Patents by Inventor Hitesh Sanganee

Hitesh Sanganee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR DIGITAL PREDICTIVE DISEASE EXACERBATION AND PRE-EMPTIVE TREATMENT
    Publication number: 20160089089
    Abstract: The system described herein collects patient data passively and non-passively via onboard and external sensors, and combines the data with past clinical history to generate digital biomarkers. The collected data can also be further combined with other data generating systems to more accurately predict disease exacerbations. The system monitors the digital biomarkers in real-time, and can detect a change in the disease state prior to clinical decompensation and suggest pre-emptive intervention. The system enables a patient to be treated early in the clinical timeline when the disease exacerbation is at the subclinical level rather than waiting until the disease exacerbation reaches the clinical level. Acting when the exacerbation is at the subclinical level enables preemptive treatment rather than reactive treatment, which is often more cost effective while improving clinical outcomes.
    Type: Application
    Filed: September 24, 2015
    Publication date: March 31, 2016
    Inventors: Rahul Kakkar, Cyan Collier, Hitesh Sanganee
  • Substituted indoles
    Patent number: 8093278
    Abstract: The present invention relates to substituted indoles of formula (I), useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Grant
    Filed: April 28, 2010
    Date of Patent: January 10, 2012
    Assignee: AstraZeneca AB
    Inventors: Timothy Birkinshaw, Roger Bonnert, Tony Cook, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Novel Substituted Indoles
    Publication number: 20100210685
    Abstract: The present invention relates to substituted indoles of formula (I), useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Application
    Filed: April 28, 2010
    Publication date: August 19, 2010
    Inventors: Timothy Birkinshaw, Roger Bonnert, Tony Cook, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Indole-3-Sulphur Derivatives
    Publication number: 20100197756
    Abstract: The present invention relates to substituted indoles useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Application
    Filed: April 12, 2010
    Publication date: August 5, 2010
    Inventors: Roger Bonnert, Mark Dickinson, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Substituted indoles
    Patent number: 7754735
    Abstract: The present invention relates to substituted indoles of formula (I), useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: July 13, 2010
    Assignee: AstraZeneca AB
    Inventors: Timothy Birkinshaw, Roger Bonnert, Tony Cook, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Indole-3-sulphur derivatives
    Patent number: 7723373
    Abstract: The present invention relates to substituted indoles useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: May 25, 2010
    Assignee: AstraZeneca AB
    Inventors: Roger Bonnert, Mark Dickinson, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Piperidine derivatives useful as modulators of chemokine receptor activity
    Patent number: 7517989
    Abstract: The present invention provides a compound of formula (I), wherein: Z is (A) OR (B) and wherein the remaining variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of achemokine (such as CCR3) or H1 mediated disease state.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: April 14, 2009
    Assignee: AstraZeneca AB
    Inventors: Christopher Luckhurst, Matthew Perry, Hitesh Sanganee, Brian Springthorpe
  • Piperidine Derivatives Useful as Modulators of Chemokine Receptor Activity
    Publication number: 20090069325
    Abstract: The present invention relates to the compounds of formula (I): in which: and the remaining variables are defined herein. The present invention also relates to a process for preparing such compounds and use of such compounds in the treatment of a chemokine (such as CCR3) or H1 mediated disease state.
