Abstract: An Ethernet Physical layer (PHY) device includes a PHY interface and PHY circuitry. The PHY interface is configured to connect to a physical link. The PHY circuitry is configured to generate layer-1 frames that carry data for transmission to a peer Ethernet PHY device, to insert among the layer-1 frames one or more management frames that are separate from the layer-1 frames and that are configured to control a General-Purpose Input-Output (GPIO) port associated with the peer Ethernet PHY device, to transmit the layer-1 frames and the inserted management frames, via the PHY interface, to the peer Ethernet PHY device over the physical link, for controlling one or more operations of the GPIO port associated with the peer Ethernet PHY device, and to receive, via the PHY interface, one or more verifications acknowledging that the one or more management frames were received successfully at the peer Ethernet PHY device.

Abstract: In described examples, an apparatus comprises a multi-modulus divider (MMD) having a divider input, a divisor input, and a divider output. The apparatus also comprises a phase detector (PD) having a first clock input, a second clock input, and a PD output, the second clock input coupled to the divider output. The apparatus also comprises a phase to digital converter (P2DC) having a P2DC input and a P2DC output, the P2DC input coupled to the PD output. The apparatus further comprises a delta-sigma modulator having a third clock input, a modulator input, and a modulator output, the third clock input coupled to the divider output, the modulator input coupled to the P2DC output, and the modulator output coupled to the divisor input.

Abstract: A circuit includes cross coupled invertors including a first invertor and a second inventor. The first invertor and the second invertor are cross coupled at a first data node and a second data node. An input unit is coupled between the cross-coupled invertors and a power node. The input unit controls the cross-coupled invertors in response to a first input signal received at a first input terminal of the input unit and a second input signal received at a second input terminal of the input unit. A first transistor is connected between the power node and a supply node. The first transistor connects the power node to the supply node in response to an enable signal changing to a first value. A second transistor is connected between the power node and ground. The second transistor connects the power node to the ground in response to the enable signal changing to a second value.

Abstract: A reflexive training apparatus for mixed martial arts training. The training apparatus includes limbs with joints that simulate actual human joints and also simulate how a human joint would respond to different pressures, bars, locks, holds, breaks, and hyperextensions. In addition, the training apparatus is configured to go into several guard positions and to respond to a user's actions in a manner similar to how a real opponent would respond during a grappling session. In some embodiments, the training apparatus comprises a composite of materials that make the training apparatus sturdy enough to simulate the weight and feel of an actual person.

Abstract: An inedible and dry dormant state encapsulated probiotic core-shell particle for external, non-mucosal skin application is provided. From inside out, the core-shell particle has a structure of a carrier particle core serving as a nutrient source for probiotics, a first layer including a dormant probiotic species for affecting epidermal biome and at least one prebiotic as a food source for the probiotic, a polymer layer positioned over the first layer, and a dissolvable protective layer for protecting the probiotic core-shell particle from oxidation, heat and humidity. By co-applying with a releasing medium, the dissolvable protective layer and the polymer layer are dissolved to expose the dormant probiotic containing layer, the first layer. Further, the releasing medium also is able to activate and reconstitute the dormant probiotic to a live probiotic on the applied non-mucosal epidermal surface.

Abstract: A lighting apparatus includes a light emitting diode, in which the light emitting diode includes an n-type nitride semiconductor layer, an active layer located on the n-type nitride semiconductor layer, and a p-type nitride semiconductor layer located on the active layer. The light emitting diode emits light that varies from yellow light to white light depending on a driving current.

Abstract: In various examples, a current claimed set of points representative of a volume in an environment occupied by a vehicle at a time may be determined. A vehicle-occupied trajectory and at least one object-occupied trajectory may be generated at the time. An intersection between the vehicle-occupied trajectory and an object-occupied trajectory may be determined based at least in part on comparing the vehicle-occupied trajectory to the object-occupied trajectory. Based on the intersection, the vehicle may then execute the first safety procedure or an alternative procedure that, when implemented by the vehicle when the object implements the second safety procedure, is determined to have a lesser likelihood of incurring a collision between the vehicle and the object than the first safety procedure.

Abstract: A memory device that includes at least one memory cell is introduced. Each of the at least one memory cell is coupled to a bit line and a word line. Each of the at least one memory cell includes a memory element and a selector element, in which the memory element is configured to store data of the at least one memory cell. The selector element is coupled to the memory element in series and is configured to select the memory element for a read operation and amplify the data stored in the memory element in the read operation.

Abstract: Disclosed herein are heterocyclic compounds that inhibit the binding of menin and MLL or MLL fusion proteins. Also described are specific irreversible inhibitors of menin-MLL interaction. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the menin-MLL irreversible inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, leukemia and other diseases or conditions dependent on menin-MLL interaction.

Abstract: Methods and systems for maintaining and building an autonomous vehicle-related event blockchain are provided. One or more processors may receive indications of autonomous vehicle events. The autonomous vehicle events may include information relating to technology usage and/or operational events. The autonomous vehicle events may be compiled into a log of recorded autonomous vehicle events. Based upon the autonomous vehicle events, an action to implement may be determined. Additionally, the log may be distributed to a public or private network of distributed nodes to form a consensus on an update to the log of record autonomous vehicle events. As a result, the distributed nodes may maintain an up-to-date record of the shared ledger of autonomous vehicle events.

