Abstract: The present invention relates to a novel method for producing an intermediate expressed by chemical formula 5 that can be effectively used in synthesis of sphingosine-1-phosphate receptor agonist.

Abstract: The present invention relates to a crystalline form II represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form II represented by formula 1 of the present invention may be characterized by XRD patterns, DSC profiles, and/or TGA profiles.

Abstract: The present invention relates to a crystalline form III represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form III represented by formula 1 of the present invention may be characterized by XRD patterns, DSC profiles, and/or TGA profiles.

Abstract: The present invention relates to a crystalline form I represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form I represented by formula 1 of the present invention may be characterized by XRD patterns, DSC profiles, and/or TGA profiles.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present disclosure can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: The present invention relates to a 6-6 bicyclic ring-containing compound derivative and use thereof. The compound according to the present invention acts as a PRMT5 inhibitor, and thus can be effectively used in the prevention or treatment of diseases caused by PRMT5.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: A method of a roaming user equipment (UE) according to an embodiment of the disclosure includes obtaining billing information of the roaming UE from a message received from a communication carrier server, sending a billing information authentication request message including the obtained billing information to an authentication server, and receiving an authentication result regarding whether the billing information is valid.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: Disclosed is a method by which a first terminal supports vehicle-to-everything (V2X) communication through a first data transmission, comprising the steps of: determining a wireless resource for a second data transmission of a second terminal; transmitting, to the second terminal, first data including information of the wireless resource; and receiving, by using the wireless resource, second data transmitted from the second terminal.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: The present disclosure relates to an apparatus and a method for managing a Mission Critical Push-to-Talk (MCPTT). The apparatus comprises: a first MCPTT client configured to send an MCPTT request message to a second MCPTT client through a MCPTT server, and receive, from the second MCPTT client through the MCPTT server, a MCPTT response message in response to the MCPTT request message, wherein an MCPTT call in the MCPTT service is established between the first MCPTT client and the second MCPTT client by the MCPTT server.

Abstract: Disclosed is a method by which a first terminal supports vehicle-to-everything (V2X) communication through a first data transmission, comprising the steps of: determining a wireless resource for a second data transmission of a second terminal; transmitting, to the second terminal, first data including information of the wireless resource; and receiving, by using the wireless resource, second data transmitted from the second terminal.

Abstract: A method for establishing a plurality of protocol data unit (PDU) sessions between a user equipment (UE) and a data network (DN) by the UE may comprise transmitting a message to establish the plurality of PDU sessions to at least one network function (NF) of a plurality of NFs, exchanging a signal to establish the plurality of PDU sessions among the UE, a radio access network (RAN), and the plurality of NFs based on the message, and establishing the plurality of PDU sessions between the UE and the DN according to predetermined priority and based on the signal, wherein each of the plurality of PDU sessions corresponds to a network slice (NS) for a particular service, wherein the message includes information about the particular service corresponding to the plurality of PDU sessions, and wherein the priority is determined based on the information about the particular service.

Abstract: The present invention provides facile and accurate molecular diagnosis of disease-specific genes capable of the naked eye detection through amplifying the target genes to selectively block the fluid path in a microfluidic device. Specifically, the present invention includes an isothermal amplification of target genes through a rolling circle amplification, a microfluidic device for detecting pathogen genes, and a detection method using the same. Therefore, the present invention can conveniently detect a single target gene, such as a single pathogen, or at the same time, several target genes, such as several pathogens, without complicated mechanical equipment.

Abstract: A method for providing a multimedia broadcast/multicast service (MBMS) to a terminal related to a vehicle by a broadcast and multicast service center (BM-SC) is provided. The method includes identifying at least one candidate service area that the terminal is predicted to pass through, and transmitting, to an MBMS-gateway (MBMS-GW), a request for configuring the radio bearer of the at least one candidate service area.

Abstract: Provided are a method and apparatus for interpolating X-ray tomographic image data by using a machine learning model. A method of interpolating an X-ray tomographic image or X-ray tomographic composite image data includes obtaining a trained model parameter via machine learning that uses a sub-sampled sinogram for learning as an input and uses a full-sampled sinogram for learning as a ground truth; radiating X-rays onto an object at a plurality of preset angular locations via an X-ray source, and obtaining a sparsely-sampled sinogram including X-ray projection data obtained via X-rays detected at the plurality of preset angular locations; applying the trained model parameter to the sparsely-sampled sinogram by using the machine learning model; and generating a densely-sampled sinogram by estimating X-ray projection data not obtained with respect to the object on the sparsely-sampled sinogram.

Abstract: Embodiments herein provide a method for identity management across multiple planes. The method includes receiving, by a MCPTT server, a first request message to establish a call between a first MCPTT client and the one or more second MCPTT client from a signaling plane entity. The first request message includes an application plane identity of the one or more second MCPTT client. Further, the method includes translating, at the MCPTT server, the application plane identity of the one or more second MCPTT client to a signaling plane identity of the one or more second MCPTT client. Furthermore, the method includes sending, by the MCPTT server, the one or more second request message including the signaling plane identity of the one or more second MCPTT client to the second MCPTT client for establishing the call via the signaling plane entity.

Abstract: Disclosed is a fifth generation (5G) or pre-5G communication system for supporting higher data transmission rates beyond fourth generation (4G) communication systems such as LTE systems. A data communication method includes receiving information about a reception rate of a signal from a second user equipment (UE) performing device-to-device (D2D) communication with a first UE, receiving location information about at least one of the first UE and the second UE, determining a data communication configuration for the D2D communication based on the reception rate information and the location information, and transmitting the determined data communication configuration to at least one of the first UE and the second UE.