Abstract: The present invention refers to polyoxyalkylene based compounds and their manufacturing method as well as compositions containing at least one polyoxyalkylene based compound and at least one active agent. Furthermore, the present invention refers to the manufacture of the compositions of the present invention as well as their use for the treatment of an illness in mammals or humans.

Abstract: The present invention refers to polyoxyalkylene based compounds and their manufacturing method as well as compositions including at least one polyoxyalkylene based compound and at least one active agent. Furthermore, the present invention refers to the manufacture of the compositions of the present invention as well as their use for the treatment of an illness in mammals or humans.

Abstract: A process of making a functionalized diene polymer comprising subjecting a functionalized diene monomer to a polymerization reaction to produce a side-group functionalized polymer wherein the functionalized diene monomer is selected from the group according to formulae (1) to (3) or a combination thereof, wherein a1, a2, a3, a4, a5 independently from each other represent either H or a saturated, unsaturated, linear or branched aliphatic hydrocarbon residue having from 1 to 12 carbon atoms, with the proviso that at least three of a1, a2, a3, a4 and a5 represent H, and wherein X represents a side group according to formula (4): wherein in formula (4) n is selected from 0, 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10, A1, A2, A3, A4 are identical or different and represent oxygen or —NR10R11 wherein R10 and R11 are identical or different and represent a C1-C12 alkyl residue or an aromatic residue with 6 to 20 carbon atoms selected from aryl, alkylaryl or arylalkyl, and wherein at least one of A1 or A2 and at

Abstract: The invention relates to block copolymer comprising i) A first block wherein at least 65 mol-% of the repeating units of the first block are repeating units of the formula (I)—[CH2—CH2—O]—, ii) A second block wherein at least 90 mol-% of the repeating units of the second block are repeating units of at least one of formulae (II) or (III), wherein the groups R1, R2, and R3 independent of each occurrence are selected from hydrocarbyl groups having 1 to 40 carbon atoms, which are optionally substituted by ether or hydroxyl groups, and wherein the groups R1 and R2 are optionally linked to each other such that a nitrogen heterocyclic structure is present, iii) A third block which is different from the first block and the second block and which is more hydrophobic than the first block.

Abstract: Polyether polymers represented by the following formula [I]: —(CH2CHR—O—)m—??(I) wherein 10 to 90% of the residues R are hydrogen and 10% to 90% of the residues R are independently from each other selected from the group made of, methoxymethyl, ethoxymethyl, n-propoxymethyl and iso-propoxymethyl; 1 to 100% of the residues R are methoxymethyl; up to 50% of the residues R may be selected from the group made of ethoxymethyl, n-propoxymethyl and iso-propoxymethyl; and m is in the range of from 10 to 1000 and the dispersity is 1.15 or less. A process for their preparation, conjugates thereof and the use thereof.

Abstract: The present invention relates to methods of forming star polymers having configurable architecture in which arms are synthesized by means of living anionic polymerization, with the arms being conjugated with a core, the core comprising m coupling groups, each coupling group having n methylene groups. The invention further relates to star polymers produced therefrom.

Abstract: The invention relates to block copolymer comprising i) A first block wherein at least 65 mol-% of the repeating units of the first block are repeating units of the formula (I)—[CH2—CH2—O]—, ii) A second block wherein at least 90 mol-% of the repeating units of the second block are repeating units of at least one of formulae (II) or (III), wherein the groups R1, R2, and R3 independent of each occurrence are selected from hydrocarbyl groups having 1 to 40 carbon atoms, which are optionally substituted by ether or hydroxyl groups, and wherein the groups R1 and R2 are optionally linked to each other such that a nitrogen heterocyclic structure is present, iii) A third block which is different from the first block and the second block and which is more hydrophobic than the first block.

Abstract: The present invention relates to methods of forming star polymers having configurable architecture in which arms are synthesized by means of living anionic polymerization, with the arms being conjugated with a core, the core comprising m coupling groups, each coupling group having n methylene groups. The invention further relates to star polymers produced therefrom.

Abstract: The invention relates to a copolymer for galenic applications, having an acrylate backbone and sidearms, containing ?-hydroxycarboxylic acid groups. The invention further relates to the process of preparing the foregoing copolymer for galenic applications and its use thereof.

