Patents by Inventor Holger Bartos
Holger Bartos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11298295Abstract: A system and a method for medication adherence management with which a medicament container is held by a holding apparatus, a detector device wirelessly recognizes an opening and closing activity of the medicament container, and a data processing device or control device reads and processes data of the detector device.Type: GrantFiled: October 9, 2017Date of Patent: April 12, 2022Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventor: Holger Bartos
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Publication number: 20190307648Abstract: A system and a method for medication adherence management with which a medicament container is held by a holding apparatus, a detector device wirelessly recognizes an opening and closing activity of the medicament container, and a data processing device or control device reads and processes data of the detector device.Type: ApplicationFiled: October 9, 2017Publication date: October 10, 2019Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventor: Holger BARTOS
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Patent number: 10363559Abstract: The invention relates to an apparatus for separating blood and at the same time an apparatus (1) for absorbing blood (19) and separating components such as blood plasma, as a sample liquid (2), having a feed device (13) for receiving the blood (2), a separating device (15) for separating blood components as the sample liquid (2), a channel (3) which takes up the sample liquid (2) preferably exclusively by capillary forces and a fill device for filling the channel (3) with sample liquid (2) in an inlet or feed region (18) of the channel (3), wherein the separating device (15), particularly a membrane, is domed, more particularly convexly shaped and projects with the apex of the convex shape into the filling device in the direction of filling.Type: GrantFiled: November 22, 2016Date of Patent: July 30, 2019Assignee: Boehringer Ingelheim International GmbHInventors: Gert Blankenstein, Holger Bartos, Ralf-Peter Peters, Christian Schoen
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Publication number: 20170165666Abstract: The invention relates to an apparatus for separating blood and at the same time an apparatus (1) for absorbing blood (19) and separating components such as blood plasma, as a sample liquid (2), having a feed device (13) for receiving the blood (2), a separating device (15) for separating blood components as the sample liquid (2), a channel (3) which takes up the sample liquid (2) preferably exclusively by capillary forces and a fill device for filling the channel (3) with sample liquid (2) in an inlet or feed region (18) of the channel (3), wherein the separating device (15), particularly a membrane, is domed, more particularly convexly shaped and projects with the apex of the convex shape into the filling device in the direction of filling.Type: ApplicationFiled: November 22, 2016Publication date: June 15, 2017Inventors: Gert BLANKENSTEIN, Holger BARTOS, Ralf-Peter PETERS, Christian SCHOEN
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Patent number: 9539572Abstract: The invention relates to an apparatus for separating blood, more particularly an apparatus (1) for absorbing blood (19) and separating blood components, e.g. blood plasma, as a sample liquid (2). Said apparatus (1) comprises a feeding device (13) for absorbing the blood (2), a device (15) for separating blood components as a sample liquid (2), a duct which preferably absorbs the sample liquid (2) exclusively by means of capillary forces, and a device for filling the duct (3) with sample liquid (2) in an inlet or feeding zone (18) of the duct (3). The separating device (15), in particular a membrane, is curved, especially convexly shaped, and the apex of said curved, especially convex shape projects into the filling device.Type: GrantFiled: February 26, 2009Date of Patent: January 10, 2017Assignee: Boehringer Ingelheim Microparts GmbHInventors: Gert Blankenstein, Holger Bartos, Ralf-Peter Peters, Christian Schoen
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Patent number: 8741136Abstract: The invention relates to a device and a method for cleaning sample material, in particular nucleic acids. The cleaning process takes place by means of centrifugal microfluidics and the invention provides a simple compact construction and a simple procedure. If necessary, the sample material is easily mixed with a solvent buffer and proteases in the device. The cleaned sample material is in particular transferred directly to a container. Separate containers for the removal of excess liquid are not required.Type: GrantFiled: February 7, 2007Date of Patent: June 3, 2014Assignee: Boehringer Ingelheim Microparts GmbHInventors: Ralf-Peter Peters, Holger Bartos
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Patent number: 8337775Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.Type: GrantFiled: September 8, 2008Date of Patent: December 25, 2012Assignee: Siemens Healthcare Diagnostics, Inc.Inventors: Michael J. Pugia, Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
