Patents by Inventor Holly ATTON
Holly ATTON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260001869Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.Type: ApplicationFiled: April 30, 2025Publication date: January 1, 2026Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, Ian YULE, Adele FAULKNER, Holly ATTON, Alastair PARKES, Serge CONVERS-REIGNIER, Michelle SOUTHEY, David T. PUERTA
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Publication number: 20250188071Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra2, Ra4, Ra5, Ra6, Ra7, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.Type: ApplicationFiled: February 19, 2025Publication date: June 12, 2025Applicant: EVOTEC INTERNATIONAL GMBHInventors: Holly ATTON, Christopher John BROWN, James Lindsay CARR, Serge CONVERS-REIGNIER, Michael CORR, Marissa FLOWER, Christopher Francis PALMER, Irena REBOULE, Mohamad SABBAH, Scott SADLER, Jonathan SHINE, Daryl Simon WALTER
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Patent number: 12325699Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.Type: GrantFiled: June 9, 2022Date of Patent: June 10, 2025Assignee: BLACKSMITH MEDICINES, INC.Inventors: Min Teng, Baskar Nammalwar, Xiaoming Li, Christian Perez, Ian Yule, Adele Faulkner, Holly Atton, Alastair Parkes, Serge Convers-Reignier, Michelle Southey, David T. Puerta
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Patent number: 12258338Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra2, Ra4, Ra5, Ra6, Ra7, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.Type: GrantFiled: April 22, 2020Date of Patent: March 25, 2025Assignee: Evotec International GmbHInventors: Holly Atton, Christopher John Brown, James Lindsay Carr, Serge Convers-Reignier, Michael Corr, Marissa Flower, Christopher Francis Palmer, Irena Reboule, Mohamad Sabbah, Scott Sadler, Jonathan Shine, Daryl Simon Walter
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Patent number: 11897866Abstract: The present invention provides compounds useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders.Type: GrantFiled: November 9, 2021Date of Patent: February 13, 2024Assignee: Padlock Therapeutics, Inc.Inventors: Rajesh Devraj, Gnanasambandam Kumaravel, Holly Atton, Edward Beaumont, Elise Gadouleau, Laura Gleave, Philip Stephen Kerry, Cristina Lecci, Mirco Meniconi, Nat Monck, Jordan Palfrey, Kostas Papadopoulos, Heather Tye, Philip A. Woods
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Publication number: 20220324846Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.Type: ApplicationFiled: June 9, 2022Publication date: October 13, 2022Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, Ian YULE, Adele FAULKNER, Holly ATTON, Alastair PARKES, Serge CONVERS-REIGNIER, Michelle SOUTHEY, David T. PUERTA
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Patent number: 11407740Abstract: Provided herein are heterocyclic derivative compounds of Formula (II), and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.Type: GrantFiled: March 18, 2021Date of Patent: August 9, 2022Assignee: FORGE THERAPEUTICS, INC.Inventors: Min Teng, Baskar Nammalwar, Xiaoming Li, Christian Perez, Ian Yule, Adele Faulkner, Holly Atton, Alastair Parkes, Serge Convers-Reignier, Michelle Southey, David T. Puerta
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Publication number: 20220227747Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra2, Ra4, Ra5, Ra6, Ra7, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.Type: ApplicationFiled: April 22, 2020Publication date: July 21, 2022Inventors: Holly ATTON, Christopher John BROWN, James Lindsay CARR, Serge CONVERS-REIGNIER, Michael CORR, Marissa FLOWER, Christopher Francis PALMER, Irena REBOULE, Mohamad SABBAH, Scott SADLER, Jonathan SHINE, Daryl Simon WALTER
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Publication number: 20220081421Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.Type: ApplicationFiled: November 14, 2019Publication date: March 17, 2022Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Ian YULE, Alastair PARKES, Heather TYE, Holly ATTON, Helen WILLIAMS, Adele FAULKNER, Serge CONVERS-REIGNIER, David T. PUERTA
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Publication number: 20220081418Abstract: The present invention provides compounds useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders.Type: ApplicationFiled: November 9, 2021Publication date: March 17, 2022Inventors: Rajesh Devraj, Gnanasambandam Kumaravel, Holly Atton, Edward Beaumont, Elise Gadouleau, Laura Gleave, Philip Stephen Kerry, Cristina Lecci, Mirco Meniconi, Nat Monck, Jordan Palfrey, Kostas Papadopoulos, Heather Tye, Philip A. Woods
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Patent number: 11198681Abstract: The present invention provides compounds useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders.Type: GrantFiled: February 22, 2017Date of Patent: December 14, 2021Assignee: Padlock Therapeutics, Inc.Inventors: Rajesh Devraj, Gnanasambandam Kumaravel, Holly Atton, Edward Beaumont, Elise Gadouleau, Laura Gleave, Philip Stephen Kerry, Cristina Lecci, Mirco Meniconi, Nat Monck, Jordan Palfrey, Kostas Papadopoulos, Heather Tye, Philip A. Woods
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Publication number: 20210221796Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.Type: ApplicationFiled: March 18, 2021Publication date: July 22, 2021Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, Ian YULE, Adele FAULKNER, Holly ATTON, Alastair PARKES, Serge CONVERS-REIGNIER, Michelle SOUTHEY, David T. PUERTA
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Publication number: 20210188810Abstract: The present invention provides compounds useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders.Type: ApplicationFiled: February 22, 2017Publication date: June 24, 2021Inventors: Rajesh Devraj, Gnanasambandam Kumaravel, Holly Atton, Edward Beaumont, Elise Gadouleau, Laura Gleave, Philip Stephen Kerry, Cristina Lecci, Mirco Meniconi, Nat Monck, Jordan Palfrey, Kostas Papadopoulos, Heather Tye
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Publication number: 20200095236Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.Type: ApplicationFiled: May 9, 2018Publication date: March 26, 2020Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, Xiaoming LI, David T. PUERTA, Serge CONVERS-REIGNIER, Holly ATTON, Ian YULE, Heather TYE, Adele FAULKNER, Alastair PARKES
