Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: Disclosed is an interface circuit including a first parallel-to-serial conversion circuit suitable for converting inverted parallel data in a parallel-to-serial manner to generate first output data in a test mode; a second parallel-to-serial conversion circuit suitable for converting non-inverted parallel data in the parallel-to-serial manner to generate second output data in the test mode; a third parallel-to-serial conversion circuit suitable for converting the non-inverted parallel data in the parallel-to-serial manner to generate third output data in the test mode; a fourth parallel-to-serial conversion circuit suitable for converting the inverted parallel data in the parallel-to-serial manner to generate fourth output data in the test mode; a first driver circuit suitable for receiving the first and second output data in the test mode; and a second driver circuit suitable for receiving the third and fourth output data in the test mode.

Abstract: The present invention relates to a modified conjugated diene-based polymer having excellent rolling resistance and improved processability, a method for preparing the same and a rubber composition including the same, and provides a modified conjugated diene-based polymer which includes a repeating unit derived from a conjugated diene-based monomer, and a functional group derived from a modifier, and satisfies conditions (i) to (vii), a method for preparing the same and a rubber composition including the same.

Abstract: A vehicle seat lumbar support including: brackets located on both sides of a seat back frame; a fixing unit having guides for guiding an operating unit and a driver including a motor having a driving shaft, a worm fitted to the driving shaft of the motor, a worm gear rotating by the worm, and a pinion gear fitted to a shaft of the worm gear; and an operating unit driven by the driver and including a block band having base blocks having hooks formed on underside surfaces thereof, a base band for locking the hooks of the base blocks thereonto in such a manner as to be coupled to the guides on top and underside of one side thereof, and a rack gear formed on the base band in such a manner as to engage with the pinion gear fitted to the shaft of the worm gear.

Abstract: An image forming apparatus supplies a printing medium to a development apparatus upon single-sided printing or double-sided printing. The image forming apparatus may include a printing medium supplying apparatus provided such that various kinds of printing media are compatible. Accordingly, the single-sided printing and the double-sided printing can be easily performed regardless of the size of the printing medium.

Abstract: A paper feeding apparatus includes a pickup roller, a knock-up plate to accommodate recording media thereon and capable of moving to a pickup position and a release position, a forward roller to transfer a recording medium picked up by the pickup roller, a retard roller capable of moving to a contact position and to a separation position, a first control unit to move the knock-up plate to the pickup position and the release position, and a second control unit to move the knock-up plate to the contact position and the separation position, wherein the first control unit and the second control unit are driven by a single driving motor.

Abstract: An apparatus and method for compensating Quality of Service (QoS) during a handover of a Mobile Station (MS) by a serving Base Station (BS) and a target BS in a wireless broadband access system are provided. The method includes generating a message during a handover from the serving BS to a target BS, the message including at least one of a data transmission/reception time just before the handover, a size of a time window for which a data transmission/reception history is recorded in an accumulated way, and an amount of data transmitted/received during the time window, and transmitting the message to the target BS. The target BS can more accurately find a handover break time and the amount of data transmission/reception in the serving BS at the time the MS has been handed over to the target BS, enabling fast and adequate QoS compensation/correction for each QoS class, and thus facilitating flexible, efficient and accurate QoS provisioning regardless of controlled handover and uncontrolled handover.

Abstract: The present invention relates to a composition having an anti-inflammatory activity, comprising extracts or fractions of Chrysanthemum boreale Makino. Since the composition show the prophylactic and therapeutic effects on inflammatory diseases, in particular, atopic dermatitis, it can be used as a pharmaceutical composition, and also applied to various fields, including quasi-drugs, cosmetic compositions, foods, and water softeners.

Abstract: A paper feeding apparatus includes a pickup roller, a knock-up plate to accommodate recording media thereon and capable of moving to a pickup position and a release position, a forward roller to transfer a recording medium picked up by the pickup roller, a retard roller capable of moving to a contact position and to a separation position, a first control unit to move the knock-up plate to the pickup position and the release position, and a second control unit to move the knock-up plate to the contact position and the separation position, wherein the first control unit and the second control unit are driven by a single driving motor.

Abstract: The present invention relates to a composition having an anti-inflammatory activity, comprising extracts or fractions of Chrysanthemum boreale Makino. Since the composition show the prophylactic and therapeutic effects on inflammatory diseases, in particular, atopic dermatitis, it can be used as a pharmaceutical composition, and also applied to various fields, including quasi-drugs, cosmetic compositions, foods, and water softeners.

