Patents by Inventor Holger Bartos

Holger Bartos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11298295
    Abstract: A system and a method for medication adherence management with which a medicament container is held by a holding apparatus, a detector device wirelessly recognizes an opening and closing activity of the medicament container, and a data processing device or control device reads and processes data of the detector device.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: April 12, 2022
    Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventor: Holger Bartos
  • Publication number: 20190307648
    Abstract: A system and a method for medication adherence management with which a medicament container is held by a holding apparatus, a detector device wirelessly recognizes an opening and closing activity of the medicament container, and a data processing device or control device reads and processes data of the detector device.
    Type: Application
    Filed: October 9, 2017
    Publication date: October 10, 2019
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventor: Holger BARTOS
  • Patent number: 10363559
    Abstract: The invention relates to an apparatus for separating blood and at the same time an apparatus (1) for absorbing blood (19) and separating components such as blood plasma, as a sample liquid (2), having a feed device (13) for receiving the blood (2), a separating device (15) for separating blood components as the sample liquid (2), a channel (3) which takes up the sample liquid (2) preferably exclusively by capillary forces and a fill device for filling the channel (3) with sample liquid (2) in an inlet or feed region (18) of the channel (3), wherein the separating device (15), particularly a membrane, is domed, more particularly convexly shaped and projects with the apex of the convex shape into the filling device in the direction of filling.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: July 30, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Gert Blankenstein, Holger Bartos, Ralf-Peter Peters, Christian Schoen
  • Publication number: 20170165666
    Abstract: The invention relates to an apparatus for separating blood and at the same time an apparatus (1) for absorbing blood (19) and separating components such as blood plasma, as a sample liquid (2), having a feed device (13) for receiving the blood (2), a separating device (15) for separating blood components as the sample liquid (2), a channel (3) which takes up the sample liquid (2) preferably exclusively by capillary forces and a fill device for filling the channel (3) with sample liquid (2) in an inlet or feed region (18) of the channel (3), wherein the separating device (15), particularly a membrane, is domed, more particularly convexly shaped and projects with the apex of the convex shape into the filling device in the direction of filling.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 15, 2017
    Inventors: Gert BLANKENSTEIN, Holger BARTOS, Ralf-Peter PETERS, Christian SCHOEN
  • Patent number: 9539572
    Abstract: The invention relates to an apparatus for separating blood, more particularly an apparatus (1) for absorbing blood (19) and separating blood components, e.g. blood plasma, as a sample liquid (2). Said apparatus (1) comprises a feeding device (13) for absorbing the blood (2), a device (15) for separating blood components as a sample liquid (2), a duct which preferably absorbs the sample liquid (2) exclusively by means of capillary forces, and a device for filling the duct (3) with sample liquid (2) in an inlet or feeding zone (18) of the duct (3). The separating device (15), in particular a membrane, is curved, especially convexly shaped, and the apex of said curved, especially convex shape projects into the filling device.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: January 10, 2017
    Assignee: Boehringer Ingelheim Microparts GmbH
    Inventors: Gert Blankenstein, Holger Bartos, Ralf-Peter Peters, Christian Schoen
  • Patent number: 8741136
    Abstract: The invention relates to a device and a method for cleaning sample material, in particular nucleic acids. The cleaning process takes place by means of centrifugal microfluidics and the invention provides a simple compact construction and a simple procedure. If necessary, the sample material is easily mixed with a solvent buffer and proteases in the device. The cleaned sample material is in particular transferred directly to a container. Separate containers for the removal of excess liquid are not required.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: June 3, 2014
    Assignee: Boehringer Ingelheim Microparts GmbH
    Inventors: Ralf-Peter Peters, Holger Bartos
  • Patent number: 8337775
    Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: December 25, 2012
    Assignee: Siemens Healthcare Diagnostics, Inc.
