Patents by Inventor Holger Klein

Holger Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12013289
    Abstract: A device for measuring the temperature in the interior of a vehicle is provided. The device includes an interior temperature sensor arranged at and/or in a plug-in end of a plug-in housing. The interior temperature sensor projects beyond the plug-in end of the plug-in housing. The plug-in housing is biased away from a cover element for assuming a defined plug-in position of the plug-in housing when the plug-in end of the plug-in housing is plugged into a receiving space of the latter and the interior temperature sensor is arranged in the through-going opening of the cover element.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: June 18, 2024
    Assignee: BEHR-HELLA THERMOCONTROL GMBH
    Inventor: Holger Kleine-Hollenhorst
  • Publication number: 20240011033
    Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.
    Type: Application
    Filed: November 4, 2021
    Publication date: January 11, 2024
    Inventors: Sebastian Kreuz, Ludger Ickenstein, Marc Kaestle, Stephan Klee, Holger Klein, Thorsten Lamla, Benjamin Strobel
  • Publication number: 20230416738
    Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF #1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF #1-induced lung fibrosis model.
    Type: Application
    Filed: November 4, 2020
    Publication date: December 28, 2023
    Inventors: Sebastian Kreuz, Holger Klein, Benjamin Strobel, Stephan Klee, Thorsten Lamla, Marc Kaestle, Ludger Ickenstein
  • Publication number: 20230407303
    Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.
    Type: Application
    Filed: November 4, 2021
    Publication date: December 21, 2023
    Inventors: Sebastian Kreuz, Holger Klein, Benjamin Strobel, Stephan Klee, Thorsten Lamla, Marc Kaestle, Ludger Ickenstein
  • Patent number: 11756753
    Abstract: The operating device for a vehicle is provided with a housing having a front wall. At least one operating element is arranged on the front wall and can be manually actuated starting from a rest position for the purpose of entering a command or activating a function. The operating element is associated with a switch having a switching member on which the operating key acts during manual operation. Furthermore, a support element is arranged in the housing at a distance from the operating element, on which support element the switch associated with the operating element is arranged, the support element having a bending bar with an upper side facing the operating element and a lower side facing away from the upper side, and the switch being arranged on the bending bar.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: September 12, 2023
    Assignee: BEHR-HELLA THERMOCONTROL GMBH
    Inventors: Holger Kleine-Hollenhorst, Michael Arens
  • Publication number: 20220213503
    Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.
    Type: Application
    Filed: April 30, 2020
    Publication date: July 7, 2022
    Inventors: Sebastian Kreuz, Holger Klein, Benjamin Strobel, Stephan Klee, Thorsten Lamla, Marc Kaestle
  • Patent number: 9722705
    Abstract: An apparatus for controlling, monitoring, and communicating with an optical device, photonic integrated circuit or subassembly is provided. The apparatus includes an optical device or subassembly; and afield programmable device including programmable hardware gates coupled to the optical device or subassembly. The field programmable device may be configured to implement a plurality of functions at a gate level for controlling, monitoring, and/or communicating with the optical device or subassembly, each of the plurality of functions being configured to execute as a concurrent process, without use of a microprocessor or a microcontroller. Further, a programmable optical device, such as a programmable optical transmitter, optical subassembly, or transceiver based on a tunable laser having field programmable device centric control systems with software-enabled features offer extensive real-time control and monitoring functionality based on for example actual traffic flows.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: August 1, 2017
    Assignee: OE SOLUTIONS AMERICA, INC.
    Inventors: Daniel J. Blumenthal, Holger Klein, Todd Cicchi, Patrick Bybee, Henrik Poulsen
  • Patent number: 9614522
    Abstract: The operating device, such as a human-machine interface, in particular for a vehicle component, is provided with a front wall having a front side that has several fixed symbol fields and having a rear side, a capacitive sensor system that has individual electrodes associated with the symbol fields, which electrodes are arranged on the rear side of the front wall, and a carrier plate that faces the rear side of the front wall and is arranged at a distance from the front wall.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: April 4, 2017
    Assignee: Behr-Hella Thermocontrol GmbH
    Inventors: Holger Kleine-Hollenhorst, Bernd Stich, Rainer Siebert
  • Patent number: 9543737
    Abstract: A method and apparatus for calibrating and controlling tunable lasers are disclosed. Multiple methodologies disclosed herein may be used, alone or in combination, which significantly speed up a calibration time and thus provide a significant advantage over existing technology in calibrating the tunable lasers. Certain methodologies benefit from a unique design of the tunable lasers that couple two or more optical facets to an output. The tunable lasers may be equipped with two or more sampled grating distributed Bragg reflector (SGDBR) mirrors and may include Semiconductor Optical Amplifiers (SOAs) after the SGDBR mirrors.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: January 10, 2017
    Assignee: OE SOLUTIONS AMERICA, INC.
