Patents by Inventor Hitesh Kumar Agarwal

Hitesh Kumar Agarwal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted nucleoside derivatives with antiviral and antimicrobial properties
    Patent number: 9738678
    Abstract: The present invention relates to fatty acid and fatty alcohol substituted nucleoside derivatives and nucleoside and nucleoside derivatives substituted on multivalent scaffolds (e.g., polymers, peptides, polycarboxylic acid substituted compounds, compounds containing polycycloSaligenyl groups) that display potent anti-HIV activity. Furthermore, they show enhanced activity against multi-drug resistant, R5, and cell-associated virus. Some of them also display activity against other sexually transmitted pathogens and sperm. The present invention provides their methods of synthesis, composition of matter, and methods of use. Emphasis is placed on their application as topical microbicides to treat or prevent sexual transmission of disease, especially HIV/AIDS.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: August 22, 2017
    Assignees: Eastern Virginia Medical School, Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
    Inventors: Gustavo F. Doncel, Keykavous Parang, Hitesh Kumar Agarwal
  • SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES
    Publication number: 20160311843
    Abstract: The present invention relates to fatty acid and fatty alcohol substituted nucleoside derivatives and nucleoside and nucleoside derivatives substituted on multivalent scaffolds (e.g., polymers, peptides, polycarboxylic acid substituted compounds, compounds containing polycycloSaligenyl groups) that display potent anti-HIV activity. Furthermore, they show enhanced activity against multi-drug resistant, R5, and cell-associated virus. Some of them also display activity against other sexually transmitted pathogens and sperm. The present invention provides their methods of synthesis, composition of matter, and methods of use. Emphasis is placed on their application as topical microbicides to treat or prevent sexual transmission of disease, especially HIV/AIDS.
    Type: Application
    Filed: March 24, 2016
    Publication date: October 27, 2016
    Applicants: Eastern Virginia Medical School, Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
    Inventors: Gustavo F. DONCEL, Keykavous PARANG, Hitesh Kumar AGARWAL
  • Substituted nucleoside derivatives with antiviral and antimicrobial properties
    Patent number: 9296776
    Abstract: The present invention relates to fatty acid and fatty alcohol substituted nucleoside derivatives and nucleoside and nucleoside derivatives substituted on multivalent scaffolds (e.g., polymers, peptides, polycarboxylic acid substituted compounds, compounds containing polycycloSaligenyl groups) that display potent anti-HIV activity. Furthermore, they show enhanced activity against multi-drug resistant, R5, and cell-associated virus. Some of them also display activity against other sexually transmitted pathogens and sperm. The present invention provides their methods of synthesis, composition of matter, and methods of use. Emphasis is placed on their application as topical microbicides to treat or prevent sexual transmission of disease, especially HIV/AIDS.
    Type: Grant
    Filed: July 9, 2008
    Date of Patent: March 29, 2016
    Assignees: Eastern Virginia Medical School, Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
    Inventors: Gustavo F. Doncel, Keykavous Parang, Hitesh Kumar Agarwal
  • SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES
    Publication number: 20110039798
    Abstract: The present invention relates to fatty acid and fatty alcohol substituted nucleoside derivatives and nucleoside and nucleoside derivatives substituted on multivalent scaffolds (e.g., polymers, peptides, polycarboxylic acid substituted compounds, compounds containing polycycloSaligenyl groups) that display potent anti-HIV activity. Furthermore, they show enhanced activity against multi-drug resistant, R5, and cell-associated virus. Some of them also display activity against other sexually transmitted pathogens and sperm. The present invention provides their methods of synthesis, composition of matter, and methods of use. Emphasis is placed on their application as topical microbicides to treat or prevent sexual transmission of disease, especially HIV/AIDS.
    Type: Application
    Filed: July 9, 2008
    Publication date: February 17, 2011
    Applicant: EASTERN VIRGINIA MEDICAL SCHOOL
    Inventors: Gustavo F. Doncel, Keykavous Parang, Hitesh Kumar Agarwal