    Inventors: Michael J. Pugia, Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
  • Patent number: 8318110
    Abstract: Holding device for the arrangement of at least one optical component in front of a laser light source of a laser unit, including a first holding part to which at least one optical component is attached, the holding device furthermore including a second holding part which is attached to one part of the laser unit, and the first holding part being attached to the second holding part. Furthermore this invention relates to an arrangement with such a holding device and a process for producing this arrangement.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: November 27, 2012
    Assignee: Boehringer Ingelheim microParts GmbH
    Inventors: Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
  • Patent number: 8231845
    Abstract: The present invention relates to devices for efficient transport, transfer and movement of fluids. In particular, the invention provides fluidic micro-structures for controlled transport and movement of liquids in devices for analytical and other purposes. Devices of the invention include one or more features that can enhance performance of the fluid transfer, referred to as a pre-shooter stop, a butterfly structure, a cascade structure, a waste chamber inlet, a capillary driven sample inlet chamber, a capillary stop structure, a bifurcation flow-through structure, and a hydrophobic vent.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: July 31, 2012
    Assignee: Steag Microparts
    Inventors: Raimund C. Wyzgol, Holger Bartos, Ralf-Peter Peters, Christian Schön, Dirk Osterloh, Gert Blankenstein
  • Publication number: 20110172109
    Abstract: Holding device for the arrangement of at least one optical component in front of a laser light source of a laser unit, including a first holding part to which at least one optical component is attached, the holding device furthermore including a second holding part which is attached to one part of the laser unit, and the first holding part being attached to the second holding part. Furthermore this invention relates to an arrangement with such a holding device and a process for producing this arrangement.
    Type: Application
    Filed: March 14, 2011
    Publication date: July 14, 2011
    Inventors: Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
  • Patent number: 7931868
    Abstract: Device for manipulation of limited quantities of liquids with the following features: the device has at least one solid; the solid has surface areas in which different capillary forces act; one or more first surface areas have a microstructured and/or nanostructured surface; the microstructured and/or nanostructured surfaces have regularly arranged structure elements (A to E); the solid and the structure elements consist of one material and are connected to one another in one piece; one or more first surface areas are provided with reagents; the second surface area encompasses at least one of the first surface areas.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: April 26, 2011
    Assignee: Steag Microparts GmbH
    Inventors: Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
  • Publication number: 20110088786
    Abstract: A method for manipulating a first liquid within a device including fabricated microstructures for transporting the first liquid through a system of capillary channels and cavities with a closed configuration. The method including transporting the first liquid through the system by capillary force only, stopping a flow of the first liquid temporarily at a capillary stop, switching on the flow of the first liquid after a desired stop time is elapsed, adjusting the stop time of the first liquid by a length and a cross-section of the control capillary between a beginning of the control capillary and its end at the capillary stop, metering the first liquid to be manipulated, and holding a metered amount of the first liquid during the stop time within a cavity.
    Type: Application
    Filed: December 23, 2010
    Publication date: April 21, 2011
    Applicant: Boehringer Ingelheim microParts GmbH
    Inventors: Gert BLANKENSTEIN, Thomas Willms, Ralf-Peter Peters, Claus Marquordt, Holger Bartos
  • Publication number: 20110011781
    Abstract: The invention relates to an apparatus for separating blood, more particularly an apparatus (1) for absorbing blood (19) and separating blood components, e.g. blood plasma, as a sample liquid (2). Said apparatus (1) comprises a feeding device (13) for absorbing the blood (2), a device (15) for separating blood components as a sample liquid (2), a duct which preferably absorbs the sample liquid (2) exclusively by means of capillary forces, and a device for filling the duct (3) with sample liquid (2) in an inlet or feeding zone (18) of the duct (3). The separating device (15), in particular a membrane, is curved, especially convexly shaped, and the apex of said curved, especially convex shape projects into the filling device.
