Patents by Inventor Hongjian Jiang

Hongjian Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240115242
    Abstract: The present disclosure provides an ultrasound imaging method, comprising acquiring an ultrasound echo signal of a subject to be scanned, and generating an ultrasound image on the basis of the ultrasonic echo signal; identifying a section of the subject to be scanned that corresponds to the ultrasound image; determining a first anatomical feature in the ultrasound image; and determining a second anatomical feature in the ultrasound image, the determination of the second anatomical feature being at least partially based on the positional relationship between the first anatomical feature and the second anatomical feature in the section. The present disclosure also provides an ultrasound imaging system and a non-transitory computer-readable medium.
    Type: Application
    Filed: October 11, 2023
    Publication date: April 11, 2024
    Inventors: Hongjian Jiang, Siying Wang, Qing Cao
  • Patent number: 11951114
    Abstract: Methods useful for treating X-linked adrenoleukodystrophy are provided.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: April 9, 2024
    Assignees: Viking Therapeutics, Inc., Metabasis Therapeutics, Inc.
    Inventors: Brian Lian, Rochelle Hanley, Misha Dinerman, Mark Erion, Serge Boyer, Hongjian Jiang
  • Publication number: 20230346335
    Abstract: Provided in the present application is an ultrasonic imaging method including generating an ultrasound image, determining an initial position of a tracking point of an area to be tracked in the ultrasound image, receiving a first tracking instruction from an input device, and automatically moving the tracking point along the boundary of the area to be tracked for the duration of the first tracking instruction to generate a trace line. Also provided in the present application are an ultrasonic imaging system and a non-transitory computer-readable medium.
    Type: Application
    Filed: April 19, 2023
    Publication date: November 2, 2023
    Inventors: Jiajiu Yang, Yao Ding, Zhiqiang Jiang, Hongjian Jiang, Yi Wang, Yuanyuan Chen, Hujie Jiang
  • Publication number: 20220257618
    Abstract: Methods useful for treating X-linked adrenoleukodystrophy are provided.
    Type: Application
    Filed: May 6, 2022
    Publication date: August 18, 2022
    Inventors: BRIAN LIAN, Rochelle Hanley, Misha Dinerman, Mark Erion, Serge Boyer, Hongjian Jiang
  • Patent number: 11396503
    Abstract: Provided is a sulfonyl-substituted bicyclic compound (A) which acts as a ROR? inhibitor, said compound has good ROR? inhibitory activity and is expected to be used for treating diseases mediated by a ROR? receptor in mammals.
    Type: Grant
    Filed: September 30, 2018
    Date of Patent: July 26, 2022
    Assignees: Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Nanjing Gear Pharma & Tech Co., Ltd.
    Inventors: Xiaolong Wang, Anle Yang, Hongjian Jiang, Jian Zhou, Lei Chen, Xiaolong Jiang, Ling Yang, Hongjiang Xu, Xiaohan Geng
  • Patent number: 11351183
    Abstract: Methods useful for treating X-linked adrenoleukodystrophy are provided.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: June 7, 2022
    Assignees: Viking Therapeutics, Inc., Metabasis Therapeutics, Inc.
    Inventors: Brian Lian, Rochelle Hanley, Misha Dinerman, Mark Erion, Serge Boyer, Hongjian Jiang
  • Publication number: 20200239454
    Abstract: Provided is a sulfonyl-substituted bicyclic compound (A) which acts as a ROR? inhibitor, said compound has good ROR? inhibitory activity and is expected to be used for treating diseases mediated by a ROR? receptor in mammals.
    Type: Application
    Filed: September 30, 2018
    Publication date: July 30, 2020
    Applicants: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., NANJING GEAR PHARMA & TECH CO., LTD.
    Inventors: Xiaolong WANG, Anle YANG, Hongjian JIANG, Jian ZHOU, Lei CHEN, Xiaolong JIANG, Ling YANG, Hongjiang XU, Xiaohan GENG
  • Publication number: 20190321379
    Abstract: Methods useful for treating X-linked adrenoleukodystrophy are provided.
    Type: Application
    Filed: April 24, 2017
    Publication date: October 24, 2019
    Inventors: Brian Lian, Rochelle Hanley, Misha Dinerman, Mark Erion, Serge Boyer, Hongjian Jiang
  • Patent number: 10420781
    Abstract: A thyroid hormone receptor agonist and its use in the treatment of a disease associated thyroid hormone receptor beta are described. The compound can be effective in lowering cholesterol with minimum or no adverse effects on the heart or thyroid hormone axis.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: September 24, 2019
    Assignee: Metabasis Therapeutics Inc.
