Patents by Inventor Ho-Koon Park

Ho-Koon Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-(phenylamino)-[1,4]dioxano[2,3-g]quinazoline derivatives and process for preparing the same
    Patent number: 6835735
    Abstract: The present invention relates to 4-(phenylamino)-[1,4]dioxano[2,3-g]quinazoline derivatives which inhibit tyrosine kinase of epidermal growth factor receptor(EGFR), and pharmaceutically acceptable salts, hydrates and solvates thereof, and a process for preparing the same. Since 4-(phenylamino)-[1,4]dioxano[2,3-g]quinazoline derivatives of the invention have a high solubility in water and inhibit the activity of EGFR tyrosine kinase and the growth of cancer cells, they can be practically applied in the treatment of overproliferation-associated diseases such as cancer.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: December 28, 2004
    Assignee: Korea Institute of Science and Technology
    Inventors: Yong-Sup Lee, Ho-Koon Park, Jae-Yeol Lee, Beom-Seok Yang, Seon-Hee Seo
  • 4-(Phenylamino)-[1,4]dioxano[2,3-g]quinazoline derivatives and process for preparing the same
    Publication number: 20030045537
    Abstract: The present invention relates to 4-(phenylamino)-[1,4]dioxano[2,3-g]quinazoline derivatives which inhibit tyrosine kinase of epidermal growth factor receptor (EGFR), and pharmaceutically acceptable salts, hydrates and solvates thereof, and a process for preparing the same. Since 4-(phenylamino)-[1,4]dioxano[2,3-g]quinazoline derivatives of the invention have a high solubility in water and inhibit the activity of EGFR tyrosine kinase and the growth of cancer cells, they can be practically applied in the treatment of overproliferation-associated diseases such as cancer.
    Type: Application
    Filed: March 11, 2002
    Publication date: March 6, 2003
    Inventors: Yong-Sup Lee, Ho-Koon Park, Jae-Yeol Lee, Beom-Seok Yang, Seon-Hee Seo