Patents by Inventor Ho Yin Lo

Ho Yin Lo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinazolinedione chymase inhibitors
    Patent number: 8377949
    Abstract: Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving Chymase.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: February 19, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Xin Guo, Ho Yin Lo, Chuk Chui Man, Hidenori Takahashi
  • BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20120277227
    Abstract: The present invention relates to compounds of formula (IA), (IB) and (IC): and pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: October 26, 2011
    Publication date: November 1, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Stephane DE LOMBAERT, Weimin LIU, Ho Yin LO, Peter Allen NEMOTO
  • BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20120277226
    Abstract: The present invention relates to compounds of formula (IA) and (IB): and pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: October 26, 2011
    Publication date: November 1, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Zhidong CHEN, Stephane DE LOMBAERT, Jonathon Alan DINES, Weimin LIU, Ho Yin LO, Pui Leng LOKE
  • OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20120245162
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein.
    Type: Application
    Filed: September 20, 2011
    Publication date: September 27, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, John D. HUBER, Weimin LIU, Ho Yin LO, Pui Leng LOKE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
  • OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20120220561
    Abstract: The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: August 12, 2011
    Publication date: August 30, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, John D. HUBER, Ho Yin LO, Pui Leng LOKE, Weimin LIU, Tina Marie MORWICK, Alan OLAGUE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
  • OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20120214787
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: August 23, 2011
    Publication date: August 23, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, Jonathon Alan DINES, John D. HUBER, Weimin LIU, Ho Yin LO, Pui Leng LOKE, Tina Marie MORWICK, Peter Allen NEMOTO, Alan OLAGUE, Doris RIETHER, Heather Tye, Lifen WU, Renee M. ZINDELL
  • Quinazolinedione Chymase Inhibitors
    Publication number: 20120122863
    Abstract: Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving Chymase.
    Type: Application
    Filed: August 12, 2008
    Publication date: May 17, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Xin Guo, Ho Yin Lo, Chuk Chui Man, Hidenori Takahashi
  • BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20110301161
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salt thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: December 1, 2010
    Publication date: December 8, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Zhidong CHEN, Ming-Hong HAO, Weimin LIU, Ho-Yin LO, Pui Leng LOKE, Chuk Chui MAN, Tina Marie MORWICK, Peter Allen NEMOTO, Hidenori TAKAHASHI, Heather TYE, Lifen WU
  • INDOLIZINE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20110275627
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salt thereof, wherein X1 to X4, R1 to R4, A, B, D and m are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: August 25, 2009
    Publication date: November 10, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Todd Bosanac, Stephane De Lombaert, Ho Yin Lo, Peter Allen Nemoto, Alan Olague
  • AZA-BENZIMIDAZOLONE CHYMASE INHIBITORS
    Publication number: 20110269780
    Abstract: Disclosed are small molecule inhibitors of the formula (I): and the pharmaceutical compositions thereof and processes of making the same. The compounds are useful in treating various diseases and conditions involving chymase.
    Type: Application
    Filed: August 25, 2009
    Publication date: November 3, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Michel Jose Emmanuel, Xin Guo, Jin Mi Kim, Ho Yin Lo, Peter Allen Nemoto, Kevin Chungeng Qian
  • Benzimidazolone Chymase Inhibitors
    Publication number: 20100240702
    Abstract: Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.
    Type: Application
    Filed: May 15, 2008
    Publication date: September 23, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Asitha Abeywardane, Brian Nicholas Cook, Stephane De Lombaert, Michel Jose Emmanuel, Xin Guo, Ming-Hong Hao, Jin Mi Kim, Ho Yin Lo, Chuk Chui Man, Tina Marie Morwick, Peter Allen Nemoto, Kevin Chungeng Qian, Hidenori Takahashi, Steven John Taylor
  • Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors
    Publication number: 20090227588
    Abstract: Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.
    Type: Application
    Filed: November 14, 2006
    Publication date: September 10, 2009
    Inventors: Roman Wolfgang Fleck, Xin Guo, Ho Yin Lo, Chuk Chui Man
  • Substituted benzimidazole compounds
    Patent number: 7138420
    Abstract: Disclosed are substituted benzimidazole compounds of formula (I): wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: November 21, 2006
    Assignee: Boehringer Ingelheim Pharmaceuticals Inc.
    Inventors: Joerg Martin Bentzien, Brian Nicholas Cook, Charles Cywin, Roman Wolfgang Fleck, Ho Yin Lo, Peter Allen Nemoto, Steven S. Pullen, Gregory Paul Roth, Roger John Snow, Hidenori Takahashi, Ji Wang, Kevin J. Moriarty, Lei Qiao, Michael Winters