Patents by Inventor Hobbe Smit

Hobbe Smit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050038125
    Abstract: The present invention relates to a method for the treatment and/or prevention of disorders with elevated PGE2 and/or LTB4 levels, comprising administering to a mammal an effective amount of pterostilbene component (PS component), a pharmaceutically acceptable salt of PS component or a precursor of PS component, wherein the PS component has the formula in which R1, R2 and R3 are independently selected from hydrogen, C1-50 hydrocarbyl, C1-50 substituted hydrocarbyl, C1-50 heterohydrocarbyl, C1-50 substituted heterohydrocarbyl; and wherein at least one of R1 and R2 is not hydrogen
    Type: Application
    Filed: August 15, 2003
    Publication date: February 17, 2005
    Inventors: Hobbe Smit, Sander Hougee, John Sijben
  • Publication number: 20040192579
    Abstract: The present invention is concerned with the treatment or prevention of cancer, H. pylori infections, chronic inflammatory conditions, cardiovascular diseases or cerebral vascular diseases in a mammal, comprising the administration of the mammal of an effective amount of a composition containing a matrine component and dictamnine. Another aspect of the invention relates to a composition comprising at least 15 &mgr;mole of a matrine component and at least 0.15 &mgr;mole of dictamnine.
    Type: Application
    Filed: February 27, 2004
    Publication date: September 30, 2004
    Inventors: John Wah Tze, Theresa Chiang Tze, Peizhong Lin, Stephen Lam, Joseph Tai, Frisi Hobbe Smit, Adrianus Lambertus Bertholdus Van Helvoort, Robert Johan Joseph Hageman
  • Publication number: 20040170704
    Abstract: The present invention is concerned with a process for the manufacture of a herbal composition, said process comprising: a. subjecting a matrine containing plant material, in the absence of a plant material derived from the species Dictamnus, to an extraction with an aqueous solvent, optionally followed by a concentration step, to produce a herbal extract I; b. subjecting a plant material derived from the species Dictamnus, to an extraction with an aqueous solvent, optionally followed by a concentration step, to produce a herbal extract II; c. mixing the herbal extracts I and II; d. provided the resulting mixture contains a significant amount of water, drying the mixture to a water content of less than 6 wt. %. The herbal composition according to the present invention may advantageously be used in a method of treating or preventing cancer, H. pylori infections, chronic inflammatory conditions, cardiovascular diseases or cerebral vascular diseases in mammals.
    Type: Application
    Filed: February 6, 2004
    Publication date: September 2, 2004
    Inventors: John Wah Tze, Peizhong Lin, Stephen Lam, Joseph Tai, Frisi Hobbe Smit, Adrianus Lambertus Bertholdus Van Helvoort, Robert Johan Joseph Hageman