Patents by Inventor Hitomi Shimizu-Matsuhashi

Hitomi Shimizu-Matsuhashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9730968
    Abstract: [Object] To provide a gene transfer carrier that specifically accumulates only at a disease site even with systemic administration, has a high protein expression rate, and disappears from the disease site accompanying a cure, and a method for the treatment of an ischemic disease using same. [Solution means] The above-mentioned object has been accomplished by providing a gene transfer carrier formed from an anaerobic bacterium that can grow specifically at the site of an ischemic disease and can express at least one type of protein that is useful for the diagnosis or treatment of an ischemic disease, a pharmaceutical composition containing the gene transfer carrier, and a treatment method for an ischemic disease utilizing same.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: August 15, 2017
    Assignee: Anaeropharma Science, Inc.
    Inventors: Yuko Wada, Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki, Hiromi Yonekura
  • Patent number: 9228191
    Abstract: The present invention relates to a novel secretory signal, a novel plasmid containing the secretory signal, a transformed anaerobic bacterium transformed with said plasmid, a gene transfer carrier consisting of said anaerobic bacterium, and a pharmaceutical composition containing said carrier.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: January 5, 2016
    Assignee: Anaeropharma Science, Inc.
    Inventors: Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki
  • Publication number: 20150290259
    Abstract: To provide a gene transfer carrier that specifically accumulates only at a disease site even with systemic administration, has a high protein expression rate, and disappears from the disease site accompanying a cure, and a method for the treatment of an ischemic disease using same. The above-mentioned object has been accomplished by providing a gene transfer carrier formed from an anaerobic bacterium that can grow specifically at the site of an ischemic disease and can express at least one type of protein that is useful for the diagnosis or treatment of an ischemic disease, a pharmaceutical composition containing the gene transfer carrier, and a treatment method for an ischemic disease utilizing same.
    Type: Application
    Filed: April 20, 2015
    Publication date: October 15, 2015
    Applicant: Anaeropharma Science, Inc.
    Inventors: Yuko Wada, Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki, Hiromi Yonekura
  • Patent number: 8535939
    Abstract: The present invention relates to a secretory signal, a plasmid containing the secretory signal, a transformed anaerobic bacterium transformed with said plasmid, a gene transfer carrier consisting of said anaerobic bacterium, and a pharmaceutical composition containing said carrier.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: September 17, 2013
    Assignee: Anaeropharma Science, Inc.
    Inventors: Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki
  • Publication number: 20130095072
    Abstract: [Object] To provide a gene transfer carrier that specifically accumulates only at a disease site even with systemic administration, has a high protein expression rate, and disappears from the disease site accompanying a cure, and a method for the treatment of an ischemic disease using same. [Solution means] The above-mentioned object has been accomplished by providing a gene transfer carrier formed from an anaerobic bacterium that can grow specifically at the site of an ischemic disease and can express at least one type of protein that is useful for the diagnosis or treatment of an ischemic disease, a pharmaceutical composition containing the gene transfer carrier, and a treatment method for an ischemic disease utilizing same.
    Type: Application
    Filed: July 13, 2012
    Publication date: April 18, 2013
    Applicant: Anaeropharma Science, Inc.
    Inventors: Yuko Wada, Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki
  • Publication number: 20110189758
    Abstract: The present invention relates to a novel secretory signal, a novel plasmid containing the secretory signal, a transformed anaerobic bacterium transformed with said plasmid, a gene transfer carrier consisting of said anaerobic bacterium, and a pharmaceutical composition containing said carrier.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 4, 2011
    Applicant: Anaeropharma Science, Inc.
    Inventors: Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki
  • Publication number: 20110189757
    Abstract: The present invention relates to a novel secretory signal, a novel plasmid containing the secretory signal, a transformed anaerobic bacterium transformed with said plasmid, a gene transfer carrier consisting of said anaerobic bacterium, and a pharmaceutical composition containing said carrier.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 4, 2011
    Applicant: Anaeropharma Science, Inc.
    Inventors: Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki
  • Publication number: 20110190472
    Abstract: The present invention relates to a novel secretory signal, a novel plasmid containing the secretory signal, a transformed anaerobic bacterium transformed with said plasmid, a gene transfer carrier consisting of said anaerobic bacterium, and a pharmaceutical composition containing said carrier.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 4, 2011
    Applicant: Anaeropharma Science, Inc.
    Inventors: Yuko Shimatani-Shibata, Hitomi Shimizu-Matsuhashi, Takayuki Sasaki