Abstract: Provided are a crucible combination and a thermal field assembly. The crucible combination includes a susceptor holder; a susceptor body disposed on the susceptor holder, the susceptor body comprises a crucible installation cavity that gradually increases from the susceptor holder in a direction departing from the susceptor holder; and a crucible disposed in the crucible installation cavity, an outer surface of the crucible is an outer surface that gradually increases from the susceptor holder in the direction departing from the susceptor holder, the outer surface and an inner surface of the crucible installation cavity are arranged oppositely, and a softening temperature of the susceptor body is greater than the softening temperature of the crucible.

Abstract: A cluster management method includes starting an operating system of a network device and feeding back a startup result of an operating system. The cluster management system sends the startup indication to the computing device to control to start the computing device and the operating system of the network device included in the computing device, and the computing device feeds back the startup result.

Abstract: The present application belongs to the technical field of gene therapy, and discloses a method for treating a tumor with a combination of an exogenous antigen and a therapeutic agent. The present application also discloses a composition including an exogenous antigen and a therapeutically effective amount of a therapeutic agent. With the exogenous antigen as a target, the therapeutic agent kills a tissue or cell carrying the exogenous antigen and does not act on any tissue or cell without the exogenous antigen, thereby specifically killing the tissue or cell, such as a tumor cell. Since the exogenous antigen can be expressed in different types of tumors in different individuals, the method of the present application is a broad-spectrum anti-tumor method.

Abstract: A computer-implemented method, according to one approach, includes: determining whether a destination for a domain name system (DNS) query corresponds to an existing source network address translation (SNAT) port in response to receiving the DNS query. In response to determining that the destination for the DNS query corresponds to an existing SNAT port, the DNS query is modified to incorporate the existing SNAT port. A map entry corresponding to the existing SNAT port is also updated, and the modified DNS query is satisfied. Other systems, methods, and computer program products are described in additional approaches.

Abstract: The present disclosure relates to methods and compositions that inhibit a tumor microenvironment and methods of co-administering such compositions to inhibit the tumor microenvironment and treat cancer in a subject.

Abstract: A medical image segmentation method include: 1) acquiring a medical image data set; 2) acquiring, from the medical image data set, an original image and a real segmentation image of a target region in the original image in pair to serve as an input data set of a pre-built constant-scaling segmentation network, the input data set including a training set, a verification set, and a test set; 3) training the constant-scaling segmentation network by using the training set to obtain a trained segmentation network model, and verifying the constant-scaling segmentation network by using the verification set, the constant-scaling segmentation network including a feature extraction module and a resolution amplifying module; and 4) inputting the original image to be segmented into the segmentation network model for segmentation to obtain a real segmentation image.

Abstract: A dissolvable solid article which can include multiple layers of flexible, dissolvable, porous sheets, in which a coating composition including solid particles is present on at least one internal surface of at least one sheet in said solid articles and a process for making such solid articles.

Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: A gate driving device and an operating method are provided. The gate driving device includes a plurality of gate driving circuits and a control circuit. The gate driving circuits generate a plurality of gate driving signals having different timing. The control circuit is coupled to a plurality of candidate gate driving circuits among the gate driving circuits. The control circuit selects one of the candidate gate driving circuits as an initial stage gate driving circuit per one scanning cycle. A series connection mode between the gate driving circuits is changed in response to a scan selection signal.

Abstract: This application relates to the field of injection technology, especially a type of portable carbon dioxide gas injector. The technical solution of the invention includes a storage tube, one end of which is connected with a passage tube, and a passage valve is provided at the end of the passage tube away from the storage tube. A piston adapted to the injection device body is arranged inside the storage tube. A driving assembly for driving the piston is arranged on one side of the piston away from the passage tube, and a regulating assembly for adjusting the gas storage volume is arranged on the other side of the driving assembly away from the passage tube. The invention achieves quantitative control of the injection amount of carbon dioxide, which can alleviate the discomfort of patients.

Abstract: The present application discloses an ultrasonic image sensor and a related electronic device. The ultrasonic image sensor is coupled to a sinusoidal pulse signal generating circuit. The ultrasonic image sensor and the sinusoidal pulse signal generating circuit are provided below a cover plate. The ultrasonic image sensor is used to sense a surface pattern of an object to be measured that makes contact with the cover plate from above the cover plate. The ultrasonic image sensor includes: an upper electrode; a lower electrode array; a piezoelectric layer, which is provided between the upper electrode and the lower electrode array, wherein the piezoelectric layer is excited by means of a sinusoidal pulse signal generated by the sinusoidal pulse signal generating circuit so as to generate an ultrasonic wave, the ultrasonic wave is transmitted along the cover plate to the object to be measured and then a reflected echo is generated.

Abstract: Disclosed in the present application are a detection circuit and a related electronic apparatus. A detection circuit is used for determining the amplitude of a received signal that is generated by a receiver after same receives an input signal, and includes an operational amplifier; a capacitor unit, which is coupled between an output end and a negative end of the operational amplifier; a reset switch, which is arranged in parallel with the capacitor unit; a first switch, which is coupled between a reference voltage and an output end of the receiver; and a second switch, which is coupled between the output end of the receiver and the negative end of the operational amplifier, wherein in a general stage, the received signal includes a plurality of waves with a period T.

Abstract: Described herein are new pharmaceutical formulations, their preparation, and their use for pain treatment. In particular, described herein are pharmaceutical formulations of the analgesic drug Nalbuphine for intranasal administration.

Abstract: A device for treating a diseased native valve in a patient includes a frame structure and a valve segment coupled to the frame structure. The frame structure has an unexpanded configuration and an expanded configuration. The valve segment has a plurality of leaflets, a seal, and a seal support. An inflow edge of the plurality of leaflets is unsupported by the frame structure. The seal is attached to the inflow edge of the plurality of leaflets and positioned radially between the frame structure and the plurality of leaflets. The seal support is attached to or within the seal and provides axial rigidity to the seal.

Abstract: A picture generation unit comprises a light emitter array that is disposed on a substrate and provides a projection imaging light. The light emitter array includes a plurality of light emitting units. Each of the light emitting units includes a plurality of mini LED chips. An electronic control unit is electrically coupled to the substrate to control the mini LED chips to generate the projection imaging light. The light emitter array may emit light as well as present controllable images simultaneously. Because the picture generation unit abandons using the conventional backlight source and the module thereof, it can effectively utilize light energy and reduce radiation heat/waste heat. A vehicular head-up display system using the picture generation unit may improve operation reliability thereof.

Abstract: Data isolators are described. The data isolators include a differential receiver having cross-coupled single-ended amplifiers. The single-ended amplifiers may be referenced to a time-varying reference potential. The cross-coupling of the single-ended amplifiers may provide high speed, low power consumption operation of the data isolator.

Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.

Abstract: Methods, computer program products, and systems are presented. The method computer program products, and systems can include, for instance: receiving, by a Network Virtualization Edge (NVE) of a first virtual network (VN), a multicast packet from a virtual machine (VM) of the first virtual network (VN); determining, by the NVE, whether the NVE currently supports forwarding the multicast packet to a second NVE of a second virtual network (VN), the second virtual network (VN) being logically separated from the first virtual network (VN); responsively to determining that the NVE currently supports forwarding the multicast packet to a second NVE of a second virtual network (VN) forwarding, by the NVE, the multicast packet to the second NVE.

Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.

Abstract: The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): wherein R1-R3 are as defined herein, or pharmaceutically acceptable salts or esters thereof; and a pharmaceutically acceptable carrier.