Patents by Inventor Holger Hösch

Holger Hösch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9670166
    Abstract: This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: June 6, 2017
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christian Gnamm, Thorsten Oost, Stefan Peters, Holger Hoesch, Uwe Joerg Ries
  • Patent number: 9657015
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase activity and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: May 23, 2017
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christian Gnamm, Ralf Anderskewitz, Holger Hoesch, Gerd Morschhaeuser, Thorsten Oost, Stefan Peters, Uwe Joerg Ries
  • Publication number: 20160340319
    Abstract: This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.
    Type: Application
    Filed: August 5, 2016
    Publication date: November 24, 2016
    Inventors: Christian GNAMM, Thorsten OOST, Stefan PETERS, Holger HOESCH, Uwe Joerg RIES
  • Patent number: 9475779
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: October 25, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thorsten Oost, Ralf Anderskewitz, Christian Gnamm, Holger Hoesch, Gerd Morschhaeuser, Stefan Peters, Uwe Joerg Ries
  • Patent number: 9458113
    Abstract: Substituted dihydropyrimidinones of formula 1 which are neutrophil elastase inhibitors and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: October 4, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stefan Peters, Ralf Anderskewitz, Christian Gnamm, Holger Hoesch, Gerd Morschhaeuser, Thorsten Oost, Uwe Joerg Ries
  • Patent number: 9290459
    Abstract: This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: March 22, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christian Gnamm, Thorsten Oost, Stefan Peters, Holger Hoesch, Uwe Joerg Ries
  • Publication number: 20160060231
    Abstract: This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Inventors: Christian GNAMM, Thorsten OOST, Stefan PETERS, Holger HOESCH, Uwe Joerg REIS
  • Publication number: 20160060230
    Abstract: This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Inventors: Christian GNAMM, Thorsten OOST, Stefan PETERS, Holger HOESCH, Uwe Joerg REIS
  • Publication number: 20160039812
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase activity and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 11, 2016
    Inventors: Christian GNAMM, Ralf ANDERSKEWITZ, Holger HOESCH, Gerd MORSCHHAEUSER, Thorsten OOST, Stefan PETERS, Uwe Joerg RIES
  • Publication number: 20160031830
    Abstract: Substituted dihydropyrimidinones of formula 1 which are neutrophil elastase inhibitors and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Inventors: Stefan PETERS, Ralf ANDERSKEWITZ, Christian GNAMM, Holger HOESCH, Gerd MORSCHHAEUSER, Thorsten OOST, Uwe Joerg RIES
  • Publication number: 20160031829
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Inventors: Thorsten OOST, Ralf ANDERSKEWITZ, Christian GNAMM, Holger HOESCH, Gerd MORSCHHAEUSER, Stefan PETERS, Uwe Joerg RIES
  • Patent number: 6750317
    Abstract: Polyhydroxyamides are polymerized to form highly-crosslinked, temperature-stable polymers. The polyhydroxyamides include as their central, parent structure a benzenetricarboxylic acid to which side chains containing a terminal reactive group are attached by an amide bond. By way of this reactive group, highly crosslinked polymers can be formed. In addition, the polyhydroxyamide can be added as an additive to polymers in order to bring about three-dimensional crosslinking.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: June 15, 2004
    Assignee: Infineon Technologies AG
    Inventors: Marcus Halik, Holger Hösch, Sezi Recai, Andreas Walter