Abstract: A system for depositing tags in an array includes a substrate holder, a tag depositor, and a positioner. The substrate holder is configured to hold a substrate. The tag depositor is configured to deposit tags on the substrate. The positioner is configured to position the tag depositor relative to the substrate.

Abstract: A system detects an analyte suspected of being present in a sample. The reader reads an optical tag on a substrate, which is configured to immobilize the tag on a substrate surface. The optical tag is bound to a probe and includes a plurality of pores that create an effective index of refraction. The plurality of pores and a thickness of the tag are selected for a reflectance property. The substrate is configured to contact a sample suspected of comprising an analyte. The probe is capable of binding specifically to the analyte. The reader is configured to expose the tag to light to generate a sample spectral signature that is a function of the effective index of refraction, the thickness of the optical tag, and whether the analyte is coupled to the probe. The sample spectral signature is compared to a reference to detect the analyte in the sample.

Abstract: A system for wide-range spectral measurement includes one or more broadband sources, an adjustable Fabry-Perot etalon, and a detector. The one or more broadband sources is to illuminate a sample, wherein the one or more broadband sources have a short broadband source coherence length. The adjustable Fabry-Perot etalon is to optically process the reflected light to extract spectral information with fine spectral resolution. The detector is to detect reflected light from the sample, wherein the reflected light is comprised of multiple narrow-band subsets of the illumination light having long coherence lengths and is optically processed using a plurality of settings for the adjustable Fabry-Perot etalon, and wherein the plurality of settings includes a separation of the Fabry-Perot etalon plates that is greater than the broadband source coherence length.

Abstract: A system for determining a calibrated spectral measurement includes a tunable Fabry-Perot etalon, a detector, and a processor. The tunable Fabry-Perot etalon has a settable gap. The detector measures light intensity. The processor is configured to determine the calibrated spectral measurement. The calibrated spectral measurement is based at least in part on a measurement set of detected light intensities for a plurality of settable gaps and a reconstruction matrix. The reconstruction matrix is based at least in part on calibration measurements. For a calibration measurement, a settable gap is selected and a set of input monochromatic source wavelengths is used to measure responses at a detector after transmission through the Fabry-Perot etalon. Each input monochromatic source wavelength is also measured using a radiometer to scale detector measurements.

Abstract: An integrated device including a photodetector, a transparent substrate, and one or more spacers. The photodetector is formed in a portion of a wafer. The one or more spacers separate the photodetector and the transparent substrate.

Abstract: A system for spectral reading includes a plurality of LEDs, an interface, and a processor. The plurality of LEDs are disposed in a physical array. Light from the plurality of LEDs is enabled to be collimated at a Fabry-Perot etalon. The interface is configured to receive a gap calibration table and power characteristics of a plurality of LEDs. The processor is configured to determine an LED switch table. The LED switch table indicates a set of the plurality of LEDs with power above a threshold at a plurality of wavelengths. The processor is further configured to cause measurement of a sample using the gap calibration table and the LED switch table for a set of gap values and determine measurement results.

Abstract: A system for machine vision spectral imaging includes a spectral imager, a substrate, and a processor. The spectral imager comprises a Fabry-Perot etalon including a settable gap. The substrate has relative motion with respect to the spectral imager. The processor is configured to identify an object in a set of images from the spectral imager, wherein each of the set of images is associated with a specific gap of a full set of gaps, wherein the full set of gaps comprises a set of gaps setting the settable gap covering a complete range of the settable gap needed for a full spectral image of the object.

Abstract: A system for determining a calibrated spectral measurement includes a tunable Fabry-Perot etalon, a detector, and a processor. The tunable Fabry-Perot etalon has a settable gap. The detector measures light intensity transmitted through the tunable Fabry-Perot etalon. The processor is configured to determine the calibrated spectral measurement. The calibrated spectral measurement is based at least in part on a measurement set of detected light intensities for a plurality of settable gaps and a reconstruction matrix. The reconstruction matrix is based at least in part on calibration measurements using multiple source wavelengths and multiple settable gaps.

Abstract: A device for identification of a tagged liquid includes a liquid access port, a powder access port, a filter and an optical analyzer. The liquid access port is for receiving a liquid. The powder access port is for receiving a powder. The powder includes tags. The filter is for separating one or more tags from a solution of the liquid mixed with the powder. The optical analyzer is for evaluating the one or more tags to verify the solution.

Abstract: A system for generating an item includes an input receiver and an additive manufacturing device. The input receiver is to receive an additive manufacturing material and a plurality of tags. The additive manufacturing device is to generate an additive manufacturing item using the additive manufacturing material and the plurality of tags.

