Patents by Inventor Holly Basham

Holly Basham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
    Patent number: 9689047
    Abstract: Methods and materials for determining the presence of at least one nucleic acid in a sample are provided, said methods comprising (1) a purification step using sequence specific hybrid capture; (2) an amplification step; and (3) a detection step using two separate sequence-specific polynucleotide probes. Also provided are nucleic acids comprising SEQ ID NO: 1 to SEQ ID NO: 727 and nucleic acid probes and probe sets comprising the same.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: June 27, 2017
    Assignee: QIAGEN GAITHERSBURG INC.
    Inventors: Dominic O'Neil, Irina Nazarenko, Holly Basham, Arvind Virmani, Shiuli Agarwal, Mridula Shukla
  • Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
    Patent number: 9422593
    Abstract: Methods and materials for determining the presence of at least one nucleic acid in a sample are provided, said methods comprising (1) a purification step using sequence specific hybrid capture; (2) an amplification step; and (3) a detection step comprising contacting the target nucleic acid with a plurality of detectably labeled nucleic acid detection probes, wherein each (a) bears a different detectable label from the other detection probes, and/or (b) has a different melting temperature from probes bearing the same detectable label. Also disclosed are compositions and kits for use in such a method.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: August 23, 2016
    Assignee: QIAGEN GAITHRESBURG, INC
    Inventors: Thomas Rothmann, Irina Nazarenko, Dominic O'Neil, Arvind Virmani, Brian Lowe, Shiuli Agarwal, Holly Basham
  • METHODS AND COMPOSITIONS FOR SEQUENCE-SPECIFIC PURIFICATION AND MULTIPLEX ANALYSIS OF NUCLEIC ACIDS
    Publication number: 20120045756
    Abstract: Methods and materials for determining the presence of at least one nucleic acid in a sample are provided, said methods comprising (1) a purification step using sequence specific hybrid capture; (2) an amplification step; and (3) a detection step comprising contacting the target nucleic acid with a plurality of detectably labeled nucleic acid detection probes, wherein each (a) bears a different detectable label from the other detection probes, and/or (b) has a different melting temperature from probes bearing the same detectable label. Also disclosed are compositions and kits for use in such a method.
    Type: Application
    Filed: May 18, 2011
    Publication date: February 23, 2012
    Applicant: QIAGEN GAITHERSBURG, INC.
    Inventors: Thomas ROTHMANN, Irina NAZARENKO, Dominic O'NEIL, Arvind VIRMANI, Brian LOWE, Shiuli AGARWAL, Holly BASHAM
  • METHODS AND COMPOSITIONS FOR SEQUENCE-SPECIFIC PURIFICATION AND MULTIPLEX ANALYSIS OF NUCLEIC ACIDS
    Publication number: 20110217705
    Abstract: Methods and materials for determining the presence of at least one nucleic acid in a sample are provided, said methods comprising (1) a purification step using sequence specific hybrid capture; (2) an amplification step; and (3) a detection step using two separate sequence-specific polynucleotide probes. Also provided are nucleic acids comprising SEQ ID NO: 1 to SEQ ID NO: 727 and nucleic acid probes and probe sets comprising the same.
    Type: Application
    Filed: January 28, 2011
    Publication date: September 8, 2011
    Applicant: QIAGEN GAITHERSBURG INC.
    Inventors: Dominic O'neill, Irina Nazarenko, Holly Basham, Arvind Virmani, Shiuli Agarwal