Patents by Inventor Ho Sik Rho

Ho Sik Rho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10570087
    Abstract: The present invention relates to a pseudo-ceramide compound and a preparation method therefor. According to the present invention, the pseudo-ceramide compound has a molecular structure and a function similar to those of a natural ceramide, can be readily synthesized, and has excellent solubility in an organic solvent and excellent stability, and thus the pseudo-ceramide compound can be used as an alternative to a natural ceramide. Therefore, the pseudo-ceramide compound of the present invention can be widely applied to a skin preparation for external use, a cosmetic composition, and the like for reinforcing and maintaining a skin barrier function.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: February 25, 2020
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Yung Hyup Joo, Jae Won Yoo, Yong Jin Kim, Ho Sik Rho, John Hwan Lee
  • Patent number: 10385011
    Abstract: Disclosed are a novel benzoic acid amide derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, or a solvate thereof. The novel compound and the like inhibit melanin production, prevent tyrosinase activity, and have an excellent skin whitening effect.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: August 20, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Yung Hyup Joo, Soo Jeong Choi, Heung Soo Baek, Chang Seok Lee, Jeong Hwan Kim, Yongjin Kim, Hong-Ju Shin, Ho Sik Rho, Song Seok Shin, Jon Hwan Lee
  • Publication number: 20190248736
    Abstract: The present invention relates to a pseudo-ceramide compound and a preparation method therefor. According to the present invention, the pseudo-ceramide compound has a molecular structure and a function similar to those of a natural ceramide, can be readily synthesized, and has excellent solubility in an organic solvent and excellent stability, and thus the pseudo-ceramide compound can be used as an alternative to a natural ceramide. Therefore, the pseudo-ceramide compound of the present invention can be widely applied to a skin preparation for external use, a cosmetic composition, and the like for reinforcing and maintaining a skin barrier function.
    Type: Application
    Filed: September 14, 2017
    Publication date: August 15, 2019
    Applicant: AMOREPACIFIC CORPORATION
    Inventors: Yung Hyup JOO, Jae Won YOO, Yong Jin KIM, Ho Sik RHO, John Hwan LEE
  • Patent number: 10259799
    Abstract: The present invention relates to a novel hydroxyl pyranone compound, a method for producing same, and a cosmetic composition having the compound. The hydroxyl pyranone compound according to the present invention exhibits markedly improved effectiveness compared to the conventional adipocyte differentiation-promoting material, and thus is preferably included as an active ingredient in a cosmetic composition for increasing skin volume or elasticity.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: April 16, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Ho Sik Rho, Jae Won Yoo, Yong Jin Kim
  • Patent number: 10251862
    Abstract: The present invention relates to a cosmetic composition containing a hydroxypyranone derivative compound as an active ingredient for promoting the differentiation of adipocytes. The composition according to the present invention has an effect of promoting the differentiation of adipocytes, and thus allows the differentiation of adipocyte in a skin layer, thereby increasing the skin volume or elasticity. Therefore, the composition of the present invention can be variously used as a cosmetic composition or a pharmaceutical composition in the field, such as skin damage.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: April 9, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Ho Sik Rho, Heung Soo Baek, Yu Jung Kim, Song Seok Shin, John Hwan Lee
  • Patent number: 10238624
    Abstract: Disclosed is a composition for activating longevity genes, particularly, a Sirt-1, Klotho, XPD, ERCC8 or FoxO3a gene, containing a kojic acid derivative as an active ingredient. The composition activates longevity genes, thereby having anticancer, lifetime extension, skin moisturization or skin barrier strengthening effects.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: March 26, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Hyun Jung Kim, Ji Hyun Kim, Jue Won Kim, Ho Sik Rho, Hyun Seo Kang
  • Patent number: 10208009
    Abstract: The present invention relates to a novel hydroxyl pyranone compound, a method for producing same, and a cosmetic composition having the compound. The hydroxyl pyranone compound according to the present invention exhibits markedly improved effectiveness compared to the conventional adipocyte differentiation-promoting material, and thus is preferably included as an active ingredient in a cosmetic composition for increasing skin volume or elasticity.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: February 19, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Ho Sik Rho, Jae Won Yoo, Yong Jin Kim
  • Patent number: 10183926
    Abstract: The present invention relates to a pseudo-ceramide compound and a method for preparing the same. The pseudo-ceramide compound of the present invention may provide antioxidant effects, and exhibits improved properties such as high solubility compared to existing natural ceramides and pseudo-ceramide compounds, and therefore, may be included in large quantities in the formulation. Accordingly, the pseudo-ceramide compound may be used in various fields such as cosmetics, medicinal substances, external preparations and foods.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: January 22, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Yung Hyup Joo, Jae Won Yoo, Yong Jin Kim, Ho Sik Rho, John Hwan Lee
  • Publication number: 20190010137
    Abstract: The present invention relates to a pseudo-ceramide compound and a method for preparing the same. The pseudo-ceramide compound of the present invention may provide antioxidant effects, and exhibits improved properties such as high solubility compared to existing natural ceramides and pseudo-ceramide compounds, and therefore, may be included in large quantities in the formulation. Accordingly, the pseudo-ceramide compound may be used in various fields such as cosmetics, medicinal substances, external preparations and foods.
