Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of A? plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

Abstract: A foldable personal such as a tricycle which can be convertible into a stroller, is configured for accommodating a child therein and for preventing, when desired, the child from being able to steer the vehicle, vehicle having an operational state and a storage state, in which it can take an extremely compact form. The vehicle has a longitudinal axis lying in its vertical plane of symmetry and having a horizontal reference plane perpendicular to the plane of symmetry, and it takes its compact form in the storage state both in the direction along its longitudinal axis and in the directions perpendicular to this axis both along the plane of symmetry and perpendicular to the plane of symmetry.

Abstract: Described is a hybrid transportation system with hybrid vehicles (H-vehicles) that can travel on pavement (or off-road), then transition to railroad track travel, and then later transition back onto pavement without stopping or requiring an operator to exit the vehicle. At static rail junctions (with no moving switch parts) the H-vehicle selects its outgoing track. Turns at passive junctions are made by applying lateral force which may be applied using multiple methods including side roller diverters and steering. Separate road wheels and rail wheels may be employed on an H-vehicle, or a combination wheel can be used with concentric road and rail wheel components. Combination wheels may be locked together or unlocked with relative rotational angular velocities. Transition between road and rail travel is facilitated using transition spans which connect roads to rails.

Abstract: Described is a hybrid transportation system with hybrid vehicles (H-vehicles) that can travel on pavement (or off-road), then transition to railroad track travel, and then later transition back onto pavement without stopping or requiring an operator to exit the vehicle. At static rail junctions (with no moving switch parts) the H-vehicle selects its outgoing track. Turns at passive junctions are made by applying lateral force which may be applied using multiple methods including side roller diverters, dual flange rail wheels, and steering. Separate road wheels and rail wheels may be employed on an H-vehicle, or a combination wheel can be used with concentric road and rail wheel components. Combination wheels may be locked together or unlocked with relative rotational angular velocities. Transition between road and rail travel is facilitated using transition spans which connect roads to rails. Improved rail-only vehicles (R-) vehicles and junctions are also described.

Abstract: A method comprising detecting an activation of an intelligent assistant on an electronic device, waking up the intelligent assistant from a sleep mode in response to the activation, and determining an amount of vocabulary the intelligent assistant acts upon during a listening mode based on a type of the activation.

Abstract: A method is disclosed for performing timing advance command (TAC) updates, comprising: configuring an appropriate block error rate (BLER); forwarding a timing advance command (TAC) for a radio network temporary identifier (RNTI) x to a user equipment (UE), the TAC not equal to 31; tracking a time of receipt of a first downlink shared channel (DLSCH) protocol data unit (PDU) with redundancy version (RV) 0 at the user equipment (UE); adding k slots; and continuing tracking timing advance (TA) samples of the radio network temporary identifier (RNTI) x, where k may be based on the subcarrier spacing.

Abstract: The field of the invention relates to systems and methods for creating on-line transactional statements, and more particularly to creating electronic transactional statements that can responsively and dynamically fit any display window size. In an embodiment, a responsive transactional statement generation system having one or more processors and a non-transitory computer-readable medium containing program instructions that cause said one or more processors to receive data files each includes data representing one or more transactional statements, parse the received data files using one or more predetermined schemas to create restructured electronic transactional statements, save the restructured electronic transactional statements and display the restructured electronic transactional statements responsively at a user device.

Abstract: A foldable personal such as a tricycle which can be convertible into a stroller, is configured for accommodating a child therein and for preventing, when desired, the child from being able to steer the vehicle, vehicle having an operational state and a storage state, in which it can take an extremely compact form. The vehicle has a longitudinal axis lying in its vertical plane of symmetry and having a horizontal reference plane perpendicular to the plane of symmetry, and it takes its compact form in the storage state both in the direction along its longitudinal axis and in the directions perpendicular to this axis both along the plane of symmetry and perpendicular to the plane of symmetry.

Abstract: The present disclosure provides methods to detect and optionally quantify Nfl present in cerebrospinal fluid and blood and use of the methods to detect and optionally measure levels of Nfl biomarkers indicative of neuronal damage. Also disclosed are anti-Nfl antibodies.

