Patents by Inventor Holden Terry Maecker

Holden Terry Maecker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Profiling and treatment of MYC-associated cancers with NK cells and type 1 interferon
    Patent number: 11648275
    Abstract: Compositions and methods are provided for classification and treatment of MYC-driven cancers, i.e. causally dependent on MYC as a result of, over-expression of MYC, constitutive expression of MYC, chromosomal translocation resulting in overactive MYC, and the like. Specifically, the methods comprising determining the MYC status of the cancer, and in a cancer that is determined to be driven by MYC activation, administering a composition of an effective dose of one or both of activated natural killer (NK) cells and a type 1 interferon.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: May 16, 2023
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Srividya Swaminathan, Dean W. Felsher, Holden Terry Maecker
  • PROFILING AND TREATMENT OF MYC-ASSOCIATED CANCERS
    Publication number: 20200353000
    Abstract: Compositions and methods are provided for classification and treatment of MYC-driven cancers, i.e. causally dependent on MYC as a result of, over-expression of MYC, constitutive expression of MYC, chromosomal translocation resulting in overactive MYC, and the like. Specifically, the methods comprising determining the MYC status of the cancer, and in a cancer that is determined to be driven by MYC activation, administering a composition of an effective dose of one or both of activated natural killer (NK) cells and a type 1 interferon.
    Type: Application
    Filed: December 12, 2018
    Publication date: November 12, 2020
    Inventors: Srividya Swaminathan, Dean W. Felsher, Holden Terry Maecker
  • Platinum-labeled probes for mass cytometry
    Patent number: 10215758
    Abstract: The present disclosure provides analyte-specific binding reagents conjugated with a platinum-containing moiety, e.g., cisplatin, and methods, compositions, and kits for their production and use in assays for analyte detection.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: February 26, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Holden Terry Maecker, Michael Duane Leipold, Henrik Mei
  • PLATINUM-LABELED PROBES FOR MASS CYTOMETRY
    Publication number: 20170059574
    Abstract: The present disclosure provides analyte-specific binding reagents conjugated with a platinum-containing moiety, e.g., cisplatin, and methods, compositions, and kits for their production and use in assays for analyte detection.
    Type: Application
    Filed: August 8, 2016
    Publication date: March 2, 2017
    Inventors: Holden Terry Maecker, Michael Duane Leipold, Henrik Mei