Abstract: An image forming apparatus and a controlling method thereof. The image forming apparatus includes a fixing member having a heating source to heat a developer of a recording medium, a power supply unit to the heating source, first and second temperature sensors for respective first and second positions on the fixing member, a width sensor for the recording medium, and a control unit, when a difference between the first temperature and the second temperature is greater than a predetermined reference value, determining whether the first temperature is abnormal based on the width of the recording medium and, when the first temperature is abnormal, interrupting the power supply to the heating source. An error in the temperature sensor is determined when a temperature difference between the first and second position of the fixing member is greater than a predetermined degree and the recording medium passes through both temperature sensors.

Abstract: An apparatus and method for compensating Quality of Service (QoS) during a handover of a Mobile Station (MS) by a serving Base Station (BS) and a target BS in a wireless broadband access system are provided. The method includes generating a message during a handover from the serving BS to a target BS, the message including at least one of a data transmission/reception time just before the handover, a size of a time window for which a data transmission/reception history is recorded in an accumulated way, and an amount of data transmitted/received during the time window, and transmitting the message to the target BS. The target BS can more accurately find a handover break time and the amount of data transmission/reception in the serving BS at the time the MS has been handed over to the target BS, enabling fast and adequate QoS compensation/correction for each QoS class, and thus facilitating flexible, efficient and accurate QoS provisioning regardless of controlled handover and uncontrolled handover.

Abstract: An image forming apparatus and a controlling method thereof. The image forming apparatus includes a fixing member having a heating source to heat a developer of a recording medium, a power supply unit to the heating source, first and second temperature sensors for respective first and second positions on the fixing member, a width sensor for the recording medium, and a control unit, when a difference between the first temperature and the second temperature is greater than a predetermined reference value, determining whether the first temperature is abnormal based on the width of the recording medium and, when the first temperature is abnormal, interrupting the power supply to the heating source. An error in the temperature sensor is determined when a temperature difference between the first and second position of the fixing member is greater than a predetermined degree and the recording medium passes through both temperature sensors.

Abstract: Disclosed is a head-up display device for vehicles. The display device for vehicles includes a panel, on which driving data of a vehicle are displayed; and an aspheric combiner, which magnifies the driving data displayed on the panel and thus creates a virtual image, and has a ratio of DISC to CRC satisfying the below expression (here, 0<|DISC/CRC|<1.0, DISC representing the distance on an optical route between the panel and the combiner, and CRC representing the radius of curvature of the combiner).

Abstract: A projection lens system that has a compact configuration and is capable of correcting a color aberration. In the system, first and second lenses have a weak refractive power, respectively, and a third lens has a strong positive refractive power. A fourth lens corrects an aberration generated by the third lens, and a fifth lens has a negative refractive power. A diffractive optical element is formed on at least one among the surface of the first to fifth lenses. A color aberration and spherical aberration is corrected with the diffractive optical element, so that a high resolution can be realized without increasing the number of lenses and the manufacturing cost can be reduced.

Abstract: Disclosed is a head-up display device for vehicles. The display device for vehicles includes a panel, on which driving data of a vehicle are displayed; and an aspheric combiner, which magnifies the driving data displayed on the panel and thus creates a virtual image, and has a ratio of DISC to CRC satisfying the below expression (here, 0<|DISC/CRC|<1.0, DISC representing the distance on an optical route between the panel and the combiner, and CRC representing the radius of curvature of the combiner).

Abstract: A polarization conversion system comprises a glass substrate; reflection type polarization plates, formed between top and bottom surfaces of the glass substrate and inclined at a predetermined angle, separating unpolarized incident light into two polarization directions where two directions are at a right angle to each other; polarization conversion plates coupled to the reflection type polarization plates, converting a polarization direction of polarization light by the reflection type polarization plates; and reflection plates positioned in parallel with the reflection type polarization plates, reflecting incident light from the reflection type polarization plates.

Abstract: A diversity antenna distance determining method in radio telecommunications base station is provided. The method comprising the step of determining an allowable correlation coefficient of signals received through the first and the second antennas in a first frequency band which provides good diversity performance; determining a first distance d1 between the antennas which satisfies the determined correlation coefficient in the first frequency band; and, determining a second distance d2 between the two antennas based on d1 in a second frequency band, which is different from the first frequency band. In the present invention, an optimal distance between antennas at one frequency is calculated using the data measured at another frequency to compensate the fading within a coverage area.