Patents by Inventor Hock Lai Khoo

Hock Lai Khoo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9855558
    Abstract: An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: January 2, 2018
    Assignee: APPLIED BIOSYSTEM, LLC
    Inventors: Hon Siu Shin, Hock Lai Khoo
  • Patent number: 9457351
    Abstract: The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: October 4, 2016
    Assignee: Applied Biosystems, LLC
    Inventors: Lim Hi Tan, Jew Kwee Ngui, Hon Siu Shin, Ui Leng Soh, Yang Hooi Kee, Hock Lai Khoo, Mark T. Reed, Wolfgang Heimberg
  • Publication number: 20140273182
    Abstract: The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: APPLIED BIOSYSTEMS, LLC
    Inventors: Lim Hi Tan, Jew Kwee Ngui, Hon Siu Shin, Ui Leng Soh, Yang Hooi Kee, Hock Lai Khoo, Mark T. Reed, Wolfgang Heimberg
  • Patent number: 8676383
    Abstract: The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: March 18, 2014
    Assignee: Applied Biosystems, LLC
    Inventors: Lim Hi Tan, Jew Kwee Ngui, Hon Siu Shin, Ui Leng Soh, Yang Hooi Kee, Hock Lai Khoo, Mark T. Reed, Ching Ong Lau, Wolfgang Heimberg
  • Publication number: 20130230915
    Abstract: An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
    Type: Application
    Filed: April 30, 2013
    Publication date: September 5, 2013
    Applicant: APPLIED BIOSYSTEM, LLC
    Inventors: Hon Siu SHIN, Hock Lai KHOO
  • Patent number: 8440454
    Abstract: An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: May 14, 2013
    Assignee: Applied Biosystems, LLC
    Inventors: Hon Siu Shin, Hock Lai Khoo
  • Publication number: 20110200501
    Abstract: An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
    Type: Application
    Filed: April 27, 2011
    Publication date: August 18, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Hon Siu SHIN, Hock Lai Khoo
  • Patent number: 7935524
    Abstract: An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: May 3, 2011
    Assignee: Applied Biosystems, LLC
    Inventors: Hon Siu Shin, Hock Lai Khoo
  • Publication number: 20100129876
    Abstract: An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
    Type: Application
    Filed: January 29, 2010
    Publication date: May 27, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Hon Siu SHIN, Hock Lai KHOO
  • Patent number: 7659109
    Abstract: An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal cycling by a thermoelectric module.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: February 9, 2010
    Assignee: Applied Biosystems, LLC
    Inventors: Hon Siu Shin, Hock Lai Khoo
  • Publication number: 20080274511
    Abstract: The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.
    Type: Application
    Filed: September 5, 2007
    Publication date: November 6, 2008
    Inventors: Lim Hi TAN, Jew Kween Ngui, Hon Siu Shin, Ui Leng Soh, Yang Hooi Kee, Hock Lai Khoo, Mark T. Reed, Ching Ong Lau, Wolfgang Heimberg