Patents by Inventor HONG-KAI CHEN

HONG-KAI CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-human TIM-3 antibodies and methods of use thereof
    Patent number: 10752688
    Abstract: An anti-human T-cell immunoglobulin domain and mucin domain 3 (TIM-3) antibody, can bind the peptides, comprising the amino-acid sequence RKGDVSL (SEQ ID NO: 9) and/or EKFNLKL (SEQ ID NO: 10) of human TIM-3 protein. The antibody can regulate immune cell activity. The antibody or binding fragment thereof is useful in diagnosis, prognosis, and treatment of cancers that have been reported to express cell-surface TIM-3 such as lung, liver, esophageal cancer and solid tumors.
    Type: Grant
    Filed: December 30, 2017
    Date of Patent: August 25, 2020
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Yu-Chen Yang, Li-Yu Chen, Chia-Hua Li, Pei-Han Tai, Hong-Kai Chen, Ying-Yung Lok, Chih-Yung Hu, Chien-Tsun Kuan, Chung-Hsiun Wu
  • Cloud agent device, cloud storage and file transferring method
    Patent number: 10187469
    Abstract: A cloud agent device including, determines whether the size of the file is less than the size of the remaining capacity of the second cloud storage, validating the verification request information of correctness, sending a affirmative notification to the first cloud storage and transfer the file from the first cloud storage to the second cloud storage when the verification request information is correct. The invention also provides a cloud storage and a file transferring method. The cloud agent device, cloud storage and file transferring method can efficient and accurate transfer of files in a safe condition.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: January 22, 2019
    Assignee: NANNING FUGUI PRECISION INDUSTRIAL CO., LTD.
    Inventors: Hong-Kai Chen, Shih-Pin Chen, Chih-Wei Tung
  • ANTI-HUMAN TIM-3 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20180186881
    Abstract: An anti-human T-cell immunoglobulin domain and mucin domain 3 (TIM-3) antibody, can bind the peptides, comprising the amino-acid sequence RKGDVSL (SEQ ID NO: 9) and/or EKFNLKL (SEQ ID NO: 10) of human TIM-3 protein. The antibody can regulate immune cell activity. The antibody or binding fragment thereof is useful in diagnosis, prognosis, and treatment of cancers that have been reported to express cell-surface TIM-3 such as lung, liver, esophageal cancer and solid tumors.
    Type: Application
    Filed: December 30, 2017
    Publication date: July 5, 2018
    Applicant: Development Center for Biotechnology
    Inventors: Yu-Chen Yang, Li-Yu CHEN, Chia-Hua LI, Pei-Han TAI, Hong-Kai CHEN, Ying-Yung LOK, Chih-Yung HU, Chien-Tsun KUAN, Chung-Hsiun WU
  • CLOUD AGENT DEVICE, CLOUD STORAGE AND FILE TRANSFERRING METHOD
    Publication number: 20160156616
    Abstract: A cloud agent device including, determines whether the size of the file is less than the size of the remaining capacity of the second cloud storage, validating the verification request information of correctness, sending a affirmative notification to the first cloud storage and transfer the file from the first cloud storage to the second cloud storage when the verification request information is correct. The invention also provides a cloud storage and a file transferring method. The cloud agent device, cloud storage and file transferring method can efficient and accurate transfer of files in a safe condition.
    Type: Application
    Filed: December 1, 2015
    Publication date: June 2, 2016
    Inventors: HONG-KAI CHEN, SHIH-PIN CHEN, CHIH-WEI TUNG