Patents by Inventor Ho Kyung Ko

Ho Kyung Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein nanoparticle linked with cancer specific epitope and composition for cancer immunotherapy comprising the same
    Patent number: 10206987
    Abstract: The present invention relates to a protein nanoparticle having a surface on which a cancer-specific epitope is fused and expressed, a method for producing the same, and a composition for cancer immunotherapy containing the protein nanoparticle as an active ingredient, and more specifically, to a recombinant microorganism into which a vector in which a promoter, a gene of a human ferritin heavy chain protein, and a gene encoding the cancer-specific epitope are operably linked is introduced, a protein nanoparticle in which a cancer-specific epitope is fused and expressed on a surface of the human ferritin heavy chain protein, a method of producing the protein nanoparticle, and a composition for cancer immunotherapy including the protein nanoparticle as the active ingredient, wherein the cancer-specific epitope on the surface of the protein nanoparticle according to the present invention is able to be expressed with correct orientation and high density, and the composition for cancer immunotherapy including the
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: February 19, 2019
    Assignees: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jeewon Lee, Bo Ram Lee, Kwangmeyung Kim, Ju Hee Ryu, Ho Kyung Ko
  • PROTEIN NANOPARTICLE LINKED WITH CANCER SPECIFIC EPITOPE AND COMPOSITION FOR CANCER IMMUNOTHERAPY COMPRISING THE SAME
    Publication number: 20170112910
    Abstract: The present invention relates to a protein nanoparticle having a surface on which a cancer-specific epitope is fused and expressed, a method for producing the same, and a composition for cancer immunotherapy containing the protein nanoparticle as an active ingredient, and more specifically, to a recombinant microorganism into which a vector in which a promoter, a gene of a human ferritin heavy chain protein, and a gene encoding the cancer-specific epitope are operably linked is introduced, a protein nanoparticle in which a cancer-specific epitope is fused and expressed on a surface of the human ferritin heavy chain protein, a method of producing the protein nanoparticle, and a composition for cancer immunotherapy including the protein nanoparticle as the active ingredient, wherein the cancer-specific epitope on the surface of the protein nanoparticle according to the present invention is able to be expressed with correct orientation and high density, and the composition for cancer immunotherapy including the
    Type: Application
    Filed: October 21, 2016
    Publication date: April 27, 2017
    Inventors: Jeewon Lee, Bo Ram Lee, Kwangmeyung Kim, Ju Hee Ryu, Ho Kyung Ko