Patents by Inventor Holger Metzner
Holger Metzner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8557511Abstract: A method and an apparatus are described for infiltrating tissue samples with carrier material, preferably paraffin. A supply of carrier material is kept ready for use in a supply station. From there, the carrier material can be delivered into at least a first and a second container. In these first and second containers carrier materials of differing degrees of purity are kept ready for use, respectively, for performing various infiltration steps on tissue samples. By means of the described method and apparatus the tissue processor can be operated with as little interruptions as possible and an ease in operation is achieved.Type: GrantFiled: August 17, 2009Date of Patent: October 15, 2013Assignee: Leica Instruments (Singapore) Pte. Ltd.Inventors: Hermann Ulbrich, Michael Rapp, Marc Konrad, Holger Metzner, Markus Dobusch, Eva Goedecke, Stefan Kuenkel, Udo Herrmann
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Patent number: 8288086Abstract: A method for operating a tissue processor and a respective tissue processor for performing this method are described for the processing tissue samples. The tissue processor comprises at least one retort for receiving the tissue samples and at least one container for receiving a process medium. The process medium is transferred at least one of from the container into the retort and from the retort into the container. A value is automatically measured in the course of transferring the process medium, the value representing a characteristic property of the process medium. The process medium is identified based on the value.Type: GrantFiled: October 27, 2009Date of Patent: October 16, 2012Assignee: Leica Biosystems Nussloch GmbHInventors: Holger Metzner, Udo Herrmann, Hermann Ulbrich, Eva Goedecke
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Patent number: 8039262Abstract: A method for controlling a tissue processor and a tissue processor for processing tissue samples is described. A retort is provided including a cover that can be opened and closed by an operator. The retort cover is closed prior to tissue processing. The actuation state of a first and a second operating element can be determined. An operator is prompted to confirm unlocking of the closed retort cover by actuating a second operating element. The tissue processing is interrupted when an actuation of the second operating element is determined and the closed retort cover is unlocked and is continued after the retort cover is once again locked. After having completed tissue processing the retort cover is unlocked. By means of the described method and tissue processor improper intervention during ongoing tissue processing is prevented.Type: GrantFiled: August 21, 2009Date of Patent: October 18, 2011Assignee: Leica Biosystems Nussloch GmbHInventors: Marc Konrad, Holger Metzner, Udo Hermann, Frank Meder, Hermann Ulbrich, Markus Dobusch, Stefan Künkel
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Patent number: 7722811Abstract: A tissue processor (1) is described, having a retort (2) for processing histological samples with different reagents, having multiple reagent reservoir vessels (3), and having a conduit system and a control device (5) for delivering reagents out of the reagent reservoir vessels (3) into the retort (2). A suction conduit (11) projects into each reagent reservoir vessel (3) through the vessel opening (7) for reagent withdrawal. A closure system (12) having an externally tapered and internally hollow closure plug (13) is provided for closing off the vessel opening (7). The suction conduit (11) is guided through a cavity (14) of the closure plug (13) for reagent withdrawal.Type: GrantFiled: November 22, 2006Date of Patent: May 25, 2010Assignee: Leica Biosystems Nussloch GmbHInventors: Marc Konrad, Stefan Künkel, Holger Metzner, Eberhard Sendobry, Markus Dobusch
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Publication number: 20100112624Abstract: A method for operating a tissue processor and a respective tissue processor for performing this method are described for the processing tissue samples. The tissue processor comprises at least one retort for receiving the tissue samples and at least one container for receiving a process medium. The process medium is transferred at least one of from the container into the retort and from the retort into the container. A value is automatically measured in the course of transferring the process medium, the value representing a characteristic property of the process medium. The process medium is identified based on the value.Type: ApplicationFiled: October 27, 2009Publication date: May 6, 2010Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Holger Metzner, Udo Herrmann, Hermann Ulbrich, Eva Goedecke
