Abstract: A method and system are provided for acquiring and combining images captured by a microscope. The method comprises: capturing a new image from the microscope using an imaging device; comparing the new image against a previous image to provide an estimated position of the new image; identifying neighboring key frames of a scan stored in memory based on the estimated position of the new image; comparing the new image to the identified key frames to determine a relative displacement of the new image from the neighboring key frames; and determining a position of the new image based on the relative displacement of the new image. The system includes: a microscope; a camera coupled to the microscope for capturing images through the microscope; and a computing device coupled to the camera, the computing device comprising: a memory; and a processor configured and adapted to perform a method as described herein.

Abstract: A microscopy imaging system and method for rendering a mosaic representation of an object from a series of image frames of the object are disclosed. A current image frame is processed to determine its relative location or position within the mosaic representation based on relative displacement of the current image from one or more keyframes. Once the current image frame's position has been determined, it is rendered along with its neighboring keyframes to provide the mosaic representation of the object.

Abstract: A microscopy imaging system and method for rendering a mosaic representation of an object from a series of image frames of the object are disclosed. A current image frame is processed to determine its relative location or position within the mosaic representation based on relative displacement of the current image from one or more keyframes. Once the current image frame's position has been determined, it is rendered along with its neighboring keyframes to provide the mosaic representation of the object.