    Inventors: Daniel Blumenthal, Holger Klein, Chad Althouse, Todd Chicci, Patrick Bybee, Henrik Poulsen, Sarat Chandra Gundavarapu
  • Publication number: 20160291269
    Abstract: A localized hermetic sealing of a photonic integrated circuit component chip mounted in a photonic integrated circuit device chip to protect a chip-to-chip interface from contamination, thereby enhancing functionality and reliability. A covering lid mounted on or over the component chip is hermetically sealed to the device chip surrounding the component chip forming a localized hermetically sealed area.
    Type: Application
    Filed: September 28, 2015
    Publication date: October 6, 2016
    Inventors: Holger Klein, Michael J. Hochberg, Nathan A. Nuttall
  • Publication number: 20160254644
    Abstract: A method and apparatus for calibrating and controlling tunable lasers are disclosed. Multiple methodologies disclosed herein may be used, alone or in combination, which significantly speed up a calibration time and thus provide a significant advantage over existing technology in calibrating the tunable lasers. Certain methodologies benefit from a unique design of the tunable lasers that couple two or more optical facets to an output. The tunable lasers may be equipped with two or more sampled grating distributed Bragg reflector (SGDBR) mirrors and may include Semiconductor Optical Amplifiers (SOAs) after the SGDBR mirrors.
    Type: Application
    Filed: October 30, 2015
    Publication date: September 1, 2016
    Inventors: Daniel Blumenthal, Holger Klein, Chad Althouse, Todd Chicci, Patrick Bybee, Henrik Poulsen, Sarat Chandra Gundavarapu
  • Publication number: 20160254866
    Abstract: An apparatus for controlling, monitoring, and communicating with an optical device, photonic integrated circuit or subassembly is provided. The apparatus includes an optical device or subassembly; and afield programmable device including programmable hardware gates coupled to the optical device or subassembly. The field programmable device may be configured to implement a plurality of functions at a gate level for controlling, monitoring, and/or communicating with the optical device or subassembly, each of the plurality of functions being configured to execute as a concurrent process, without use of a microprocessor or a microcontroller. Further, a programmable optical device, such as a programmable optical transmitter, optical subassembly, or transceiver based on a tunable laser having field programmable device centric control systems with software-enabled features offer extensive real-time control and monitoring functionality based on for example actual traffic flows.
    Type: Application
    Filed: November 20, 2015
    Publication date: September 1, 2016
    Inventors: Daniel J. Blumenthal, Holger Klein, Todd Cicchi, Patrick Bybee, Henrik Poulsen
  • Patent number: 9257243
    Abstract: The operating device (10), in particular for a vehicle component or generally for a human/machine interface, is provided with at least one pushbutton (28), which has a depressible pushbutton element (26). In addition, the operating device (10) has a guide element (18), which defines an accommodating area (24) in which the pushbutton element (26) is at least partially accommodated and in which the pushbutton element (26) is guided, and a capacitive proximity sensor (36) with an electrode (34) for detecting an object approaching the pushbutton element (26), in particular a hand or a finger of a hand. The electrode (34) is arranged outside the accommodating area (24) of the guide element (18).