    Type: Application
    Filed: December 15, 2016
    Publication date: January 10, 2019
    Applicant: AMOREPACIFIC CORPORATION
    Inventors: Yung Hyup JOO, Jae Won YOO, Yong Jin KIM, Ho Sik RHO, John Hwan LEE
  • Publication number: 20180370940
    Abstract: The present invention relates to a novel salicylic acid derivative, a method for preparing the same, and a cosmetic composition for whitening having the same. The compound exhibits a skin whitening effect by acting on tyrosinase, which is a melanin producing enzyme, to inhibit the production of melanin, and exhibits an improved skin whitening effect compared with kojic acid, alkyl salicylic acid, or alkoxy salicylic acid, which is previously known as a skin whitening agent. Therefore, the compound can be variously applied to cosmetics, preparations for external use, and the like.
    Type: Application
    Filed: December 13, 2016
    Publication date: December 27, 2018
    Applicant: AMOREPACIFIC CORPORATION
    Inventors: Ho Sik RHO, Jae Won YOO, Yong Jin KIM
  • Publication number: 20180370939
    Abstract: The present invention relates to a novel hydroxyl pyranone compound, a method for producing same, and a cosmetic composition having the compound. The hydroxyl pyranone compound according to the present invention exhibits markedly improved effectiveness compared to the conventional adipocyte differentiation-promoting material, and thus is preferably included as an active ingredient in a cosmetic composition for increasing skin volume or elasticity.
    Type: Application
    Filed: November 28, 2016
    Publication date: December 27, 2018
    Applicant: AMOREPACIFIC CORPORATION
    Inventors: Ho Sik RHO, Jae Won YOO, Yong Jin KIM
  • Publication number: 20180354925
    Abstract: The present invention relates to a novel hydroxyl pyranone compound, a method for producing same, and a cosmetic composition having the compound. The hydroxyl pyranone compound according to the present invention exhibits markedly improved effectiveness compared to the conventional adipocyte differentiation-promoting material, and thus is preferably included as an active ingredient in a cosmetic composition for increasing skin volume or elasticity.
    Type: Application
    Filed: November 30, 2016
    Publication date: December 13, 2018
    Applicant: AMOREPACIFIC CORPORATION
    Inventors: Ho Sik RHO, Jae Won YOO, Yong Jin KIM
  • Publication number: 20180078522
    Abstract: Disclosed is a composition for activating longevity genes, particularly, a Sirt-1, Klotho, XPD, ERCC8 or FoxO3a gene, containing a kojic acid derivative as an active ingredient. The composition activates longevity genes, thereby having anticancer, lifetime extension, skin moisturization or skin barrier strengthening effects.
    Type: Application
    Filed: March 28, 2016
    Publication date: March 22, 2018
    Inventors: Hyun Jung KIM, Ji Hyun KIM, Jue Won KIM, Ho Sik RHO, Hyun Seo KANG
  • Publication number: 20180065922
    Abstract: Disclosed are a novel benzoic acid amide derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, or a solvate thereof. The novel compound and the like inhibit melanin production, prevent tyrosinase activity, and have an excellent skin whitening effect.
    Type: Application
    Filed: March 30, 2016
    Publication date: March 8, 2018
    Inventors: Yung Hyup JOO, Soo Jeong CHOI, Heung Soo BAEK, Chang Seok LEE, Jeong Hwan KIM, Yongjin KIM, Hong-Ju SHIN, Ho Sik RHO, Song Seok SHIN, Jon Hwan LEE
  • Publication number: 20160324824
    Abstract: The present invention relates to a cosmetic composition containing a hydroxypyranone derivative compound as an active ingredient for promoting the differentiation of adipocytes. The composition according to the present invention has an effect of promoting the differentiation of adipocytes, and thus allows the differentiation of adipocyte in a skin layer, thereby increasing the skin volume or elasticity. Therefore, the composition of the present invention can be variously used as a cosmetic composition or a pharmaceutical composition in the field, such as skin damage.