    Type: Application
    Filed: November 10, 2008
    Publication date: March 12, 2009
    Applicant: AstraZeneca AB
    Inventors: Christopher Luckhurst, Matthew Perry, Hitesh Sanganee, Brian Springthorpe
  • Piperidine derivatives useful as modulators of chemokine receptor activity
    Patent number: 7482363
    Abstract: The present invention provides a compound of formula (I), wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a chemokine (such as CCR3) or H1 mediated disease state.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: January 27, 2009
    Assignee: AstraZeneca AB
    Inventors: Hitesh Sanganee, Brian Springthorpe
  • Chemical compounds
    Patent number: 7348341
    Abstract: The invention concerns compounds of formula (I), and their use in therapy, particularly in the modulation of CCR3 activity.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: March 25, 2008
    Assignee: AstraZeneca AB
    Inventors: Hitesh Sanganee, Brian Springthorpe
  • Chemical compounds
    Patent number: 7304077
    Abstract: The invention provides compounds of formula (I): as modulators of chemokine and H1 receptor activity. The compounds are especially useful in the treatment of asthma and rhinitis.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: December 4, 2007
    Assignee: AstraZeneca AB
    Inventors: Hitesh Sanganee, Brian Springthorpe
  • Chemical compounds
    Publication number: 20070179297
    Abstract: The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a chemokine (such as CCR3) or H1 mediated disease state.
    Type: Application
    Filed: April 3, 2007
    Publication date: August 2, 2007
    Inventors: Aaron Rigby, Hitesh Sanganee, Brian Springthorpe, Louise Lawrence
  • Piperidine derivatives and their use as modulators of chemokine (especially CCR3) activity
    Patent number: 7238691
    Abstract: The invention provides a compound of formula (I): T is C(O) or S(O)2; W is CH2, (CH2)2, CH(CH3), CH(CH3)O or cyclopropyl; X is O, CH2, C(O), S, S(O), S(O)2 or NR3; m is 0 or 1; R1 is optionally substituted aryl or optionally substituted heterocyclyl; R2 is alkyl (optionally substituted by OH), cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl; that are modulators of chemokine (especially CCR3) activity and are especially useful for treating asthma and/or rhinitis.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: July 3, 2007
    Assignee: AstraZeneca AB
    Inventors: Hitesh Sanganee, Brian Springthorpe
  • Chemical compounds
    Patent number: 7238811
    Abstract: The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a chemokine (such as CCR3) or H1 mediated disease state.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: July 3, 2007
    Assignee: AstraZeneca AB
    Inventors: Aaron Rigby, Hitesh Sanganee, Brian Springthorpe, Louise Lawrence
  • Chemical compounds
    Patent number: 7179922
    Abstract: The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a chemokine (such as CCR3) or H1 mediated disease state.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: February 20, 2007
    Assignee: AstraZeneca AB
    Inventors: Aaron Rigby, Hitesh Sanganee, Brian Springthorpe, Louise Lawrence
  • Substituted indoles
    Patent number: 7166607
    Abstract: The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: January 23, 2007
    Assignee: AstraZeneca AB
    Inventors: Roger Bonnert, Stephen Brough, Tony Cook, Mark Dickinson, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Indole-3-sulphur derivaties
    Publication number: 20060111426
    Abstract: The present invention relates to substituted indoles useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Application
    Filed: July 15, 2003
    Publication date: May 25, 2006
    Inventors: Roger Bonnert, Mark Dickinson, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Novel substituted indoles
    Publication number: 20050222201
    Abstract: The present invention relates to substituted indoles of formula (I), useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Application
    Filed: May 27, 2003
    Publication date: October 6, 2005
    Inventors: Timothy Birkinshaw, Roger Bonnert, Tony Cook, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Piperidine derivatives useful as modulators of chemokine receptor activity
    Publication number: 20050182094
    Abstract: The present invention provides a compound of formula (I), wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a chemokine (such as CCR3) or H1 mediated disease state.
    Type: Application
    Filed: March 17, 2003
    Publication date: August 18, 2005
    Inventors: Hitesh Sanganee, Brian Springthorpe
  • Piperidine derivatives useful as modulators of chemokine receptor activity
    Publication number: 20050176708
    Abstract: The present invention provides a compound of formula (I), wherein: Z is (A:) OR (B) and wherein the remaining variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of achemokine (such as CCR3) or H1 mediated disease state,
    Type: Application
    Filed: March 17, 2003
    Publication date: August 11, 2005
    Inventors: Christopher Luckhurst, Matthew Perry, Hitesh Sanganee, Brian Springthorpe