    Inventors: Mark Erion, Hongjian Jiang, Serge Henri Boyer
  • Patent number: 10238623
    Abstract: The present invention belongs to the field of natural medicines and medicinal chemistry, and relates to novel esterified amino acid derivatives of triptolide of general formula I and general formula II or pharmaceutically acceptable adducts, complexes, salts, and catabolites and metabolites thereof, preparation methods of these compounds, pharmaceutical compositions comprising the compound, and uses thereof in preparing drugs against tumors, immune diseases, or diseases related to abnormal expression of XPB or Pol II or oncogene c-myc.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: March 26, 2019
    Assignee: HANGZHOU WEBEN PHARMACEUTICALS INC
    Inventors: Rongzhen Xu, Hongjian Jiang
  • Publication number: 20180344752
    Abstract: A thyroid hormone receptor agonist and its use in the treatment of a disease associated thyroid hormone receptor beta are described. The compound can be effective in lowering cholesterol with minimum or no adverse effects on the heart or thyroid hormone axis.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 6, 2018
    Inventors: Mark Erion, Hongjian Jiang, Serge Henri Boyer
  • Patent number: 9895355
    Abstract: Methods for treating androgen receptor-mediated diseases, such as breast cancer, with imidazoline derivatives of formula (I) are provided:
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: February 20, 2018
    Assignees: Shanghai Hengru Pharmaceutical Co., Ltd., Jiangsu Hengrui Medicine Co., Ltd.
    Inventors: Hejun Lu, Piaoyang Sun, Hongbo Fei, Hongjian Jiang, Haowei Wang, Qing Dong
  • Publication number: 20180036277
    Abstract: The present invention belongs to the field of natural medicines and medicinal chemistry, and relates to novel esterified amino acid derivatives of triptolide of general formula I and general formula II or pharmaceutically acceptable adducts, complexes, salts, and catabolites and metabolites thereof, preparation methods of these compounds, pharmaceutical compositions comprising the compound, and uses thereof in preparing drugs against tumors, immune diseases, or diseases related to abnormal expression of XPB or Pol II or oncogene c-myc.
    Type: Application
    Filed: October 29, 2015
    Publication date: February 8, 2018
    Inventors: Rongzhen Xu, Hongjian Jiang
  • Publication number: 20170319604
    Abstract: A thyroid hormone receptor agonist and its use in the treatment of a disease associated thyroid hormone receptor beta are described. The compound can be effective in lowering cholesterol with minimum or no adverse effects on the heart or thyroid hormone axis.
    Type: Application
    Filed: April 20, 2017
    Publication date: November 9, 2017
    Inventors: Mark Erion, Hongjian Jiang, Serge Henri Boyer
  • Publication number: 20170128422
    Abstract: Methods for treating androgen receptor-mediated diseases, such as breast cancer, with imidazoline derivatives of formula (I) are provided:
    Type: Application
    Filed: January 20, 2017
    Publication date: May 11, 2017
    Inventors: Hejun LU, Piaoyang SUN, Hongbo FEI, Hongjian JIANG, Haowei WANG, Qing DONG
  • Patent number: 9586947
    Abstract: New imidazoline derivatives represented by formula (I): preparation methods thereof, pharmaceutical compositions comprising such derivatives, and applications of such derivatives in preparing androgen receptor antagonists and medicaments for treating diseases such as prostate cancer are described.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: March 7, 2017
    Assignees: Shanghai Hengrui Pharmaceutical Co., Ltd., Jiangsu Hengrui Medicine Co., Ltd.
    Inventors: Hejun Lu, Piaoyang Sun, Hongbo Fei, Hongjian Jiang, Haowei Wang, Qing Dong
  • Publication number: 20150225381
    Abstract: New imidazoline derivatives represented by formula (I): preparation methods thereof, pharmaceutical compositions comprising such derivatives, and applications of such derivatives in preparing androgen receptor antagonists and medicaments for treating diseases such as prostate cancer are described.
    Type: Application
    Filed: August 26, 2013
    Publication date: August 13, 2015
    Inventors: Hejun Lu, Piaoyang Sun, Hongbo Fei, Hongjian Jiang, Haowei Wang, Qing Dong
  • Patent number: 8563746
    Abstract: Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: October 22, 2013
    Assignees: Merck Sharp & Dohme Corp, Metabasis Therapeutics, Inc.
    Inventors: Qun Dang, De Michael Chung, Tony S. Gibson, Hongjian Jiang, Daniel K. Cashion, Jianming Bao, Ping Lan, Huagang Lu, Gergely M. Makara, F. Anthony Romero, Iyassu Sebhat, Dariusz Wodka
  • Patent number: 8410284
    Abstract: Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, Metabolic Syndrome, obesity, hypercholesterolemia, and hypertension.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: April 2, 2013
    Assignees: Merck Sharp & Dohme Corp, Metabasis Therapeutics, Inc.
    Inventors: Qun Dang, Tony S. Gibson, Hongjian Jiang, De Michael Chung, Jianming Bao, Jinlong Jiang, Andy Kassick, Ahmet Kekec, Ping Lan, Huagang Lu, Gergely M. Makara, F. Anthony Romero, Iyassu Sebhat, David Wilson, Dariusz Wodka, Brett C. Bookser
  • Patent number: 8394969
    Abstract: Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: March 12, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Brett C. Bookser, Qun Dang, Tony S. Gibson, Hongjian Jiang, De Michael Chung, Jianming Bao, Jinlong Jiang, Andy Kassick, Ahmet Kekec, Ping Lan, Huagang Lu, Gergely M. Makara, F. Anthony Romero, Iyassu Sebhat, David Wilson, Dariusz Wodka