Abstract: A first communication device generates an Operation, Administration, and Maintenance (OAM) frame that includes i) OAM message content and ii) an OAM frame header outside of the OAM message content, wherein generating the OAM frame comprises generating the OAM frame header to include information that signals one of i) a low power sleep (LPS) request, and ii) a wake-up request (WUR). The first communication device transmits the OAM frame to a second communication device via a communication medium to signal to the second communication device the one of i) the LPS request, and ii) the WUR.

Abstract: A point to point radio alignment system is disclosed. A voltmeter positioned at the first antenna measures alignment voltage that is generated from an alignment of the first radio component positioned on the first antenna. A transceiver positioned at the first antenna receives a second alignment voltage that is measured at the second antenna and generated from an alignment of the second radio component positioned on the second antenna. A controller positioned at the first antenna simultaneously monitors the first alignment voltage as the alignment of the first radio component is adjusted and the second alignment voltage as the second radio component is adjusted. The controller simultaneously displays the first alignment voltage as the first radio component is adjusted and the second alignment voltage as the second radio component is adjusted to enable a first user to track an alignment of the first radio component and the second radio component.

Abstract: A reference circuit for generating a reference current includes a plurality of resistive elements including at least one magnetic tunnel junction (MTJ). A control circuit is coupled to a first terminal of the at least one MTJ and is configured to selectively flow current through the at least one MTJ in the forward and inverse direction to generate a reference current.

Abstract: Forced expression of a handful of transcription factors (TFs) can induce conversion between cell identities; however, the extent to which TFs can alter cell identity has not been systematic ally assessed. Here, we assembled a “human TFome,” a comprehensive expression library of 1,578 human TF clones with fall coverage of the major TF families. By systematically screening the human TFome, we identified many individual TFs that induce loss of human-induced-pluripotent-stem-cell (hiPSC) identity, suggesting a pervasive ability for TFs to alter cell identity. Using large-scale computational cell type classification trained on thousands of tissue expression pantiles, we identified cell types generated by these TFs with high efficiency and speed, without additional selections or mechanical perturbations. TF expression in adult human tissues only correlated with some of the cell lineage generated, suggesting more complexity than observation studies can explain.

Abstract: A system and method for granting access to network resources through access credentials given to an agent process running on each computer or machine where resource requesters reside. The system extends a traditional token-granting authorization system to the agent processes, where each agent has administrative access to machine information. The agent uses that access to acquire detailed information about resource requesters. Requester qualifications defined by the system limit requester access to resources, and are enforced both by the agent and by the central system on the network resource server. Resource requesters ask for a token for resource use from the agent, not the central system. The agent uses its credentials to get a token from the central system and then return the token to qualified requesters.

Abstract: An atomizing electronic cigarette has an atomizing core component and a liquid storage component. including an electric heater. The electric heater may have a through hole aligned with a channel passing through the liquid storage component. The cigarette can heat and uniformly vaporize liquid from the liquid storage component, with the user inhaling the vaporized liquid. The vapor generated by the atomizing process may be cooled as it flows through the channel.

Abstract: A system and a method are disclosed for providing recommendations for sets of security operations for improving security of documents created or executed within an online document system. A supplier entity may select sets of security operations to be performed for a request provided to a signing entity. The online document system computes an aggregate measure of security for the selected sets of security operations and compares it to a threshold measure of security. If the aggregate measure is less than the threshold measure, the online document system uses a machine-learned model to identify additional sets of security operations that when added, results in an updated aggregate measure of security greater than the threshold. The additional sets of security operations are presented to the supplier entity for inclusion within a security operation workflow in combination with the selected sets of security operations.

Abstract: A method of fabricating a device includes providing a fin element in a device region and forming a dummy gate over the fin element. In some embodiments, the method further includes forming a source/drain feature within a source/drain region adjacent to the dummy gate. In some cases, the source/drain feature includes a bottom region and a top region contacting the bottom region at an interface interposing the top and bottom regions. In some embodiments, the method further includes performing a plurality of dopant implants into the source/drain feature. In some examples, the plurality of dopant implants includes implantation of a first dopant within the bottom region and implantation of a second dopant within the top region. In some embodiments, the first dopant has a first graded doping profile within the bottom region, and the second dopant has a second graded doping profile within the top region.

Abstract: IV filters are described herein. An IV filter includes a filter housing, a filter media, a filter channel, a priming channel, and a disk valve. The filter housing defines an inlet and an outlet. The filter media is disposed within the filter housing. The filter channel is disposed within the filter housing. The filter channel is in fluid communication with the inlet and the filter media, and the filter media permits flow from the filter channel to the outlet and captures particulate from the flow. The priming channel is disposed within the filter housing. The priming channel is in fluid communication with the inlet and the outlet. The disk valve is coupled to the filter housing. The disk valve is moveable to direct flow from the inlet to the priming channel in a first position and to direct flow from the inlet to the filter channel in a second position.

Abstract: The disclosure is directed to an electronic device with a lid to manage radiation feedback. The electronic device includes a lid having at least one sidewall and a top wall, as well as a semiconductor positioned within a cavity of the lid. In certain embodiments, the lid includes at least one dielectric material and at least one internal conductive layer at least partially embedded within the at least one dielectric material. In certain embodiments, the lid includes dielectric material, as well as an internal wall extending from the top wall and positioned between an input port and an output port of the semiconductor. Such configurations may suppress any undesirable feedback through the lid between the input port and the output port of the semiconductor.