Patents by Inventor Ho Lam Hogan Tang

Ho Lam Hogan Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANASTASIS BIOSENSOR CASPASE TRACKER
    Publication number: 20240182986
    Abstract: The present invention relates to the field of anastasis, i.e., the process of reversal of apoptosis. More specifically, the present invention provides methods and compositions useful for studying anastasis. In one embodiment, a tracking construct of the present invention comprises Lyn11-NES-ERT2-DEVD-rtTA-3×FLAG-DEVD-ERT2-NES. In another embodiment, a construct comprises Lyn11-NES-DEVD-rtTA-3×FLAG. In a further embodiment, a construct comprises ERT2-DEVD-rtTA-3×FLAG-DEVD-ERT2.
    Type: Application
    Filed: May 4, 2023
    Publication date: June 6, 2024
    Inventors: Ho Lam Hogan Tang, Ho Man Holly Tang
  • Anastasis biosensor caspase tracker
    Patent number: 11649509
    Abstract: The present invention relates to the field of anastasis, i.e., the process of reversal of apoptosis. More specifically, the present invention provides methods and compositions useful for studying anastasis. In one embodiment, a tracking construct of the present invention comprises Lyn11-NES-ERT2-DEVD-rtTA-3xFLAG-DEVD-ERT2-NES. In another embodiment, a construct comprises Lyn11-NES-DEVD-rtTA-3xFLAG. In a further embodiment, a construct comprises ERT2-DEVD-rtTA-3XFLAG-DEVD-ERT2.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: May 16, 2023
    Assignee: The Johns Hopkins University
    Inventors: Ho Lam Hogan Tang, Ho Man Holly Tang
  • ANASTASIS BIOSENSOR CASPASE TRACKER
    Publication number: 20200283857
    Abstract: The present invention relates to the field of anastasis, i.e., the process of reversal of apoptosis. More specifically, the present invention provides methods and compositions useful for studying anastasis. In one embodiment, a tracking construct of the present invention comprises Lyn11-NES-ERT2-DEVD-rtTA-3xFLAG-DEVD-ERT2-NES. In another embodiment, a construct comprises Lyn11-NES-DEVD-rtTA-3xFLAG.
    Type: Application
    Filed: November 16, 2018
    Publication date: September 10, 2020
    Inventors: Ho Lam Hogan Tang, Ho Man Holly Tang