Patents by Inventor Hon-Ming Lam

Hon-Ming Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8062996
    Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: November 22, 2011
    Assignee: New York University
    Inventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Patent number: 7994390
    Abstract: Provided herein are the protein and nucleic acid sequences of GmRD22. Further provided herein are methods for conferring abiotic stress tolerance to a plant cell or plant by introducing and expressing an isolated polynucleotide encoding a GmRD22 protein in the cells of the plant. Transgenic plants transformed with an isolated polynucleotide encoding a GmRD22 protein, as well as seeds and progeny derived from these plants, are also provided.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: August 9, 2011
    Assignee: The Chinese University of Hong Kong
    Inventors: Hon-Ming Lam, Samuel Sai Ming Sun, Gui Hua Shao
  • Patent number: 7994393
    Abstract: The disclosed invention relates to expression systems that effect production of a protein in plants that confers resistance to trauma. The expression systems are used to modify plants to improve their resistance to infections and wounding.
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: August 9, 2011
    Assignee: The Chinese University of Hong Kong
    Inventors: Hon-Ming Lam, Sai Ming Samuel Sun
  • Patent number: 7994392
    Abstract: Expression systems that effect production of a GTPase activating protein in plants are used to modify plants to enhance their ability to resist trauma.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: August 9, 2011
    Assignee: The Chinese University of Hong Kong
    Inventors: Hon-Ming Lam, Samuel Sai Ming Sun
  • Patent number: 7939712
    Abstract: Methods to alleviate abiotic stress by modifying plants or plant cells to contain a heterologous nucleic acid that comprises a nucleotide sequence encoding the purple acid phosphatase activity of soybean GmPAP3 fused to a mitochondrion-targeting transit peptide are disclosed. Such abiotic stress can include enhanced salinity, dehydration and oxidative stress.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: May 10, 2011
    Assignee: The Chinese University of Hong Kong
    Inventors: Hon-Ming Lam, Samuel Sai Ming Sun, Gui Hua Shao
  • Patent number: 7939711
    Abstract: The invention describes a method of enhancing the expression of nucleotide sequences encoding proteins that comprise at least a DnaJ-type J-domain, in particular GmDNJ1, in plants or plant cells. Overexpression of the proteins protects plants or plant cells from salinity, osmotic, or dehydration stress.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: May 10, 2011
    Assignee: The Chinese University of Hong Kong
    Inventors: Hon-Ming Lam, Samuel Sai Ming Sun, Gui Hua Shao
  • Publication number: 20100313296
    Abstract: The disclosed invention relates to expression systems that effect production of a protein in plants that confers resistance to trauma. The expression systems are used to modify plants to improve their resistance to infections and wounding.
    Type: Application
    Filed: June 24, 2008
    Publication date: December 9, 2010
    Inventors: Hon-Ming Lam, Sai Ming Samuel Sun
  • Publication number: 20090038029
    Abstract: Plants can be modified to resist abiotic stress by effecting expression of PAP activity.
    Type: Application
    Filed: August 17, 2007
    Publication date: February 5, 2009
    Inventors: Hon-Ming Lam, Samuel Sai Ming Sun, Gui Hua Shao
  • Publication number: 20090031445
    Abstract: Expression systems that effect production of a GTPase activating protein in plants are used to modify plants to enhance their ability to resist trauma
    Type: Application
    Filed: June 18, 2008
    Publication date: January 29, 2009
    Inventors: Hon-Ming Lam, Samuel Sai Ming Sun
  • Publication number: 20080184385
    Abstract: Provided herein are the protein and nucleic acid sequences of GmRD22. Further provided herein are methods for conferring abiotic stress tolerance to a plant cell or plant by introducing and expressing an isolated polynucleotide encoding a GmRD22 protein in the cells of the plant. Transgenic plants transformed with an isolated polynucleotide encoding a GmRD22 protein, as well as seeds and progeny derived from these plants, are also provided.
    Type: Application
    Filed: September 28, 2007
    Publication date: July 31, 2008
    Inventors: Hon-Ming Lam, Samuel Sai Ming Sun, Gui Hua Shao
  • Publication number: 20080109920
    Abstract: Enhancing the expression of nucleotide sequences encoding proteins that comprise at least a DnaJ-type J-domain provides tolerance to plants or plant cells against abiotic stress, especially dehydration and salinity stress.