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Publication number: 20100055663Abstract: A method for controlling a tissue processor and a tissue processor for processing tissue samples is described. A retort is provided comprising a cover that can be opened and closed by an operator. The retort cover is closed prior to tissue processing. The actuation state of a first and a second operating element can be determined. An operator is prompted to confirm unlocking of the closed retort cover by actuating a second operating element. The tissue processing is interrupted when an actuation of the second operating element is determined and the closed retort cover is unlocked and is continued after the retort cover is once again locked. After having completed tissue processing the retort cover is unlocked. By means of the described method and tissue processor improper intervention during ongoing tissue processing is prevented.Type: ApplicationFiled: August 21, 2009Publication date: March 4, 2010Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Marc Konrad, Holger Metzner, Udo Hermann, Frank Meder, Hermann Ulbrich, Markus Dobusch, Stefan Künkel
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Publication number: 20100055788Abstract: A method and an apparatus are described for infiltrating tissue samples with carrier material, preferably paraffin. A supply of carrier material is kept ready for use in a supply station. From there, the carrier material can be delivered into at least a first and a second container. In these first and second containers carrier materials of differing degrees of purity are kept ready for use, respectively, for performing various infiltration steps on tissue samples. By means of the described method and apparatus the tissue processor can be operated with as little interruptions as possible and an ease in operation is achieved.Type: ApplicationFiled: August 17, 2009Publication date: March 4, 2010Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBHInventors: Hermann Ulbrich, Michael Rapp, Marc Konrad, Holger Metzner, Markus Dobusch, Eve Goedecke, Stefan Kuenkel, Udo Herrmann
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Patent number: 7449147Abstract: An apparatus for collecting imprinted cassettes and/or specimen slides for histological or cytological preparations comprises a motor-driven lifting platform (1) having panels (2) arranged one above another and adjustable as to height by way of the lifting platform (1), for collection of the cassettes and/or specimen slides.Type: GrantFiled: May 12, 2003Date of Patent: November 11, 2008Assignee: Leica Biosystems Nussloch GmbHInventors: Holger Metzner, Uwe Kiene, Manfred Biehl
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Publication number: 20070122910Abstract: A tissue processor (1) is described, having a retort (2) for processing histological samples with different reagents, having multiple reagent reservoir vessels (3), and having a conduit system and a control device (5) for delivering reagents out of the reagent reservoir vessels (3) into the retort (2). A suction conduit (11) projects into each reagent reservoir vessel (3) through the vessel opening (7) for reagent withdrawal. A closure system (12) having an externally tapered and internally hollow closure plug (13) is provided for closing off the vessel opening (7). The suction conduit (11) is guided through a cavity (14) of the closure plug (13) for reagent withdrawal.Type: ApplicationFiled: November 22, 2006Publication date: May 31, 2007Inventors: Marc Konrad, Stefan Kunkel, Holger Metzner, Eberhard Sendobry, Markus Dobusch
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Patent number: 6899228Abstract: A panel (1) for receiving cassettes (2) and/or specimen slides (3) for histological or cytological preparations is embodied in rectangular fashion with two longitudinal sides (4), a first narrow side (5) and a second narrow side (6), and comprises a base (7) as support for the specimen slides (3) and/or cassettes (2). Peripheral side walls (8) are provided on both longitudinal sides (4) and on the first narrow side (5).Type: GrantFiled: May 21, 2003Date of Patent: May 31, 2005Assignee: Leica Microsystems Nussloch GmbHInventors: Uwe Kiene, Manfred Biehl, Holger Metzner
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Patent number: 6814257Abstract: A delivery device (5) for cassettes and/or specimen slides for histological preparations in a printing system (11) is described. The cassettes and/or specimen slides are in each case arranged one above another in stack magazines (6), a control device (1) being provided for removal of a cassette and/or specimen slide from the stack magazines (6). The improvement comprises a drive shaft (12) having a motor (13) for at least two stack magazines (6), and the motor (13) is connected to the control device (1).Type: GrantFiled: July 30, 2002Date of Patent: November 9, 2004Assignee: Leica Microsystems Nussloch GmbHInventors: Uwe Kiene, Andreas Laudat, Holger Metzner, Manfred Biehl, Roland Walter, Bernd Guenther