    Type: Application
    Filed: February 26, 2009
    Publication date: January 20, 2011
    Applicant: BOEHRINGER INGELHEIM MICROPARTS GMBH
    Inventors: Gert Blankenstein, Holger Bartos, Ralf-Peter Peters, Christian Schoen
  • Publication number: 20090209752
    Abstract: The invention relates to a device and a method for cleaning sample material, in particular nucleic acids. The cleaning process takes place by means of centrifugal microfluidics and the invention provides a simple compact construction and a simple procedure. If necessary, the sample material is easily mixed with a solvent buffer and proteases in the device. The cleaned sample material is in particular transferred directly to a container. Separate containers for the removal of excess liquid are not required.
    Type: Application
    Filed: February 7, 2007
    Publication date: August 20, 2009
    Inventors: Ralf-Peter Peters, Holger Bartos
  • Publication number: 20090004059
    Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.
    Type: Application
    Filed: September 8, 2008
    Publication date: January 1, 2009
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Michael J. Pugia, Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
  • Patent number: 7459127
    Abstract: A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: December 2, 2008
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Michael J. Pugia, Gert Blankenstein, Ralf-Peter Peters, Holger Bartos
  • Patent number: 7357016
    Abstract: A process and a device for determining the viscosity of a fluid are proposed. Very simple and accurate determination is enabled in that the magnetic particles in the fluid are set into vibration by a magnetic field which varies over time. A measurement of the amplitude and/or phase of particle vibration is used to determine the viscosity or an associated quantity, such as the coagulation of blood or the glucose content.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: April 15, 2008
    Assignee: Boehringer Ingelheim microParts GmbH
    Inventors: Dirk Kurowski, Christian Schoen, Ralf-Peter Peters, Holger Bartos, Ying Yu
  • Patent number: 7134453
    Abstract: The invention relates to a microfluidic switch for stopping a liquid flow during a time interval with the following features: the switch has at least one first channel and at least one second channel; the first channel and the second channel have a common end area; the first channel in the end area has a stopping mechanism for stopping of a liquid flow flowing in the first channel; the stopping mechanism can be controlled by means of a liquid flow flowing in the second channel for continuing the liquid flow in the first channel. Transport in the first and the second channel takes place advantageously by the capillarity acting in the channel.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: November 14, 2006
    Assignee: Boehringer Ingelheim Microparts GmbH
    Inventors: Ralf Peters, Gert Blankenstein, Holger Bartos, Claus Marquordt
  • Patent number: 7036917
    Abstract: A device for parallel metering of a liquid with the following features: the device has a first body; the first body has a main channel, secondary channels, one inlet and outlets; the main channel is connected to the inlet; the secondary channels are connected to one outlet at a time; the secondary channels are connected to the main channel; the device has at least one first chamber with a first pressure medium; the first body has means for transferring transfer means pressure surges of the pressure medium from a first chamber to the secondary channels; each transfer means is connected to a secondary channel; and at least one means for preventing a fluidic connection between the secondary channels and the chamber is assigned to the transfer means.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: May 2, 2006
    Assignee: Steag Microparts GmbH
    Inventors: Birgit Müller-Chorus, Ralf-Peter Peters, Holger Bartos
  • Publication number: 20050249641
    Abstract: A microstructured platform for manipulating a wetting liquid including at least one cavity and a channel system for transporting the liquid. At least some of the channels of the channel system are made as capillaries which have a dimension in the millimeter range or less in at least one direction transverse to the transport direction of the liquid. The platform also includes at least one other microstuctured element disposed in the transport path of the liquid. The microstructured element may be in the form of a fluidic switch, metering means, separating device, or a region for holding together a limited amount of liquid. The structure facilitates or enables the manipulation of liquids when only a small amount of liquid is available and extensive analyses are to be performed with the liquid.
    Type: Application
    Filed: April 8, 2005
    Publication date: November 10, 2005
    Applicant: Boehringer Ingelheim microParts GmbH
    Inventors: Gert Blankenstein, Thomas Willms, Ralf-Peter Peters, Claus Marquordt, Holger Bartos