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Patent number: 8318110Abstract: Holding device for the arrangement of at least one optical component in front of a laser light source of a laser unit, including a first holding part to which at least one optical component is attached, the holding device furthermore including a second holding part which is attached to one part of the laser unit, and the first holding part being attached to the second holding part. Furthermore this invention relates to an arrangement with such a holding device and a process for producing this arrangement.Type: GrantFiled: March 14, 2011Date of Patent: November 27, 2012Assignee: Boehringer Ingelheim microParts GmbHInventors: Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
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Patent number: 8231845Abstract: The present invention relates to devices for efficient transport, transfer and movement of fluids. In particular, the invention provides fluidic micro-structures for controlled transport and movement of liquids in devices for analytical and other purposes. Devices of the invention include one or more features that can enhance performance of the fluid transfer, referred to as a pre-shooter stop, a butterfly structure, a cascade structure, a waste chamber inlet, a capillary driven sample inlet chamber, a capillary stop structure, a bifurcation flow-through structure, and a hydrophobic vent.Type: GrantFiled: July 6, 2004Date of Patent: July 31, 2012Assignee: Steag MicropartsInventors: Raimund C. Wyzgol, Holger Bartos, Ralf-Peter Peters, Christian Schön, Dirk Osterloh, Gert Blankenstein
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Publication number: 20110172109Abstract: Holding device for the arrangement of at least one optical component in front of a laser light source of a laser unit, including a first holding part to which at least one optical component is attached, the holding device furthermore including a second holding part which is attached to one part of the laser unit, and the first holding part being attached to the second holding part. Furthermore this invention relates to an arrangement with such a holding device and a process for producing this arrangement.Type: ApplicationFiled: March 14, 2011Publication date: July 14, 2011Inventors: Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
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Patent number: 7931868Abstract: Device for manipulation of limited quantities of liquids with the following features: the device has at least one solid; the solid has surface areas in which different capillary forces act; one or more first surface areas have a microstructured and/or nanostructured surface; the microstructured and/or nanostructured surfaces have regularly arranged structure elements (A to E); the solid and the structure elements consist of one material and are connected to one another in one piece; one or more first surface areas are provided with reagents; the second surface area encompasses at least one of the first surface areas.Type: GrantFiled: June 10, 2004Date of Patent: April 26, 2011Assignee: Steag Microparts GmbHInventors: Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
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Publication number: 20110088786Abstract: A method for manipulating a first liquid within a device including fabricated microstructures for transporting the first liquid through a system of capillary channels and cavities with a closed configuration. The method including transporting the first liquid through the system by capillary force only, stopping a flow of the first liquid temporarily at a capillary stop, switching on the flow of the first liquid after a desired stop time is elapsed, adjusting the stop time of the first liquid by a length and a cross-section of the control capillary between a beginning of the control capillary and its end at the capillary stop, metering the first liquid to be manipulated, and holding a metered amount of the first liquid during the stop time within a cavity.Type: ApplicationFiled: December 23, 2010Publication date: April 21, 2011Applicant: Boehringer Ingelheim microParts GmbHInventors: Gert BLANKENSTEIN, Thomas Willms, Ralf-Peter Peters, Claus Marquordt, Holger Bartos
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Publication number: 20110011781Abstract: The invention relates to an apparatus for separating blood, more particularly an apparatus (1) for absorbing blood (19) and separating blood components, e.g. blood plasma, as a sample liquid (2). Said apparatus (1) comprises a feeding device (13) for absorbing the blood (2), a device (15) for separating blood components as a sample liquid (2), a duct which preferably absorbs the sample liquid (2) exclusively by means of capillary forces, and a device for filling the duct (3) with sample liquid (2) in an inlet or feeding zone (18) of the duct (3). The separating device (15), in particular a membrane, is curved, especially convexly shaped, and the apex of said curved, especially convex shape projects into the filling device.Type: ApplicationFiled: February 26, 2009Publication date: January 20, 2011Applicant: BOEHRINGER INGELHEIM MICROPARTS GMBHInventors: Gert Blankenstein, Holger Bartos, Ralf-Peter Peters, Christian Schoen
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Publication number: 20090209752Abstract: The invention relates to a device and a method for cleaning sample material, in particular nucleic acids. The cleaning process takes place by means of centrifugal microfluidics and the invention provides a simple compact construction and a simple procedure. If necessary, the sample material is easily mixed with a solvent buffer and proteases in the device. The cleaned sample material is in particular transferred directly to a container. Separate containers for the removal of excess liquid are not required.Type: ApplicationFiled: February 7, 2007Publication date: August 20, 2009Inventors: Ralf-Peter Peters, Holger Bartos
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Publication number: 20090004059Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.Type: ApplicationFiled: September 8, 2008Publication date: January 1, 2009Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Michael J. Pugia, Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
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Patent number: 7459127Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.Type: GrantFiled: February 26, 2002Date of Patent: December 2, 2008Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Michael J. Pugia, Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
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Patent number: 7357016Abstract: A process and a device for determining the viscosity of a fluid are proposed. Very simple and accurate determination is enabled in that the magnetic particles in the fluid are set into vibration by a magnetic field which varies over time. A measurement of the amplitude and/or phase of particle vibration is used to determine the viscosity or an associated quantity, such as the coagulation of blood or the glucose content.Type: GrantFiled: December 17, 2004Date of Patent: April 15, 2008Assignee: Boehringer Ingelheim microParts GmbHInventors: Dirk Kurowski, Christian Schoen, Ralf-Peter Peters, Holger Bartos, Ying Yu
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Patent number: 7134453Abstract: The invention relates to a microfluidic switch for stopping a liquid flow during a time interval with the following features: the switch has at least one first channel and at least one second channel; the first channel and the second channel have a common end area; the first channel in the end area has a stopping mechanism for stopping of a liquid flow flowing in the first channel; the stopping mechanism can be controlled by means of a liquid flow flowing in the second channel for continuing the liquid flow in the first channel. Transport in the first and the second channel takes place advantageously by the capillarity acting in the channel.Type: GrantFiled: January 23, 2004Date of Patent: November 14, 2006Assignee: Boehringer Ingelheim Microparts GmbHInventors: Ralf Peters, Gert Blankenstein, Holger Bartos, Claus Marquordt
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Patent number: 7036917Abstract: A device for parallel metering of a liquid with the following features: the device has a first body; the first body has a main channel, secondary channels, one inlet and outlets; the main channel is connected to the inlet; the secondary channels are connected to one outlet at a time; the secondary channels are connected to the main channel; the device has at least one first chamber with a first pressure medium; the first body has means for transferring transfer means pressure surges of the pressure medium from a first chamber to the secondary channels; each transfer means is connected to a secondary channel; and at least one means for preventing a fluidic connection between the secondary channels and the chamber is assigned to the transfer means.Type: GrantFiled: December 5, 2003Date of Patent: May 2, 2006Assignee: Steag Microparts GmbHInventors: Birgit Müller-Chorus, Ralf-Peter Peters, Holger Bartos
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Publication number: 20050249641Abstract: A microstructured platform for manipulating a wetting liquid including at least one cavity and a channel system for transporting the liquid. At least some of the channels of the channel system are made as capillaries which have a dimension in the millimeter range or less in at least one direction transverse to the transport direction of the liquid. The platform also includes at least one other microstuctured element disposed in the transport path of the liquid. The microstructured element may be in the form of a fluidic switch, metering means, separating device, or a region for holding together a limited amount of liquid. The structure facilitates or enables the manipulation of liquids when only a small amount of liquid is available and extensive analyses are to be performed with the liquid.Type: ApplicationFiled: April 8, 2005Publication date: November 10, 2005Applicant: Boehringer Ingelheim microParts GmbHInventors: Gert Blankenstein, Thomas Willms, Ralf-Peter Peters, Claus Marquordt, Holger Bartos