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: February 9, 2016
    Assignee: Behr-Hella Thermocontrol GMBH
    Inventors: Rainer Siebert, Bernd Stich, Holger Kleine-Hollenhorst
  • Patent number: 9090141
    Abstract: A vehicle wheel suspension is provided having a hydraulic vibration damper, which is connected in parallel to a suspension spring which proportionally supports the vehicle body. A rebound spring is provided, which preferably and typically becomes effective in the event of larger spring deflection distances. The support point of the rebound spring is displaceable in relation to the damper housing by way of a spring support piston, which is provided therein and is displaceable by fluid externally supplied with pressure via pump. In this case, the pump is connected to a pressure accumulator for the fluid and delivers fluid out of the pressure accumulator into the damper housing or out of the damper housing back into the pressure accumulator. The absolute value of the spring constant of the pressure accumulator is at least in the order of magnitude of the spring constant of the associated suspension spring or springs, or is greater.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: July 28, 2015
    Assignee: Bayerische Motoren Werke Aktiengesellschaft
    Inventors: Roland Schmidt, Serge Vos, Holger Klein
  • Publication number: 20140347301
    Abstract: The operating device, such as a human-machine interface, in particular for a vehicle component, is provided with a front wall having a front side that has several fixed symbol fields and having a rear side, a capacitive sensor system that has individual electrodes associated with the symbol fields, which electrodes are arranged on the rear side of the front wall, and a carrier plate that faces the rear side of the front wall and is arranged at a distance from the front wall.
    Type: Application
    Filed: September 18, 2012
    Publication date: November 27, 2014
    Inventors: Holger Kleine-Hollenhorst, Bernd Stich, Rainer Siebert
  • Publication number: 20140217693
    Abstract: A vehicle wheel suspension is provided having a hydraulic vibration damper, which is connected in parallel to a suspension spring which proportionally supports the vehicle body. A rebound spring is provided, which preferably and typically becomes effective in the event of larger spring deflection distances. The support point of the rebound spring is displaceable in relation to the damper housing by way of a spring support piston, which is provided therein and is displaceable by fluid externally supplied with pressure via pump. In this case, the pump is connected to a pressure accumulator for the fluid and delivers fluid out of the pressure accumulator into the damper housing or out of the damper housing back into the pressure accumulator. The absolute value of the spring constant of the pressure accumulator is at least in the order of magnitude of the spring constant of the associated suspension spring or springs, or is greater.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: Bayerische Motoren Werke Aktiengesellschaft
    Inventors: Roland SCHMIDT, Serge VOS, Holger KLEIN
  • Publication number: 20140124350
    Abstract: The operating device (10), in particular for a vehicle component or generally for a human/machine interface, is provided with at least one pushbutton (28), which has a depressible pushbutton element (26). In addition, the operating device (10) has a guide element (18), which defines an accommodating area (24) in which the pushbutton element (26) is at least partially accommodated and in which the pushbutton element (26) is guided, and a capacitive proximity sensor (36) with an electrode (34) for detecting an object approaching the pushbutton element (26), in particular a hand or a finger of a hand. The electrode (34) is arranged outside the accommodating area (24) of the guide element (18).
    Type: Application
    Filed: April 17, 2012
    Publication date: May 8, 2014
    Inventors: Rainer Siebert, Bernd Stich, Holger Kleine-Hollenhorst
  • Patent number: 7541506
    Abstract: The invention relates to a process for the telomerization of acyclic olefins having at least two conjugated double bonds (I) or mixtures in which such olefins are present with nucleophiles (II) using a metal-carbene complex as catalyst.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: June 2, 2009
    Assignee: OXENO Olefinchemie GmbH
    Inventors: Dirk Roettger, Ralf Jackstell, Holger Klein, Matthias Beller
  • Patent number: 7371909
    Abstract: The invention relates to a process 1-olefins by telomerization of compounds having conjugated double bonds with a telogen in the presence of a noble metal telomerization catalyst, hydrogenation of the telomer and cleavage of the hydrogenated intermediate. Use of the 1-olefin as comonomer.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: May 13, 2008
    Assignee: Oxeno Olefinchemie GmbH
    Inventors: Matthias Beller, Ralf Jackstell, Holger Klein, Dirk Roettger, Klaus-Diether Wiese, Dietrich Maschmeyer, Axel Tuchlenski, Alfred Kaizik, Silvia Santiago Fernandez
  • Patent number: 7115790
    Abstract: The invention relates to a process for preparing 1-octene by telomerization of 1,3-butadiene using a reducing agent in the presence of a telomerization catalyst and partial hydrogenation of the octadiene obtained in this way.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: October 3, 2006
    Assignee: OXENO Olefinchemie GmbH
    Inventors: Matthias Beller, Ralf Jackstell, Holger Klein, Dirk Roettger, Dietrich Maschmeyer, Silvia Santiago Fernandez