    Type: Application
    Filed: September 10, 2007
    Publication date: May 8, 2008
    Inventors: Hon-Ming LAM, Samuel Sun, Gui Shao
  • Publication number: 20040268431
    Abstract: The present invention is to provide a recombinant construct for transforming a plant comprising a DNA sequence encoding a recombinant human cytokine and a promoter capable of directing the expression of the recombinant human cytokine in the plant. The present invention is also to provide a method for constructing a transgenic plant, comprising the steps of transforming a plant cell with a recombinant construct of the invention, and regenerating the transgenic plant from the plant cell to produce recombinant human cytokine, for example, human granulocyte colony stimulating factor (hG-CSF), in seeds of the transgenic plant. The plant production method of the invention thus has a promising potential to mass-produce some of the most expensive biopharmaceuticals of restricted availability in a much cheaper way, which has high economic value for disease therapy, diagnosis and prevention, and is more accessible to the less affluent countries.
    Type: Application
    Filed: June 30, 2003
    Publication date: December 30, 2004
    Applicant: THE CHINESE UNIVERSITY OF HONG KONG
    Inventors: Sai Ming Samuel Sun, Ming Chiu Fung, Hon Ming Lam
  • Patent number: 6822079
    Abstract: The present invention generally relates to plant nitrogen regulatory PII gene (hereinafter P-PII gene), a gene involved in regulating plant nitrogen metabolism. The invention provides P-PII nucleotide sequences, expression constructs comprising said nucleotide sequences, and host cells and plants having said constructs and, optionally expressing the P-PII gene from said constructs. The invention also provides substantially pure P-PII proteins. The P-PII nucleotide sequences and constructs of the invention may be used to engineer organisms to overexpress wild-type or mutant P-PII regulatory protein. Engineered plants that overexpress or underexpress P-PII regulatory protein may have increased nitrogen assimilation capacity. Engineered organisms may be used to produce P-PII proteins which, in turn, can be used for a variety of purposes including in vitro screening of herbicides. P-PII nucleotide sequences have additional uses as probes for isolating additional genomic clones having the promoters of P-PII gene.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: November 23, 2004
    Assignee: New York University
    Inventors: Gloria M. Coruzzi, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Publication number: 20040002053
    Abstract: The present invention generally relates to plant nitrogen regulatory PII gene (hereinafter P-PII gene), a gene involved in regulating plant nitrogen metabolism. The invention provides P-PII nucleotide sequences, expression constructs comprising said nucleotide sequences, and host cells and plants having said constructs and, optionally expressing the P-PII gene from said constructs. The invention also provides substantially pure P-PII proteins.
    Type: Application
    Filed: January 8, 2001
    Publication date: January 1, 2004
    Applicant: New York University
    Inventors: Gloria M. Coruzzi, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Publication number: 20030022305
    Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.
    Type: Application
    Filed: August 16, 2002
    Publication date: January 30, 2003
    Applicant: New York University.
    Inventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Patent number: 6451546
    Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: September 17, 2002
    Assignee: New York University
    Inventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Patent number: 6177275
    Abstract: The present invention generally relates to plant nitrogen regulatory PII gene (hereinafter P-PII gene), a gene involved in regulating plant nitrogen metabolism. The invention provides P-PII nucleotide sequences, expression constructs comprising said nucleotide sequences, and host cells and plants having said constructs and, optionally expressing the P-PII gene from said constructs. The invention also provides substantially pure P-PII proteins. The P-PII nucleotide sequences and constructs of the inventor may be used to engineer organisms to overexpress wild-type or mutant P-PII regulatory protein. Engineered plants that overexpress or underexpress P-PII regulatory protein may have increased nitrogen assimilation capacity. Ergineered organisms may be used to produce P-PII proteins which, in turn, can be used for a variety of purposes including in vitro screening of herbicides. P-PII nucleotide sequences have additional uses as probes for isolating additional genomic clones having the promoters of P-PII gene.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: January 23, 2001
    Assignee: New York University
    Inventors: Gloria M. Coruzzi, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Patent number: 5981703
    Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.
    Type: Grant
    Filed: June 5, 1996
    Date of Patent: November 9, 1999
    Assignee: New York University
    Inventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Patent number: 5959174
    Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.
    Type: Grant
    Filed: April 8, 1996
    Date of Patent: September 28, 1999
    Inventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh
  • Patent number: 5824867
    Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 20, 1998
    Assignee: New York University
    Inventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh