Patents by Inventor Hon Wai Koon

Hon Wai Koon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTION AND TREATMENT OF INTESTINAL FIBROSIS
    Publication number: 20230405078
    Abstract: Methods and materials for measuring semm elafin levels, elevated levels of which have been confirmed to detect the presence of stricture in patients with Crohn's disease (CD), and a method for improving the accuracy of detecting the presence of stricture through the use of an algorithm developed through machine learning and/or through the use of clinical data. Further, materials and methods for treating intestinal stricture in a subject having Crohn's disease, as well as for inhibiting intestinal fibrosis, inflammatory bowel disease (IBD), metabolic disease, or obesity in a subject, comprises administering elafin to the subject.
    Type: Application
    Filed: March 26, 2021
    Publication date: December 21, 2023
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Hon Wai Koon, Charalabos Pothoulakis
  • Inflammatory bowel disease markers and therapies for colitis-associated intestinal fibrosis
    Patent number: 9772334
    Abstract: Method of diagnosing and treating inflammatory bowel disease are disclosed herein. Inflammatory bowel disease can be treated and diagnosed using cathelicidin peptides and detection agents thereof. Specifically, method of treating and diagnosing Crohn's disease and ulcerative colitis are disclosed herein.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: September 26, 2017
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Hon Wai Koon, Charalabos Pothoulakis, Avinoam Dukler
  • Cathelicidin as novel inflammatory bowel disease marker and therapy for colitis associated intestinal fibrosis
    Patent number: 9651562
    Abstract: Method of diagnosing and treating inflammatory bowel disease are disclosed herein. Inflammatory bowel disease can be treated and diagnosed using cathelicidin peptides and detection agents thereof. Specifically, method of treating and diagnosing Crohn's disease and ulcerative colitis are disclosed herein.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: May 16, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Hon Wai Koon, Charalabos Pothoulakis
  • NOVEL INFLAMMATORY BOWEL DISEASE MARKERS AND THERAPIES FOR COLITIS-ASSOCIATED INTESTINAL FIBROSIS
    Publication number: 20160161501
    Abstract: Method of diagnosing and treating inflammatory bowel disease are disclosed herein. Inflammatory bowel disease can be treated and diagnosed using cathelicidin peptides and detection agents thereof. Specifically, method of treating and diagnosing Crohn's disease and ulcerative colitis are disclosed herein.
    Type: Application
    Filed: June 18, 2015
    Publication date: June 9, 2016
    Inventors: Hon Wai KOON, Charalabos POTHOULAKIS, Avinoam DUKLER
  • CATHELICIDIN AS NOVEL INFLAMMATORY BOWEL DISEASE MARKER AND THERAPY FOR COLITIS-ASSOCIATED INTESTINAL FIBROSIS
    Publication number: 20150293123
    Abstract: Method of diagnosing and treating inflammatory bowel disease are disclosed herein. Inflammatory bowel disease can be treated and diagnosed using cathelicidin peptides and detection agents thereof. Specifically, method of treating and diagnosing Crohn's disease and ulcerative colitis are disclosed herein.
    Type: Application
    Filed: December 10, 2013
    Publication date: October 15, 2015
    Inventors: Hon Wai Koon, Charalabos Pothoulaks