Patents by Inventor Holly Showalter

Holly Showalter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8673370
    Abstract: A nutritional supplement including ?-cryptoxanthin is found to be effective at lowering blood pressure in mammals. ?-cryptoxanthin therefore may be used to maintain cardiovascular health by lowering blood pressure, preventing high, elevated blood pressure and/or maintaining healthy blood pressure. Administration of ?-cryptoxanthin in combination with safflower oil is particularly effective.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: March 18, 2014
    Assignee: .Kemin Foods, L.C.
    Inventors: Holly Showalter, Zoraida DeFreitas, Luke Mortensen
  • Publication number: 20120053247
    Abstract: A nutritional supplement including ?-cryptoxanthin is found to be effective at lowering blood pressure in mammals. ?-cryptoxanthin therefore may be used to maintain cardiovascular health by lowering blood pressure, preventing high, elevated blood pressure and/or maintaining healthy blood pressure. Administration of ?-cryptoxanthin in combination with safflower oil is particularly effective.
    Type: Application
    Filed: August 19, 2011
    Publication date: March 1, 2012
    Inventors: Holly Showalter, Zoraida DeFreitas, Luke Mortensen
  • Patent number: 8097762
    Abstract: The present invention relates to a process for converting lutein and/or lutein esters to (3R)-?-cryptoxanthin and (3R,6?R)-?-cryptoxanthin, suitable for human consumption as dietary supplements, by employing safe and environmentally friendly reagents. (3R)-?-Cryptoxanthin and (3R,6?R)-?-cryptoxanthin are two rare food carotenoids that are not commercially available and the former exhibits vitamin A activity. In the first synthetic step, commercially available lutein and/or lutein esters are transformed into a mixture of dehydration products of lutein (anhydroluteins) in the presence of a catalytic amount of an acid. The resulting anhydroluteins are then converted to (3R)-?-cryptoxanthin (major product) and (3R,6?R)-?-cryptoxanthin (minor product) by heterogeneous catalytic hydrogenation employing transition elements of group VIII (Pt, Pd, Rh supported on alumina or carbon) in a variety of organic solvents under atmospheric pressure of hydrogen and at temperatures ranging from ?15° C. to 40° C.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: January 17, 2012
    Assignee: University of Maryland, College Park
    Inventors: Frederick Khachik, Yufa Liu, Holly Showalter
  • Patent number: 8021698
    Abstract: A nutritional supplement including ?-cryptoxanthin is found to be effective at lowering blood pressure in mammals. ?-cryptoxanthin therefore may be used to maintain cardiovascular health by lowering blood pressure, preventing high, elevated blood pressure and/or maintaining healthy blood pressure. Administration of ?-cryptoxanthin in combination with safflower oil is particularly effective.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: September 20, 2011
    Assignee: Kemin Foods, L.C.
    Inventors: Holly Showalter, Zoraida DeFreitas, Luke Mortensen
  • Publication number: 20100280286
    Abstract: The present invention relates to a process for converting lutein and/or lutein esters to (3R)-?-cryptoxanthin and (3R,6?R)-?-cryptoxanthin, suitable for human consumption as dietary supplements, by employing safe and environmentally friendly reagents. (3R)-?-Cryptoxanthin and (3R,6?R)-?-cryptoxanthin are two rare food carotenoids that are not commercially available and the former exhibits vitamin A activity. In the first synthetic step, commercially available lutein and/or lutein esters are transformed into a mixture of dehydration products of lutein (anhydroluteins) in the presence of a catalytic amount of an acid. The resulting anhydroluteins are then converted to (3R)-?-cryptoxanthin (major product) and (3R,6?R)-?-cryptoxanthin (minor product) by heterogeneous catalytic hydrogenation employing transition elements of group VIII (Pt, Pd, Rh supported on alumina or carbon) in a variety of organic solvents under atmospheric pressure of hydrogen and at temperatures ranging from ?15° C. to 40° C.
    Type: Application
    Filed: July 12, 2010
    Publication date: November 4, 2010
    Applicant: University of Maryland, College Park
    Inventors: Frederick KHACHIK, Yufa Liu, Holly Showalter
  • Publication number: 20080233222
    Abstract: A nutritional supplement including ?-cryptoxanthin is found to be effective at lowering blood pressure in mammals. ?-cryptoxanthin therefore may be used to maintain cardiovascular health by lowering blood pressure, preventing high, elevated blood pressure and/or maintaining healthy blood pressure. Administration of ?-cryptoxanthin in combination with safflower oil is particularly effective.
    Type: Application
    Filed: December 20, 2007
    Publication date: September 25, 2008
    Inventors: Holly Showalter, Zoraida DeFreitas, Luke Mortensen
  • Publication number: 20060088631
    Abstract: The present invention relates to a process for converting lutein and/or lutein esters to (3R)-?-cryptoxanthin and (3R,6?R)-?-cryptoxanthin, suitable for human consumption as dietary supplements, by employing safe and environmentally friendly reagents. (3R)-?-Cryptoxanthin and (3R,6?R)-?-cryptoxanthin are two rare food carotenoids that are not commercially available and the former exhibits vitamin A activity. In the first synthetic step, commercially available lutein and/or lutein esters are transformed into a mixture of dehydration products of lutein (anhydroluteins) in the presence of a catalytic amount of an acid. The resulting anhydroluteins are then converted to (3R)-?-cryptoxanthin (major product) and (3R,6?R)-?-cryptoxanthin (minor product) by heterogeneous catalytic hydrogenation employing transition elements of group VIII (Pt, Pd, Rh supported on alumina or carbon) in a variety of organic solvents under atmospheric pressure of hydrogen and at temperatures ranging from ?15° C. to 40° C.
    Type: Application
    Filed: October 26, 2004
    Publication date: April 27, 2006
    Inventors: Frederick Khachik, Yufa Liu, Holly Showalter