Patents by Inventor Hong Hoe KOO

Hong Hoe KOO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stem cell with suppressed SOCS and improved immunosuppressive ability and use thereof
    Patent number: 10961533
    Abstract: The present invention relates to a stem cell having an immunosuppressive ability in which the expression or activity of a suppressor of cytokine signaling (SOCS) is inhibited, and a pharmaceutical composition for inhibiting immunity, which includes the stem cell. In addition, the present invention relates to a composition for inducing the immunosuppressive activity of a stem cell, including a suppressor of cytokine signaling (SOCS) expression or activity inhibitor. The inhibition of suppressor of cytokine signaling (SOCS) expression or activity, according to the present invention, may enhance the immunosuppressive ability of a stem cell, and the stem cell with enhanced immunosuppressive ability may be used as an effective cell therapeutic agent in an autoimmune disease, rejection upon organ transplantation, or an allergic disease.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: March 30, 2021
    Assignee: CELLNLIFE INC.
    Inventors: Keon Hee Yoo, Hong Hoe Koo, Myoung Woo Lee, Dae Seong Kim
  • STEM CELL WITH SUPPRESSED SOCS AND IMPROVED IMMUNOSUPPRESSIVE ABILITY AND USE THEREOF
    Publication number: 20180320178
    Abstract: The present invention relates to a stem cell having an immunosuppressive ability in which the expression or activity of a suppressor of cytokine signaling (SOCS) is inhibited, and a pharmaceutical composition for inhibiting immunity, which includes the stem cell. In addition, the present invention relates to a composition for inducing the immunosuppressive activity of a stem cell, including a suppressor of cytokine signaling (SOCS) expression or activity inhibitor. The inhibition of suppressor of cytokine signaling (SOCS) expression or activity, according to the present invention, may enhance the immunosuppressive ability of a stem cell, and the stem cell with enhanced immunosuppressive ability may be used as an effective cell therapeutic agent in an autoimmune disease, rejection upon organ transplantation, or an allergic disease.
    Type: Application
    Filed: October 31, 2016
    Publication date: November 8, 2018
    Applicant: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
    Inventors: Keon Hee YOO, Hong Hoe KOO, Myoung Woo LEE, Dae Seong KIM