Patents by Inventor Hitomi Kajiwara

Hitomi Kajiwara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ?-galactoside-?2,6-sialyltransferase, a gene encoding thereof, and a method for enhancing enzyme activity
    Patent number: 8372617
    Abstract: The present invention provides an extremely useful and novel ?-galactoside-?2,6-sialyltransferase having an optimum reaction pH in a neutral to alkaline range, and a nucleic acid encoding the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant ?-galactoside-?2,6-sialyltransferase.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: February 12, 2013
    Assignee: Japan Tobacco Inc.
    Inventors: Takeshi Yamamoto, Yoshimitsu Takakura, Toshiki Mine, Yoko Hamada, Hitomi Kajiwara, Masako Ichikawa, Hiroshi Tsukamoto
  • Method of binding proteins to carriers by making use of tamavidins
    Patent number: 8343727
    Abstract: The present invention provides a method of binding a protein to a carrier in such a way that the protein is not impaired in its function but can be allowed to act more efficiently than when it is bound directly. The method of the present invention for binding a protein to a carrier comprises: preparing a biotin-bound carrier; preparing a fusion protein having the protein bound to a tamavidin; and binding the protein to the carrier via tamavidin-biotin bonds.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: January 1, 2013
    Assignee: Japan Tobacco Inc.
    Inventors: Yoshimitsu Takakura, Masako Ichikawa, Satoru Usami, Takeshi Yamamoto, Hiroshi Tsukamoto, Hitomi Kajiwara, Naomi Oka
  • NOVEL BETA-GALACTOSIDE-ALPHA2,6-SIALYLTRANSFERASE, A GENE ENCODING THEREOF, AND A METHOD FOR ENHANCING ENZYME ACTIVITY
    Publication number: 20120282659
    Abstract: The present invention provides an extremely useful and novel ?-galactoside-?2,6-sialyltransferase having an optimum reaction pH in a neutral to alkaline range, and a nucleic acid encoding the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant ?-galactoside-?2,6-sialyltransferase.
    Type: Application
    Filed: April 25, 2012
    Publication date: November 8, 2012
    Inventors: Takeshi Yamamoto, Yoshimitsu Takakura, Toshiki Mine, Yoko Hamada, Hitomi Kajiwara, Masako Ichikawa, Hiroshi Tsukamoto
  • NOVEL PROTEIN AND GENE THAT CODES THEREFOR
    Publication number: 20120184016
    Abstract: The present invention provides a novel protein having neuraminidase activity and/or ?-galactoside-?2,6-sialyltransferase activity and a nucleic acid encoding the protein. The present invention further provides a vector containing a nucleic acid encoding the protein, a host cell transformed with the vector, together with a method for producing a recombinant ?-galactoside-?2,6-sialyltransferase. The present invention also provides an antibody specifically recognizing the protein.
    Type: Application
    Filed: June 11, 2010
    Publication date: July 19, 2012
    Inventors: Toshiki Mine, Takeshi Yamamoto, Hitomi Kajiwara, Hiroshi Tsukamoto
  • ?-galactoside-?2,6-sialyltransferase, a gene encoding thereof, and a method for enhancing enzyme activity
    Patent number: 8187853
    Abstract: The present invention provides an extremely useful and novel ?-galactoside-?2,6-sialyltransferase having an optimum reaction pH in a neutral to alkaline range, and a nucleic acid encoding the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant ?-galactoside-?2,6-sialyltransferase.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: May 29, 2012
    Assignee: Japan Tobacco Inc.
    Inventors: Takeshi Yamamoto, Yoshimitsu Takakura, Toshiki Mine, Yoko Hamada, Hitomi Kajiwara, Masako Ichikawa, Hiroshi Tsukamoto
  • METHOD OF BINDING PROTEINS TO CARRIERS BY MAKING USE OF TAMAVIDINS
    Publication number: 20100311076
    Abstract: The present invention provides a method of binding a protein to a carrier in such a way that the protein is not impaired in its function but can be allowed to act more efficiently than when it is bound directly. The method of the present invention for binding a protein to a carrier comprises: preparing a biotin-bound carrier; preparing a fusion protein having the protein bound to a tamavidin; and binding the protein to the carrier via tamavidin-biotin bonds.
    Type: Application
    Filed: August 28, 2008
    Publication date: December 9, 2010
    Inventors: Yoshimitsu Takakura, Masako Ichikawa, Satoru Usami, Takeshi Yamamoto, Hiroshi Tsukamoto, Hitomi Kajiwara, Naomi Oka
  • NOVEL BETA-GALACTOSIDE-a2,6-SIALYLTRANSFERASE, A GENE ENCODING THEREOF, AND A METHOD FOR ENHANCING ENZYME ACTIVITY
    Publication number: 20100112616
    Abstract: The present invention provides an extremely useful and novel ?-galactoside-?2,6-sialyltransferase having an optimum reaction pH in a neutral to alkaline range, and a nucleic acid encoding the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant ?-galactoside-?2,6-sialyltransferase.
    Type: Application
    Filed: March 3, 2008
    Publication date: May 6, 2010
    Applicant: JAPAN TOBACCO INC.
    Inventors: Takeshi Yamamoto, Yoshimitsu Takakura, Toshiki Mine, Yoko Hamada, Hitomi Kajiwara, Masako Ichikawa, Hiroshi Tsukamoto