Abstract: A system for wide-range spectral measurement includes one or more broadband sources, an adjustable Fabry-Perot etalon, and a detector. The one or more broadband sources is to illuminate a sample, wherein the one or more broadband sources have a short broadband source coherence length. The adjustable Fabry-Perot etalon is to optically process the reflected light to extract spectral information with fine spectral resolution. The detector is to detect reflected light from the sample, wherein the reflected light is comprised of multiple narrow-band subsets of the illumination light having long coherence lengths and is optically processed using a plurality of settings for the adjustable Fabry-Perot etalon, and wherein the plurality of settings includes a separation of the Fabry-Perot etalon plates that is greater than the broadband source coherence length.

Abstract: Provided herein are compositions, systems, and methods for performing a biological or chemical analysis of a sample using encoded functionalized optical tags. These optical tags can generate a unique spectral signature correlated with the identity of a probe bound to the optical tag, and a state of the interaction of the probe with an analyte. Also provided herein are methods of generating encoded functionalized optical tags.

Abstract: A system for spectral reading includes a plurality of LEDs, an interface, and a processor. The plurality of LEDs are disposed in a physical array. Light from the plurality of LEDs is enabled to be collimated at a Fabry-Perot etalon. The interface is configured to receive a gap calibration table and power characteristics of a plurality of LEDs. The processor is configured to determine an LED switch table. The LED switch table indicates a set of the plurality of LEDs with power above a threshold at a plurality of wavelengths. The processor is further configured to cause measurement of a sample using the gap calibration table and the LED switch table for a set of gap values and determine measurement results.

Abstract: A system for wide-range spectral measurement includes one or more broadband sources, an adjustable Fabry-Perot etalon, and a detector. The one or more broadband sources is to illuminate a sample, wherein the one or more broadband sources have a short broadband source coherence length. The adjustable Fabry-Perot etalon is to optically process the reflected light to extract spectral information with fine spectral resolution. The detector is to detect reflected light from the sample, wherein the reflected light is comprised of multiple narrow-band subsets of the illumination light having long coherence lengths and is optically processed using a plurality of settings for the adjustable Fabry-Perot etalon, and wherein the plurality of settings includes a separation of the Fabry-Perot etalon plates that is greater than the broadband source coherence length but that is less than the long coherence lengths.

Abstract: Biosensor including a device base having a sensor array of light sensors and a guide array of light guides. The light guides have input regions that are configured to receive excitation light and light emissions generated by biological or chemical substances. The light guides extend into the device base toward corresponding light sensors and have a filter material. The device base includes device circuitry electrically coupled to the light sensors and configured to transmit data signals. The biosensor also includes a shield layer having apertures that are positioned relative to the input regions of corresponding light guides such that the light emissions propagate through the apertures into the corresponding input regions. The shield layer extends between adjacent apertures and is configured to block the excitation light and the light emissions incident on the shield layer between the adjacent apertures.

Abstract: A device for tunable optical filter includes a substrate, one or more piezos, a bottom mirror, and a top mirror. The one or more piezos are placed on the substrate. The one or more piezos have a piezo thickness. The bottom mirror is placed on the substrate. The bottom mirror has a bottom mirror thickness greater than the piezo thickness. The top mirror is placed on the bottom mirror. The top mirror is attached to the one or more piezos.

Abstract: Optical interference filters associated with specific, unique signatures are applied to medical consumables in order to label them. The interactions of those optical interface filters with electromagnetic waves can be observed in order to determine those unique signatures. These unique signatures can be used to look up entries in a database that contain information associated with the tagged medical consumable, allowing for the medical consumable to be easily identified and verified. Various systems and methods are provided herein that utilize these optical interference filters for performing medication reconciliation and tracking patient compliance to prescribed drug schedules, which can greatly reduce the errors and costs associated with medication reconciliation and monitoring patient compliance.

Abstract: A system for wide-range spectral measurement includes one or more broadband sources, an adjustable Fabry-Perot etalon, and a detector. The one or more broadband sources is to illuminate a sample, wherein the one or more broadband sources have a short broadband source coherence length. The adjustable Fabry-Perot etalon is to optically process the reflected light to extract spectral information with fine spectral resolution. The detector is to detect reflected light from the sample, wherein the reflected light is comprised of multiple narrow-band subsets of the illumination light having long coherence lengths and is optically processed using a plurality of settings for the adjustable Fabry-Perot etalon, and wherein the plurality of settings includes a separation of the Fabry-Perot etalon plates that is greater than the broadband source coherence length but that is less than the long coherence lengths.

Abstract: An integrated detection, flow cell and photonics (DFP) device is provided that comprises a substrate having an array of pixel elements that sense photons during active periods. The substrate and pixel elements form an IC photon detection layer. At least one wave guide is formed on the IC photo detection layer as a photonics layer. An optical isolation layer is formed over at least a portion of the wave guide. A collection of photo resist (PR) walls patterned to define at least one flow cell channel that is configured to direct fluid along a fluid flow path. The wave guides align to extend along the fluid flow path. The flow cell channel is configured to receive samples at sample sites that align with the array of pixel elements.

Abstract: Techniques and apparatus for using single photon avalanche diode (SPAD) devices in various applications.