Patents by Inventor Hitesh N. Shroff

Hitesh N. Shroff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor
    Publication number: 20020103111
    Abstract: The present invention provides novel compounds comprising peptide sequences which mimic the conserved amino acid motif LDTSL of MAdCAM-1 and which have groups bonded to the N- and C-termini. Also provided are methods of inhibiting the interaction of a cell bearing a ligand of MAdCAM-1, such as human &agr;4&bgr;7, with MAdCAM-1 or a portion thereof (e.g., the extracellular domain), comprising contacting the cell with a compound of the present invention.
    Type: Application
    Filed: May 16, 2001
    Publication date: August 1, 2002
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Charles F. Schwender, Hitesh N. Shroff
  • Inhibitors of MadCAM-1-mediated interactions and methods of use therefor
    Patent number: 6274556
    Abstract: The present invention provides novel compounds comprising peptide sequences which mimic the conserved amino acid motif LDTSL of MAdCAM-1 and which have groups bonded to the N- and C-termini. Also provided are methods of inhibiting the interaction of a cell bearing a ligand of MAdCAM-1, such as human &agr;4&bgr;7, with MAdCAM-1 or a portion thereof (e.g., the extracellular domain), comprising contacting the cell with a compound of the present invention.
    Type: Grant
    Filed: July 2, 1998
    Date of Patent: August 14, 2001
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Charles F. Schwender, Hitesh N. Shroff
  • Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor
    Patent number: 6037324
    Abstract: The present invention provides novel compounds comprising peptide sequences which mimic the conserved amino acid motif LDTSL and which have groups bonded to the N- and C-termini. Also provided are methods of inhibiting the interaction of a cell bearing a ligand of MAdCAM-1, such as human .alpha.4.beta.7, with MAdCAM-1 or a portion thereof (e.g., the extracellular domain), comprising contacting the cell with a compound of the present invention.
    Type: Grant
    Filed: January 4, 1996
    Date of Patent: March 14, 2000
    Assignee: LeukoSite, Inc.
    Inventors: Charles F. Schwender, Hitesh N. Shroff