Patents by Inventor HoTae Lim

HoTae Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPTICALLY CONTROLLABLE FGFR STIMULATION USING WIRELESS CONTROLLED CELLULAR LIGHTING SYSTEM
    Publication number: 20230105479
    Abstract: The present invention relates to the field of stem cells. More specifically, the present invention provides compositions and methods for using optogenetics to sustain the pluripotency of stem cells. In one embodiment, a vector comprises a nucleotide sequencing encoding a fusion protein comprising the intracellular domain of fibroblast growth factor 1 receptor (FGFR1) and a photoactivatable domain.
    Type: Application
    Filed: September 30, 2022
    Publication date: April 6, 2023
    Applicant: The Johns Hopkins University
    Inventors: Gabsang Lee, Hyesoo Kim, InYoung Choi, HoTae Lim, Alex V. Huynh
  • ISOLATION OF FUSION-COMPETENT MYOBLASTS AND THERAPEUTIC APPLICATIONS THEREOF RELATED TO MUSCULAR DYSTROPHY
    Publication number: 20220401493
    Abstract: Described are methods of isolating high purity myoblasts that are used to create novel DMD model systems and methods using human induced pluripotent stem cells (hiPSCs). Also described are therapeutic methods based on the use of there myoblasts.
    Type: Application
    Filed: February 4, 2022
    Publication date: December 22, 2022
    Inventors: Gabsang Lee, InYoung Choi, HoTae Lim, Kathryn R. Wagner
  • Isolation of fusion-competent myoblasts and therapeutic applications thereof related to muscular dystrophy
    Patent number: 11318167
    Abstract: Described are methods of isolating high purity myoblasts that are used to create novel DMD model systems and methods using human induced pluripotent stem cells (hiPSCs). Also described are therapeutic methods based on the use of these myoblasts.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: May 3, 2022
    Assignee: The Johns Hopkins University
    Inventors: Gabsang Lee, InYoung Choi, HoTae Lim, Kathryn R. Wagner
  • OPTICALLY CONTROLLABLE FGFR STIMULATION USING WIRELESS CONTROLLED CELLULAR LIGHTING SYSTEM
    Publication number: 20210221858
    Abstract: The present invention relates to the field of stem cells. More specifically, the present invention provides compositions and methods for using optogenetics to sustain the pluripotency of stem cells. In one embodiment, a vector comprises a nucleotide sequencing encoding a fusion protein comprising the intracellular domain of fibroblast growth factor 1 receptor (FGFR1) and a photoactivatable domain.
    Type: Application
    Filed: January 19, 2021
    Publication date: July 22, 2021
    Inventors: Gabsang Lee, Hyesoo Kim, InYoung Choi, HoTae Lim, Alex V. Huynh
  • ISOLATION OF FUSION-COMPETENT MYOBLASTS AND THERAPEUTIC APPLICATIONS THEREOF RELATED TO MUSCULAR DYSTROPHY
    Publication number: 20180360887
    Abstract: Described are methods of isolating high purity myoblasts that are used to create novel DMD model systems and methods using human induced pluripotent stem cells (hiPSCs). Also described are therapeutic methods based on the use of these myoblasts.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 20, 2018
    Inventors: Gabsang Lee, InYoung Choi, HoTae Lim, Kathryn R. Wagner