Patents by Inventor Holm Bussler

Holm Bussler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINED INHIBITION OF SEMAPHORIN-4D AND TGF-BETA AND COMPOSITIONS THEREFOR
    Publication number: 20210032322
    Abstract: Provided herein are methods for inhibiting, delaying, or reducing tumor growth and metastases of plexin-B1, plexin-B2, and/or CD72-expressing cancer cells in a subject, comprising administering to the subject an effective amount of an isolated binding molecule which specifically binds to semaphorin-4D (SEMA4D) in combination with an effective amount of antibody or antigen-binding fragment thereof that inhibits TGF?, and, optionally, at least one other immune modulating therapy.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 4, 2021
    Applicant: Vaccinex, Inc.
    Inventors: Elizabeth E. Evans, Holm Bussler