Patents by Inventor Holger Zimmermann

Holger Zimmermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220401553
    Abstract: The present invention relates to the treatment of coronavirus infections and to preparing subjects for such an infection by administering a parapoxvirus. This treatment is to assist the immune system in combatting the virus and to thereby prevent and to ameliorate symptoms of coronavirus disease.
    Type: Application
    Filed: May 10, 2021
    Publication date: December 22, 2022
    Inventors: Daniela Paulsen, Alexander Birkmann, Peter Lischka, Tamara Pfaff, Holger Zimmermann
  • Patent number: 10156196
    Abstract: A reciprocating internal combustion engine with an emission control device and a method for operating same are described. At least one throttle, arranged on the intake side, at least one main fuel injection nozzle for feeding a main fuel to a combustion chamber of the diesel engine, and at least one catalytic converter are arranged in the center of an exhaust gas passage for conducting exhaust gas out of the combustion chamber, and at least one control device is used. A soot burn-off rate determined according to a model approach is maximized using a regulation process by means of a throttle valve.
    Type: Grant
    Filed: November 2, 2013
    Date of Patent: December 18, 2018
    Assignee: DEUTZ Aktiengesellschaft
    Inventors: Sven Jerzembeck, Abderrahim Qriqra, Holger Zimmermann, Peter Heidkamp
  • Publication number: 20150292426
    Abstract: A reciprocating internal combustion engine with an emission control device and a method for operating same are described. At least one throttle, arranged on the intake side, at least one main fuel injection nozzle for feeding a main fuel to a combustion chamber of the diesel engine, and at least one catalytic converter are arranged in the centre of an exhaust gas passage for conducting exhaust gas out of the combustion chamber, and at least one control device is used. A soot burn-off rate determined according to a model approach is maximized using a regulation process by means of a throttle valve.
    Type: Application
    Filed: November 2, 2013
    Publication date: October 15, 2015
    Inventors: Sven Jerzembeck, Abderrahim Qriqra, Holger Zimmermann, Peter Heidkamp
  • Patent number: 8513255
    Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: August 20, 2013
    Assignee: AiCuris GmbH + Co. KG.
    Inventors: Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Thomas Lampe, Susanne Nikolic, Juergen Reefschlaeger, Rudolf Schohe-Loop, Frank Suessmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Joerg Keldenich, Dieter Lang, Peter Nell
  • Patent number: 8410090
    Abstract: The invention relates to heterocyclylamide-substituted thiazoles, pyrroles and thiophenes and processes for their preparation, to pharmaceutical compositions containing them, and to their use for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: July 1, 2006
    Date of Patent: April 2, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Holger Zimmermann, David Brueckner, Kerstin Henninger, Martin Hendrix, Martin Radtke
  • Patent number: 8349820
    Abstract: The invention relates to the use, optionally together with oral contraception, of estradiol valerate or 17?-estradiol in combination with 17?-cyanomethyl-17-?-hydroxyestra-4,9-dien-3-one (dienogest) in a multistage or single-stage combination preparation for oral therapy to maintain and/or increase feminine libido. The total number of daily dose units of the multistage combination and of a pharmaceutically harmless placebo or a single-stage combination and optionally the pharmaceutically harmless placebo-containing or placebo- and hormone-free daily dose units amounts to 28 daily dose units.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: January 8, 2013
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Susan Zeun, Holger Zimmermann, Susanne Parke
  • Patent number: 8343981
    Abstract: The invention relates to heterocyclyl-substituted dihydroquinazolines of formula (I), to processes for their preparation, to medicaments containing them, and to methods for the treatment and/or prophylaxis of diseases, in particular, for use as anti-viral agents, in particular, against cytomegaloviruses.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: January 1, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Tobias Wunberg, Judith Baumeister, Mario Jeske, Peter Nell, Susanne Nikolic, Frank Suessmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Joerg Keldenich, Dieter Lang
  • Patent number: 8318761
    Abstract: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: November 27, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Niels Svenstrup, Holger Zimmermann, Dagmar Karthaus, Andreas Goeller, Dirk Heimbach, Kerstin Henninger, Dieter Lang, Daniela Paulsen, Bernd Riedl, Rudolf Schohe-Loop, Joachim Schuhmacher, Tobias Wunberg
  • Patent number: 8314113
    Abstract: The invention relates to substituted dihydroquinazolines and to a method for the production thereof, the use thereof for treating and/or preventing diseases and for producing drugs for treating and/or preventing diseases, in particular for the use of the inventive dihydroquinazolines in the form of antiviral agents, in particular against cytomegaloviruses.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: November 20, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Tobias Wunberg, Judith Baumeister, Mario Jeske, Peter Nell, Susanne Nikolic, Frank Suessmeier, Holger Zimmermann, Rolf Grosser, Guy Hewlett, Jorg Keldenich, Dieter Lang, Kerstin Henninger
  • Patent number: 8198282
    Abstract: This invention relates to substituted azaquinazolines, to a process for their preparation, to pharmaceutical compositions containing them, and to their use for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particular against cytomegaloviruses.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: June 12, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Tobias Wunberg, Judith Baumeister, Mario Jeske, Frank Suessmeier, Holger Zimmermann, Kerstin Henninger, Dieter Lang
  • Patent number: 8153616
    Abstract: The multiphase combination preparation for oral therapy of dysfunctional uterine bleeding and for oral contraception contains a first phase consisting of 2 daily dosage units, each containing 3 mg of estradiol valerate or <3 mg of estradiol; a second phase consisting of a first group of 5 daily dosage units, each consisting of a combination of 2 mg of dienogest with 2 mg of estradiol valerate or <2 mg of estradiol, and a second group consisting of 17 daily dosage units, each consisting of a combination of 3 mg of dienogest with 2 mg of estradiol valerate or <2 mg of estradiol; a third phase consisting of 2 daily dosage units, each containing 1 mg of estradiol valerate or <1 mg of estradiol; and another phase consisting of 2 daily dosage units of a pharmaceutically harmless placebos.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: April 10, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Susan Zeun, Pol Boudes, Angelo Secci, Jan Nedrikat, Holger Zimmermann
  • Patent number: 7977349
    Abstract: The invention relates to substituted quinolones and to methods for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: July 12, 2011
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Chantal Fuerstner, Kai Thede, Holger Zimmermann, David Brueckner, Kerstin Henninger, Dieter Lang, Rudolf Schohe-Loop
  • Patent number: 7960387
    Abstract: The invention relates to dihydroquinazolines and methods for the production thereof, the use thereof in the treatment and/or prophylaxis of diseases, in addition to the use thereof in the production of medicaments in the treatment and/or prophylaxis of diseases, especially for use as anti-viral agents, especially against cytomegalo viruses.