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Patent number: 6766593Abstract: An apparatus (1) for drying solvent-based ink is described, in which the ink is applied onto plastic cassettes for histological preparations and/or on glass specimen slides (17) for microscopic thin sections. The apparatus (1) comprises a hot-air blower (2) and/or a flash device (3) for drying the ink.Type: GrantFiled: March 22, 2002Date of Patent: July 27, 2004Assignee: Leica Microsystems Nussloch GmbHInventors: Andreas Laudat, Holger Metzner, Roland Walter
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Patent number: 6715870Abstract: A method and an apparatus for printing onto plastic cassettes for histological preparations and/or onto glass specimen slides for microscopic thin sections are described, in which a computing device (1) is provided to control the printing device (2), and the printing device (2) comprises an inkjet printer for printing onto the cassettes and/or specimen slides. The ink is pre-dried by way of a hot-air drier (3) and completely dried by way of a flash device (4).Type: GrantFiled: March 26, 2002Date of Patent: April 6, 2004Assignee: Leica Microsystems Nussloch GmbHInventors: Uwe Kiene, Manfred Biehl, Andreas Laudat, Holger Metzner, Rolf Metzner, Roland Walter
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Publication number: 20030217945Abstract: A panel (1) for receiving cassettes (2) and/or specimen slides (3) for histological or cytological preparations is embodied in rectangular fashion with two longitudinal sides (4), a first narrow side (5) and a second narrow side (6), and comprises a base (7) as support for the specimen slides (3) and/or cassettes (2). Peripheral side walls (8) are provided on both longitudinal sides (4) and on the first narrow side (5).Type: ApplicationFiled: May 21, 2003Publication date: November 27, 2003Inventors: Uwe Kiene, Manfred Biehl, Holger Metzner
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Publication number: 20030215363Abstract: An apparatus for collecting imprinted cassettes and/or specimen slides for histological or cytological preparations comprises a motor-driven lifting platform (1) having panels (2) arranged one above another and adjustable as to height by way of the lifting platform (1), for collection of the cassettes and/or specimen slides.Type: ApplicationFiled: May 12, 2003Publication date: November 20, 2003Inventors: Holger Metzner, Uwe Kiene, Manfred Biehl
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Publication number: 20030059281Abstract: A delivery device (5) for cassettes and/or specimen slides for histological preparations in a printing system (11) is described. The cassettes and/or specimen slides are in each case arranged one above another in stack magazines (6), a control device (1) being provided for removal of a cassette and/or specimen slide from the stack magazines (6). The improvement comprises a drive shaft (12) having a motor (13) for at least two stack magazines (6), and the motor (13) is connected to the control device (1).Type: ApplicationFiled: July 30, 2002Publication date: March 27, 2003Inventors: Uwe Kiene, Andreas Laudat, Holger Metzner, Manfred Biehl, Roland Walter, Bernd Guenther
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Publication number: 20030049178Abstract: An apparatus for imprinting cassettes (1) and/or specimen slides, having a printing head (2) and a delivery device (3) for the cassettes (1) and/or specimen slides, is described. A pivot device (5) is provided for alignment of the printing head (2) with differently inclined printing planes (4) or for alignment of differently inclined printing planes (4) with the printing head (2).Type: ApplicationFiled: July 26, 2002Publication date: March 13, 2003Inventors: Uwe Kiene, Andreas Laudat, Holger Metzner, Roland Walter
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Publication number: 20020167577Abstract: A method and an apparatus for printing onto plastic cassettes for histological preparations and/or onto glass specimen slides for microscopic thin sections are described, in which a computing device (1) is provided to control the printing device (2), and the printing device (2) comprises an inkjet printer for printing onto the cassettes and/or specimen slides. The ink is pre-dried by way of a hot-air drier (3) and completely dried by way of a flash device (4).Type: ApplicationFiled: March 26, 2002Publication date: November 14, 2002Inventors: Uwe Kiene, Manfred Biehl, Andreas Laudat, Holger Metzner, Rolf Metzner, Roland Walter
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Publication number: 20020139004Abstract: An apparatus (1) for drying solvent-based ink is described, in which the ink is applied onto plastic cassettes for histological preparations and/or on glass specimen slides (17) for microscopic thin sections. The apparatus (1) comprises a hot-air blower (2) and/or a flash device (3) for drying the ink.Type: ApplicationFiled: March 22, 2002Publication date: October 3, 2002Inventors: Andreas Laudat, Holger Metzner, Roland Walter