Patents by Inventor Hoi Young Lee

Hoi Young Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apicidin-derivatives, their synthetic methods and anti-tumor compositions containing them
    Patent number: 6831061
    Abstract: A substituted apicidin derivative, a method of synthesis therefore, and an anti-tumor composition comprising the same are disclosed. The substituent of the derivative is preferably semicarbazone, thiosemicarbazone, hydrazone, tert-butylhydrazone, phenylhydrazone, 2,4-dinitrophenylhydrazone, 4-methoxyphenylhydrazone, 3-methoxyphenylhydrazone, 4-nitrophenylhydrazone, benzylhydrazone, methanesulfonylhydrazone, benzenesulfonylhydrazone, 4-methylbenzenesulfonylhydrazone, benzoylhydrazone, 4-nitrobenzoylhydrazone, carbohydrazone, benzyloxime or acetoxime. The compound has strong inhibition effect against histone deacetylase and detransforming activities and specifically inhibit growth of cancer cells. Therefore, it is useful in preparation of an anti-tumor composition.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: December 14, 2004
    Inventors: Hyang Woo Lee, Young Hoon Jung, Jeung Whan Han, Seok Yong Lee, Yin Won Lee, Hoi Young Lee
  • Apicidin-derivatives, their synthetic methods and anti-tumor compositions containing them
    Publication number: 20040014647
    Abstract: A substituted apicidin derivative, a method of synthesis therefore, and an anti-tumor composition comprising the same are disclosed. The substituent of the derivative is preferably semicarbazone, thiosemicarbazone, hydrazone, tert-butylhydrazone, phenylhydrazone, 2,4-dinitrophenylhydrazone, 4-methoxyphenylhydrazone, 3-methoxyphenylhydrazone, 4-nitrophenylhydrazone, benzylhydrazone, methanesulfonylhydrazone, benzenesulfonylhydrazone, 4-methylbenzenesulfonylhydrazone, benzoylhydrazone, 4-nitrobenzoylhydrazone, carbohydrazone, benzyloxime or acetoxime. The compound has strong inhibition effect against histone deacetylase and detransforming activities and specifically inhibit growth of cancer cells. Therefore, it is useful in preparation of an anti-tumor composition.
    Type: Application
    Filed: June 20, 2003
    Publication date: January 22, 2004
    Inventors: Hyang Woo Lee, Young Hoon Jung, Jeung Whan Han, Seok Yong Lee, Yin Won Lee, Hoi Young Lee