process for its preparation. The present invention further provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof, using the highly pure compound of Formula II. The present invention also provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof which comprises of cyclising the compound of Formula VII at elevated temperature, in the absence of solvent.
    Type: Application
    Filed: October 5, 2006
    Publication date: January 7, 2010
    Inventors: Asok Nath, Hiten Sharadchandra Mehta, Mohan Prasad