Patents by Inventor Hoang V. Le

Hoang V. Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10800753
    Abstract: Tetrahydrothiophene and related heterocyclic analogs and related methods for GABA aminotransferase inactivation.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: October 13, 2020
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Dustin D. Hawker
  • Publication number: 20200281880
    Abstract: Disclosed are methods, compounds, and compositions for treating infection by an Apicomplexan parasite that include administering a compound that selectively inactivates ornithine aminotransferase of the Apicomplexan parasite. Specifically, the methods, compounds, compounds may be utilized for treating infection by Toxoplasma gondii and toxoplasmosis and for treating infection by Plasmodium falciparum and malaria. The compounds disclosed herein are observed to selectively inactivate Toxoplasma gondii ornithine aminotransferase (TgOAT) relative to human OAT and relative to human ?-aminobutyric aminotransferase (GABA-AT).
    Type: Application
    Filed: March 31, 2020
    Publication date: September 10, 2020
    Applicant: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Rima L. McLeod, Dustin D. Hawker
  • Patent number: 10632088
    Abstract: Disclosed are methods, compounds, and compositions for treating infection by an Apicomplexan parasite that include administering a compound that selectively inactivates ornithine aminotransferase of the Apicomplexan parasite. Specifically, the methods, compounds, compounds may be utilized for treating infection by Toxoplasma gondii and toxoplasmosis and for treating infection by Plasmodium falciparum and malaria. The compounds disclosed herein are observed to selectively inactivate Toxoplasma gondii ornithine aminotransferase (TgOAT) relative to human OAT and relative to human ?-aminobutyric aminotransferase (GABA-AT).
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: April 28, 2020
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Rima L. McLeod, Dustin D. Hawker
  • Publication number: 20190338179
    Abstract: Scales are prevented or inhibited from forming in a well or in a formation penetrated by a well by pumping into the well a fluid comprising a hydratable polymer, a crosslinking agent, such as an organometallic crosslinking agent containing a polyvalent metal and a scale inhibitor selected from the group consisting of polyvinyl sulfonates, a polyacrylamidomethylpropane sulfonic acid, carboxymethyl inulin and sulfonated polyacrylates and mixtures thereof.
    Type: Application
    Filed: July 18, 2019
    Publication date: November 7, 2019
    Inventors: Dong Shen, Dora V. Galvan, Hoang V. Le, Qi Qu
  • Patent number: 10392553
    Abstract: Scales are prevented or inhibited from forming in a well or in a formation penetrated by a well by pumping into the well a fluid comprising a hydratable polymer, a crosslinking agent, such as an organometallic crosslinking agent containing a polyvalent metal and a scale inhibitor selected from the group consisting of polyvinyl sulfonates, a polyacrylamidomethylpropane sulfonic acid, carboxymethyl inulin and sulfonated polyacrylates and mixtures thereof.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: August 27, 2019
    Assignee: BAKER HUGHES, A GE COMPANY, LLC
    Inventors: Dong Shen, Dora V. Galvan, Hoang V. Le, Qi Qu
  • Publication number: 20190256489
    Abstract: Tetrahydrothiophene and related heterocyclic analogs and related methods for GABA aminotransferase inactivation.
    Type: Application
    Filed: January 18, 2019
    Publication date: August 22, 2019
    Applicant: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Dustin D. Hawker
  • Publication number: 20190251449
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for structuring and training a recurrent neural network. This describes a technique that improves the ability to capture long term dependencies in recurrent neural networks by adding an unsupervised auxiliary loss at one or more anchor points to the original objective. This auxiliary loss forces the network to either reconstruct previous events or predict next events in a sequence, making truncated backpropagation feasible for long sequences and also improving full backpropagation through time.