Abstract: The invention relates to a polymerization method in which alkyl glycidyl ethers and epoxides, such as ethylene oxide, polypropylene oxide, 1-ethoxyethyl glycidyl ether and gycidol, are copolymerized and block copolymers are synthesized. The inventive methods include an initiator, oligomer blocks of 1 to 40 alkyl glycidyl ether units of type (I), (II) or (III), and 80 to 1000 epoxy units of large polyether blocks, such as polyethylene oxide (PEO), polypropylene oxide (PPO), polyethoxyethylene glycidyl ether (PEEGE), linear and branched polyglycidol (PG, hbPG) or random copolymers of two, three or four different epoxide units, such as ethylene oxide (EO), propylene oxide (PO), 1-ethoxyethyl glycidyl ether (EEGE) and/or glycidol.

Abstract: The invention relates to a pharmaceutical agent for the complexation of iron. The pharmaceutical agent includes an initiator group, a polymer and a terminal group R7, and has the structure: initiator group-polymer-R7. The pharmaceutical agent further includes one or more functional hydroxamic acid groups of the type —(C?O)NHOH or —(C?O)NCH3OH.

Abstract: The present application is directed to a crosslinkable copolymer comprising styrene and 4-vinyl benzocyclobutene monomers and at least one alkoxysilane group, a method for generating an ultrathin copolymer film, which contains at least one crosslinked copolymer as defined herein, on a silicon-containing substrate, a composition or film comprising at least one copolymer as defined herein, as well as the use of this copolymer or composition containing it for electrical insulation and/or bonding of silicon-containing substrates.

Abstract: The synthesis of nanoparticles based on hyperbranched-linear-hyperbranched ABA triblock copolymers with hyperbranched polyglycerol (hbPG) as A-block and linear poly(oxymethylene) as B-block is described. The acid-degradable nanoparticles were formed in a facile process, combining a solvent evaporation process with the miniemulsion technique resulting in particles with a diameter in the range of 190 to 250 nm and a standard deviation of ˜30% determined with DLS and SEM. The nanoparticles were placed on a silicon wafer and sintered leading to films with a thickness in the ?m-range investigated via SEM. The surface properties of these films were investigated via static contact angle measurements at the liquid/vapor interface. The contact angle decreases from 67° for the polymer with two hydroxyl groups to 29° for the polymer with 16 hydroxyl groups, confirming the influence of the polymer structure and size of the hbPG block on the surface properties.

Abstract: Synthesis of hyperbranched-linear-hyperbranched ABA triblock copolymers based on linear poly(oxy methylene) (POM) and hyperbranched poly(glycerol) (hbPG) blocks is described. The polymers having a polyacetal polyether structure were prepared from linear bishydroxy functional POM macroinititators, obtained by cationic ring-opening polymerization of trioxane and dioxane with formic acid as transfer agent and following hydrolysis of the formiate group. Partial deprotonation of the resulting hydroxyl groups permitted the hypergrafting by anionic ring-opening multibranching polymerization (ROMBP) of glycidol.

Abstract: The invention relates to glycerol-modified polyorganosiloxane compounds with high hydrophilicity and their use.

Abstract: The present invention relates to a strategy for improving the permeability and solubility of pharmaceuticals, based on adding a chemically modified amino alkyl methacrylate copolymer E, wherein the chemical modification is the quaternization of a fraction of the existing amino alkyl groups.

Abstract: The invention relates to highly functional, aliphatic, branched polyethers produced from oxiranes, in particular ethylene oxide and glycidol or the sulfur- or nitrogen-containing analogues thereof. The branched polyethers are in particular suited as a matrix for pharmacological and cosmetic active agents.

Abstract: A novel polymeric initiator is disclosed comprising a dendritic polymer core with at least one initiating functional group as an end group. The dendritic polymeric core is preferably a hyperbranched polymer. The polymeric initiators are useful in radiation curable compositions such as varnishes, lacquers and printing inks and are especially useful in radiation curable inkjet inks.

Abstract: The present invention relates to a strategy for improving the permeability and solubility of pharmaceuticals, based on adding a chemically modified amino alkyl methacrylate copolymer E, wherein the chemical modification is the quaternization of a fraction of the existing amino alkyl groups.

Abstract: A novel polymeric initiator is disclosed comprising a dendritic polymer core with at least one initiating functional group as an end group. The dendritic polymeric core is preferably a hyperbranched polymer. The polymeric initiators are useful in radiation curable compositions such as varnishes, lacquers and printing inks and are especially useful in radiation curable inkjet inks.