Abstract: Knit scaffolds for culturing cells and aiding in the healing of functional tissue are provided. The knit scaffolds have properties aligned with specific tissues for providing optimal tissue growing surfaces including matched biomechanical properties. The scaffolds are made up of knitted material and do not require or utilize a support skeleton for function. Methods of making and using the knit scaffolds are also provided.

Abstract: A system and method for providing secure transaction data access to trusted third parties are disclosed. An example embodiment is configured to: establish a data connection between a user platform including a data processor and a network connection, a digital exchange blockchain for storage and processing of digital assets using a consensus network protocol, and a Trusted Transparent Transaction (T3) service provider; provision a key for use by an institution to access transaction data collected by the T3 service provider; collect transaction data associated with a digital asset transfer transaction between the user platform and the blockchain; store the transaction data in a database; and enable the institution to access the transaction data by use of the provisioned key.

Abstract: A volumetric weaving approach employs a vertical aspect of woven warp and weft fibers to generate volumetric structures through formation of tie-downs. Tie downs define warp and weft fibers that take a vertical path or component extending perpendicular to a weave plane. Independently controlled heddles provide selective warp fibers control, and a two-dimensional creel that dispenses the warp fibers at differing feed rates allows manipulation of the fibers into three dimensional structures or portions. As a shuttle draws the weft fiber, different layers are raised and lowered to lend a vertical axis to the resulting volumetric structure. Interconnections between the portions include the use of the tie downs to connect multiple portions to define 3-dimensional panels of a finished article such as a shoe. A single pass defining all the interconnected portions of the shoe generates the fully formed shoe without subsequent cutting and seaming of different textile panels.

Abstract: The invention relates to treatments for fibrosis by administering a neutrophil elastase inhibitor, such as alvelestat. In particular, the invention relates to treatments for fibrosis in combination with another disease, such as organ rejection, for example bronchiolitis obliterans syndrome optionally associated with graft-versus-host-disease.

Abstract: The present disclosure encompasses anti-TREM-2 antibodies that promote TREM-2 activation and methods of using the anti-TREM-2 agonist antibodies therapeutically.

Abstract: In one embodiment, a method includes transmitting a plurality of beamformed reference signals using a corresponding plurality of beamforming precoders; receiving from each of the plurality of UEs a signal quality metric for at least a subset of the plurality of beamformed reference signals; determining a beam-specific cross-correlation for pairs of the plurality of UEs using the signal quality metrics; determining one or more scheduling groups of UEs from the plurality of UEs based on the beam-specific cross-correlation for pairs of the plurality of UEs; and allocating a set of time-frequency resource elements to two or more UEs selected from one of the determined scheduling groups.

Abstract: The present disclosure relates to targeting Respiratory Syncytial Virus (RSV), and methods of using such vaccines to treat infections with RSV, in particular, lower respiratory tract infections (LRTIs).

Abstract: A constant amplitude Radio Frequency (RF) signal is created by ordering complex information bearing symbols in the frequency domain along with their complex conjugates, and performing an inverse Fourier transform. This produces an analytic real-only transformed baseband signal. The real-only baseband signal is used to linearly vary the phase angle of a carrier wave while its amplitude remains constant. After reception, multi-path distortion is canceled. A time series of recovered phase angle is un-transformed with a FFT (fast Fourier transform) to produce I (in-phase) and Q (quadrature) samples. Demodulation occurs in a receiver by recovering carrier's phase angle vs. time. Forward error correction may be applied to data if desired. This may be called PM-OFDM (Phase Modulated-orthogonal frequency division multiplexing).

Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of A? plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

Abstract: A system and method for determining event discrepancies between disparate systems is described. The system can receive sets of events from multiple systems. The system can normalize the sets of events to convert them into normalized events. From a normalized set of events, the system can concurrently generate a plurality of event arrays. The system can apply one or more rules to the event arrays to generate at least one event array parameter.

Abstract: A liquid product spray dispenser includes a liquid spray pump and cartridge containing personal care liquid product and is adapted for cartridge replacement to facilitate personalized product replenishment. The dispenser comprises a pump assembly and a housing for containing a replaceable cartridge containing a personal care liquid. To avoid mess, the cartridge includes a tube and pump engine adapter to facilitate replacement of spent cartridges. The cartridge may be releasably secured to the dispenser or pump assembly such that a user may remove the cartridge from the dispenser or pump and replace the cartridge with another cartridge containing the same or a different product.