Abstract: This disclosure relates to an engineered a novel synthetic artificial stem cell (SASC) system which mimics the paracrine effect of the stem cell secretome and provides tailorability of the composition for targeted tissue regeneration. This novel SASC system demonstrates the feasibility of developing a completely synthetic, tailorable stem cell secretome which reinforces the possibility of developing a new therapeutic strategy that provides better control over targeted tissue engineering applications. Disclosed herein are biodegradable polymeric microspheres that have been used to encapsulate secretome active agents. These microspheres mimic or have the potential to result in a greater therapeutic paracrine effect compared to stem cells, without the added risk of immunological response or the extra pro-inflammatory, antagonistic or inert factors/cytokines. The compositions may be personalized to any disease and/or individual, therefore, adding a much needed element to therapeutics.

Abstract: An air purifying module for use in air channel of an air handling unit of a central air conditioning system, comprising a first housing having air inlet surface and air exhaust surface to enable airflow, a panel member that is detachably installed in the first housing, the panel member comprises filter panel, two metal foam panels and a number of photocatalyst coated metal foam panels arranged in parallel in the direction from the air inlet surface to the air exhaust surface, a shortwave UV light member installed in the first housing, a control unit and a high voltage direct current generator installed in the external of the first housing. The air purifying module can effectively inactivate bacteria and pathogens, filter out volatile organic compounds, thereby providing highly efficient air purification and sterilization functions.