Patents by Inventor Hon-Wah Lam

Hon-Wah Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220106621
    Abstract: The present invention relates to a system for detecting a target enzyme in a sample, the system including a substrate, a first enzyme immobilized on the substrate via a first linker, and a second enzyme immobilized on the substrate via a second linker, wherein the first linker is cleavable by the target enzyme or the second enzyme to release the first enzyme for cleaving the second linker, thereby releasing the second enzyme; and a method for detecting a target enzyme in a sample including applying the sample to said system.
    Type: Application
    Filed: October 6, 2020
    Publication date: April 7, 2022
    Inventors: Hon-wah Lam, Chuanwen Zhou
  • Patent number: 11181501
    Abstract: A method and an apparatus for determining a presence or an amount of a polyamine or its derivative in a sample, the method including: applying the sample on an electrochemical detector having a substance selection structure, wherein the substance selection structure is sensitive to the polyamine or its derivative; applying at least one voltage bias to the electrochemical detector; and detecting a change of electrical characteristics of the electrochemical detector so as to determine the presence or the amount of the polyamine or its derivative in the sample.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: November 23, 2021
    Assignee: City University of Hong Kong
    Inventors: A. L. Roy Vellaisamy, Chi-Chung Yeung, Shishir Venkatesh, Hon-Wah Lam
  • Publication number: 20200080960
    Abstract: A method and an apparatus for determining a presence or an amount of a polyamine or its derivative in a sample, the method including: applying the sample on an electrochemical detector having a substance selection structure, wherein the substance selection structure is sensitive to the polyamine or its derivative; applying at least one voltage bias to the electrochemical detector; and detecting a change of electrical characteristics of the electrochemical detector so as to determine the presence or the amount of the polyamine or its derivative in the sample.
    Type: Application
    Filed: September 11, 2018
    Publication date: March 12, 2020
    Inventors: A.L. Roy Vellaisamy, Chi-Chung Yeung, Shishir Venkatesh, Hon-Wah Lam
  • Patent number: 9983185
    Abstract: A chemosensing hydrogel is provided that undergoes a colorimetric reaction in response to the detection of a biogenic amine vapor, such as a biogenic amine vapor that is a by-product resulting from food spoilage. In an embodiment, an apparatus for detection of biogenic amines, is provided that includes a hydrogel having a bimetallic iron(II)-iron(III) complex disposed within the hydrogel, wherein the hydrogel is configured to change from a first color to a second color in response to exposure to a biogenic amine.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: May 29, 2018
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventor: Hon-Wah Lam
  • Publication number: 20170219549
    Abstract: A chemosensing hydrogel is provided that undergoes a colorimetric reaction in response to the detection of a biogenic amine vapor, such as a biogenic amine vapor that is a by-product resulting from food spoilage. In an embodiment, an apparatus for detection of biogenic amines, is provided that includes a hydrogel having a bimetallic iron(II)-iron(III) complex disposed within the hydrogel, wherein the hydrogel is configured to change from a first color to a second color in response to exposure to a biogenic amine.
    Type: Application
    Filed: February 1, 2016
    Publication date: August 3, 2017
    Inventor: Hon-Wah LAM
  • Patent number: 8338553
    Abstract: Disclosed are a solvatochromic functional monomer having the chemical structure and a process for preparing the same. The solvatochromic functional monomer can be used for fabrication of molecularly imprinted polymer based (MIP-based) solvatochromic chemosensors. This involves the incorporation of the solvatochromic functional monomer as reporter into the molecularly imprinted polymer. The solvatochromic functional monomers as reporters signal the analyte-to-receptor displacing event within the receptor sites without the need for intermolecular interaction between the analyte and the receptor.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: December 25, 2012
    Assignee: City University of Hong Kong
    Inventors: Hon-Wah Lam, Chengbin Gong
  • Patent number: 8288165
    Abstract: The invention relates to using heterobimetallic coordination polymers and their uses as chemodosimeters for sensing materials for the screening of specific biogenic amines.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: October 16, 2012
    Assignee: City University of Hong Kong
    Inventors: Hon-Wah Lam, Cheuk-Fai Chow
  • Publication number: 20110306140
    Abstract: The invention relates to using heterobimetallic coordination polymers and their uses as chemodosimeters for sensing materials for the screening of specific biogenic amines.
    Type: Application
    Filed: June 10, 2010
    Publication date: December 15, 2011
    Applicant: CITY UNIVERSITY OF HONG KONG
    Inventors: Hon-Wah LAM, Cheuk-Fai CHOW
  • Publication number: 20110003397
    Abstract: The present invention relates to a solvatochromic functional monomer having the chemical structure as shown in the accompanying drawing (FIG. 3), and a process for preparing the solvatochromic functional monomer (FIG. 2). The solvatochromic functional monomer can be used for fabrication of molecularly imprinted polymer based (MIP-based) solvatochromic chemosensors. This involves the incorporation of the solvatochromic functional monomer as reporter into the molecularly imprinted polymer. The solvatochromic functional monomers as reporters signal the analyte-to-receptor displacing event within the receptor sites without the need of intermolecular interaction between the analyte and receptor. The invention also relates to a MIP-based solvatochromic chemosensing approach. This involves the combination of solvatochromism and molecular imprinting technique in the chemosensing of target analytes.
    Type: Application
    Filed: July 1, 2009
    Publication date: January 6, 2011
    Applicant: City University of Hong Kong
    Inventors: Hon-Wah Lam, Chengbin Gong