    Type: Grant
    Filed: January 29, 2004
    Date of Patent: June 14, 2011
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Gerald Kleymann, Thomas Lampe, Susanne Nikolic, Jürgen Reefschläger, Rudolf Schohe-Loop, Frank Süβmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jörg Keldenich, Thomas Krämer, Peter Nell, Tse-I Lin
  • Patent number: 7919489
    Abstract: The invention relates to heterocyclylamide-substituted imidazoles and methods for their preparation, their use for the treatment and/or prophylaxis of diseases as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: April 5, 2011
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Holger Zimmermann, David Brueckner, Kerstin Henninger, Ulrich Rosentreter, Martin Hendrix, Joerg Keldenich, Dieter Lang, Martin Radtke, Daniela Paulsen, Armin Kern
  • Publication number: 20110008409
    Abstract: The pharmaceutical preparation for treating endometriosis contains at least 28, preferably 30, daily dose units, each of which contain dienogest, cyproterone acetate, or chlormadinone acetate at a daily dose that is at most twice that required to inhibit ovulation together with one or more pharmaceutical aids and/or carriers. The daily dose units are administered in a method of prophylaxis and/or therapy of endometriosis continuously during a time interval of at least 169 days or 25 weeks, preferably more than two years. The method effectively reduces endometriosis and associated pain, while undesirable side effects including bone density decrease are reduced or eliminated.
    Type: Application
    Filed: September 20, 2010
    Publication date: January 13, 2011
    Applicant: Bayer Schering Pharma AG
    Inventors: Christian Seitz, Annemarie Wasserfall, Holger Zimmermann
  • Patent number: 7867992
    Abstract: The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
    Type: Grant
    Filed: January 19, 2007
    Date of Patent: January 11, 2011
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Holger Zimmermann, Rudolf Schohe-Loop, Kerstin Henninger, Dieter Lang, Kai Thede, Chantal Fuerstner, David Brueckner, Daniela Paulsen, Thomas Roelle, Johannes Koebberling, Marcus Bauser
  • Patent number: 7767704
    Abstract: The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: August 3, 2010
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Holger Zimmermann, David Brueckner, Dirk Heimbach, Martin Hendrix, Kerstin Henninger, Guy Hewlett, Ulrich Rosentreter, Joerg Keldenich, Dieter Lang, Martin Radtke
  • Publication number: 20100190757
    Abstract: The multiphase combination preparation for oral therapy of dysfunctional uterine bleeding and for oral contraception contains a first phase consisting of 2 daily dosage units, each containing 3 mg of estradiol valerate or <3 mg of estradiol; a second phase consisting of a first group of 5 daily dosage units, each consisting of a combination of 2 mg of dienogest with 2 mg of estradiol valerate or <2 mg of estradiol, and a second group consisting of 17 daily dosage units, each consisting of a combination of 3 mg of dienogest with 2 mg of estradiol valerate or <2 mg of estradiol; a third phase consisting of 2 daily dosage units, each containing 1 mg of estradiol valerate or <1 mg of estradiol; and another phase consisting of 2 daily dosage units of a pharmaceutically harmless placebos.
    Type: Application
    Filed: March 18, 2010
    Publication date: July 29, 2010
    Inventors: Susan Zeun, Pol Boudes, Angelo Secci, Jan Nedrikat, Holger Zimmermann
  • Patent number: RE46791
    Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: April 17, 2018
    Assignee: AICURIS ANTI-INFECTIVE CURES GMBH
    Inventors: Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Thomas Lampe, Susanne Nikolic, Jurgen Reefschlager, Rudolf Schohe-Loop, Frank Sussmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jorg Keldenich, Dieter Lang, Peter Nell
  • Patent number: RE49698
    Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: October 17, 2023
    Assignee: AIC246 AG & Co. KG
    Inventors: Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Thomas Lampe, Susanne Nikolic, Jurgen Reefschlager, Rudolf Schohe-Loop, Frank Sussmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jorg Keldenich, Dieter Lang, Peter Nell