    Type: Application
    Filed: February 11, 2019
    Publication date: August 15, 2019
    Inventors: Andrew M. Dai, Quoc V. Le, Hoang Trieu Trinh, Thang Minh Luong
  • Patent number: 10189807
    Abstract: Tetrahydrothiophene and related heterocyclic analogs and related methods for GABA aminotransferase inactivation.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: January 29, 2019
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Dustin D. Hawker
  • Publication number: 20180271816
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Application
    Filed: May 29, 2018
    Publication date: September 27, 2018
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Patent number: 9993449
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: June 12, 2018
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Publication number: 20180098952
    Abstract: Disclosed are methods, compounds, and compositions for treating infection by an Apicomplexan parasite that include administering a compound that selectively inactivates ornithine aminotransferase of the Apicomplexan parasite. Specifically, the methods, compounds, compounds may be utilized for treating infection by Toxoplasma gondii and toxoplasmosis and for treating infection by Plasmodium falciparum and malaria. The compounds disclosed herein are observed to selectively inactivate Toxoplasma gondii ornithine aminotransferase (TgOAT) relative to human OAT and relative to human ?-aminobutyric aminotransferase (GABA-AT).
    Type: Application
    Filed: October 10, 2017
    Publication date: April 12, 2018
    Applicant: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Rima L. McLeod, Dustin D. Hawker
  • Publication number: 20180051001
    Abstract: Tetrahydrothiophene and related heterocyclic analogs and related methods for GABA aminotransferase inactivation.
    Type: Application
    Filed: September 22, 2017
    Publication date: February 22, 2018
    Applicant: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Dustin D. Hawker
  • Patent number: 9856231
    Abstract: Tetrahydrothiophene and related heterocyclic analogs and related methods for GABA aminotransferase inactivation.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: January 2, 2018
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Hoang V. Le, Dustin D. Hawker
  • Publication number: 20170239202
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Application
    Filed: May 4, 2017
    Publication date: August 24, 2017
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Patent number: 9670141
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: June 6, 2017
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Publication number: 20170101364
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Application
    Filed: October 10, 2016
    Publication date: April 13, 2017
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Publication number: 20160264544
    Abstract: Tetrahydrothiophene and related heterocyclic analogs and related methods for GABA aminotransferase inactivation.
    Type: Application
    Filed: March 9, 2016
    Publication date: September 15, 2016
    Inventors: Richard B. Silverman, Hoang V. Le, Dustin D. Hawker
  • Publication number: 20150060062
    Abstract: Scales are prevented or inhibited from forming in a well or in a formation penetrated by a well by pumping into the well a fluid comprising a hydratable polymer, a crosslinking agent, such as an organometallic crosslinking agent containing a polyvalent metal and a scale inhibitor selected from the group consisting of polyvinyl sulfonates, a polyacrylamidomethylpropane sulfonic acid, carboxymethyl inulin and sulfonated polyacrylates and mixtures thereof.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 5, 2015
    Inventors: Dong Shen, Dora V. Galvan, Hoang V. Le, Qi Qu
  • Patent number: 6387853
    Abstract: Polymers are derivatized and then may be introduced into a wellbore, such as in a hydraulic fracturing treatment. A polymer may be a guar powder that is mixed with a organic solvent and derivatized using a derivatizing agent, such as sodium chloroacetate. The polymer is typically derivatized in bulk prior to introduction into the wellbore. The derivatized polymer may be hydrated and/or crosslinked prior to introduction into the wellbore.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: May 14, 2002
    Assignee: BJ Services Company
    Inventors: Jeffrey C. Dawson, Subramanian Kesavan, Hoang V. Le
  • Patent number: 6228812
    Abstract: Compositions and methods for modifying the permeability of subterranean formations for the purpose of selectively reducing excessive production of aqueous fluids. The compositions include copolymers which may be added to an aqueous fluid to form a water control treatment fluid. The copolymers may include copolymers having a hydrophillic monomeric unit, a first anchoring monomeric unit and a filler monomeric unit, with the first anchoring monomeric unit being based on N-vinylformamide. Additional anchoring monomeric units may also optionally be present. The copolymers may be employed in well treatment fluids introduced into production wells or injection wells. The copolymers may also be utilized in conjunction with stimulation treatments and with introduction of other well treatment fluids.
    Type: Grant
    Filed: April 5, 1999
    Date of Patent: May 8, 2001
    Assignee: BJ Services Company
    Inventors: Jeffrey C. Dawson, Hoang V. Le, Subramanian Kesavan