    Type: Application
    Filed: January 20, 2015
    Publication date: November 10, 2016
    Inventors: Ho Sik RHO, Heung Soo BAEK, Yu Jung KIM, Song Seok SHIN, John Hwan LEE
  • Patent number: 9333145
    Abstract: Provided are a method for neck care and a neck care kit comprising the method, the method comprising: the step of applying acupressure to a Cheonchu acupoint and then applying acupressure downward along a back neckline from the Cheonchu acupoint; the step of applying acupressure to a Yepung acupoint and then applying acupressure downward along the sternocleidomastoid muscle from the Yepung acupoint to the upper margin of the collarbone; the step of applying acupressure to the upper margin of the collarbone and the decollete region (the upper part of breast); and the step of applying acupressure to the region connecting the low margin of the lower jaw and the neck. The method for neck care is considered to have effects of relieving skin wrinkles, improving blood circulation, relieving tension and giving a pleasant stimulation, thereby enabling various applications in the fields of skin care, cosmetics and medicine.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: May 10, 2016
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Ga Young Cho, Eun Joo Kim, Ho Sik Rho, Duck Hee Kim, Han Kon Kim
  • Patent number: 9254251
    Abstract: The present invention relates to a novel benzoic acid amide derivative compound, isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof, or solvates thereof. The novel compound has excellent skin whitening effects.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: February 9, 2016
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Yung Hyup Joo, Heung Soo Baek, Chang Seok Lee, Soo Jeong Choi, Ho Sik Rho, Mi Young Park, Song Seok Shin, Kyung Min Lim, Young Ho Park
  • Patent number: 9028885
    Abstract: Disclosed is a composition comprising an extract of at least one selected from a group consisting of Rehmannia glutinosa, licorice, Coicis Semen, Hordei Fructus, Chaenomelis Fructus, Acanthopanacis Cortex and Puerariae Radix as an active ingredient. The composition promotes adipocyte differentiation and lipid droplet formation and is effective in improving skin wrinkles, enhancing skin elasticity and preventing skin aging.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: May 12, 2015
    Assignee: Amorepacific Corporation
    Inventors: Ji Seong Kim, Ga Young Cho, Eun Joo Kim, Jun Seong Park, Ho Sik Rho, Hye Yoon Park, Duck Hee Kim, Han Kon Kim
  • Patent number: 8906433
    Abstract: The present invention relates to a skin moisturizing cosmetic composition that includes a pine resin extract, a Pinus Densiflora needle extract, and a Pinus Densiflora root extract, as active ingredients. More specifically, the present invention includes a pine resin extract, a Pinus Densiflora needle extract, and a Pinus Densiflora root extract, as active ingredients, and has advantageous effects of improving moisturizing activity on the skin and enhancing skin texture, skin clearness and skin contour.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: December 9, 2014
    Assignee: Amorepacific Corporation
    Inventors: Jeong Cheol Ha, Lee Kyoung Kwon, Youn Joon Kim, Ho Sik Rho, Sang Hoon Han
  • Patent number: 8828456
    Abstract: The present invention relates to a composition for skin external application containing a pine root extract. More specifically, the composition for skin external application according to the present invention contains, as an active ingredient, a pine root extract which shows various effects, including eliminating free radicals, protecting the cell membrane from damage by UV radiation, inhibiting the production of reactive oxygen species caused by UV radiation, inhibiting the reduction in the expression of superoxide dismutase (SOD) and catalase caused by UV radiation, stimulating the production of HSP70 to protect cells, inhibiting MMP-2 biosynthesis caused by UV radiation, inducing the expression of SIRT1 gene that restores DNA damage, and inducing the expression of LMNA1 gene that maintains the structure of the nuclear membrane. Ultimately, the composition of the present invention prevents skin aging.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: September 9, 2014
    Assignee: Amorepacific Corporation
    Inventors: Ho Sik Rho, Eun Joo Kim, Ga Young Cho, Hye Yoon Park, Ji Seong Kim, Duck Hee Kim, Han Kon Kim